| Full name: engulfment and cell motility 3 | Alias Symbol: FLJ13824|CED12|ELMO-3|CED-12 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 79767 | HGNC ID: HGNC:17289 | Ensembl Gene: ENSG00000102890 | OMIM ID: 606422 |
| Drug and gene relationship at DGIdb | |||
ELMO3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05100 | Bacterial invasion of epithelial cells | |
| hsa05131 | Shigellosis |
Expression of ELMO3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELMO3 | 79767 | 219411_at | 0.6677 | 0.1033 | |
| GSE20347 | ELMO3 | 79767 | 219411_at | 0.2050 | 0.2405 | |
| GSE23400 | ELMO3 | 79767 | 219411_at | 0.5304 | 0.0001 | |
| GSE26886 | ELMO3 | 79767 | 219411_at | 0.7200 | 0.0297 | |
| GSE29001 | ELMO3 | 79767 | 219411_at | 0.0360 | 0.9139 | |
| GSE38129 | ELMO3 | 79767 | 219411_at | 0.6855 | 0.0055 | |
| GSE45670 | ELMO3 | 79767 | 219411_at | 0.4556 | 0.0463 | |
| GSE53622 | ELMO3 | 79767 | 39515 | 0.3784 | 0.0655 | |
| GSE53624 | ELMO3 | 79767 | 39515 | 0.3548 | 0.0001 | |
| GSE63941 | ELMO3 | 79767 | 219411_at | 2.5099 | 0.0012 | |
| GSE77861 | ELMO3 | 79767 | 219411_at | 0.5194 | 0.1067 | |
| GSE97050 | ELMO3 | 79767 | A_23_P140830 | 0.3915 | 0.2782 | |
| SRP007169 | ELMO3 | 79767 | RNAseq | -0.6907 | 0.0525 | |
| SRP008496 | ELMO3 | 79767 | RNAseq | -0.6590 | 0.0422 | |
| SRP064894 | ELMO3 | 79767 | RNAseq | 0.5775 | 0.0523 | |
| SRP133303 | ELMO3 | 79767 | RNAseq | 0.1978 | 0.3876 | |
| SRP159526 | ELMO3 | 79767 | RNAseq | 0.2388 | 0.5021 | |
| SRP193095 | ELMO3 | 79767 | RNAseq | 0.0739 | 0.6117 | |
| SRP219564 | ELMO3 | 79767 | RNAseq | 0.4623 | 0.5335 | |
| TCGA | ELMO3 | 79767 | RNAseq | 0.1427 | 0.2828 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ELMO3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELMO3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELMO3 | 79767 | 9 | 2 | 19 | |
| GSE20123 | ELMO3 | 79767 | 9 | 2 | 19 | |
| GSE43470 | ELMO3 | 79767 | 1 | 9 | 33 | |
| GSE46452 | ELMO3 | 79767 | 38 | 1 | 20 | |
| GSE47630 | ELMO3 | 79767 | 10 | 8 | 22 | |
| GSE54993 | ELMO3 | 79767 | 2 | 4 | 64 | |
| GSE54994 | ELMO3 | 79767 | 8 | 10 | 35 | |
| GSE60625 | ELMO3 | 79767 | 4 | 0 | 7 | |
| GSE74703 | ELMO3 | 79767 | 1 | 6 | 29 | |
| GSE74704 | ELMO3 | 79767 | 5 | 1 | 14 | |
| TCGA | ELMO3 | 79767 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of ELMO3:
Generating mutation plots.
Highly correlated genes for ELMO3:
Showing top 20/418 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELMO3 | MEGF10 | 0.74189 | 3 | 0 | 3 |
| ELMO3 | MARVELD2 | 0.708074 | 3 | 0 | 3 |
| ELMO3 | ZNRF2 | 0.706355 | 3 | 0 | 3 |
| ELMO3 | INO80B | 0.70466 | 4 | 0 | 4 |
| ELMO3 | SOX12 | 0.696728 | 3 | 0 | 3 |
| ELMO3 | GPR39 | 0.688878 | 3 | 0 | 3 |
| ELMO3 | DSC2 | 0.679895 | 4 | 0 | 3 |
| ELMO3 | MTFP1 | 0.672668 | 4 | 0 | 3 |
| ELMO3 | TUBA3C | 0.669534 | 3 | 0 | 3 |
| ELMO3 | FBP1 | 0.665036 | 3 | 0 | 3 |
| ELMO3 | F11R | 0.662055 | 8 | 0 | 7 |
| ELMO3 | PDCD11 | 0.661066 | 4 | 0 | 3 |
| ELMO3 | TMEM102 | 0.659529 | 6 | 0 | 6 |
| ELMO3 | KIFC2 | 0.658404 | 3 | 0 | 3 |
| ELMO3 | POM121L12 | 0.658225 | 3 | 0 | 3 |
| ELMO3 | CAPG | 0.655769 | 6 | 0 | 5 |
| ELMO3 | CCDC142 | 0.652778 | 3 | 0 | 3 |
| ELMO3 | BEND3 | 0.6527 | 5 | 0 | 4 |
| ELMO3 | RAPGEF5 | 0.648589 | 4 | 0 | 4 |
| ELMO3 | PRKCD | 0.646797 | 3 | 0 | 3 |
For details and further investigation, click here
