TNRC18

 

Full name: trinucleotide repeat containing 18 Alias Symbol: CAGL79|TNRC18A|KIAA1856
Type: protein-coding gene Cytoband: 7p22.1
Entrez ID: 84629 HGNC ID: HGNC:11962 Ensembl Gene: ENSG00000182095 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TNRC18:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TNRC18 84629 226691_at 0.4164 0.3182
GSE26886 TNRC18 84629 226691_at 0.6425 0.0026
GSE45670 TNRC18 84629 226691_at 0.0210 0.9082
GSE53622 TNRC18 84629 17977 0.3704 0.0000
GSE53624 TNRC18 84629 17977 0.5195 0.0000
GSE63941 TNRC18 84629 226691_at 1.0671 0.0176
GSE77861 TNRC18 84629 226691_at 0.8676 0.0011
GSE97050 TNRC18 84629 A_33_P3321507 0.0927 0.6783
SRP007169 TNRC18 84629 RNAseq 1.6862 0.0000
SRP008496 TNRC18 84629 RNAseq 1.7172 0.0000
SRP064894 TNRC18 84629 RNAseq 0.4463 0.0209
SRP133303 TNRC18 84629 RNAseq 0.3001 0.0416
SRP159526 TNRC18 84629 RNAseq 0.6764 0.0096
SRP193095 TNRC18 84629 RNAseq 0.9777 0.0000
SRP219564 TNRC18 84629 RNAseq 0.1816 0.5535
TCGA TNRC18 84629 RNAseq 0.0274 0.4930

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by TNRC18 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TNRC18:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TNRC18 84629 14 1 15
GSE20123 TNRC18 84629 14 1 15
GSE43470 TNRC18 84629 6 1 36
GSE46452 TNRC18 84629 13 1 45
GSE47630 TNRC18 84629 9 1 30
GSE54993 TNRC18 84629 0 6 64
GSE54994 TNRC18 84629 22 1 30
GSE60625 TNRC18 84629 0 0 11
GSE74703 TNRC18 84629 6 0 30
GSE74704 TNRC18 84629 9 0 11
TCGA TNRC18 84629 56 5 35

Total number of gains: 149; Total number of losses: 17; Total Number of normals: 322.  


 

Somatic mutations of TNRC18:

 

Generating mutation plots.

 

Highly correlated genes for TNRC18:

 

Showing top 20/902 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TNRC18CCDC930.806349303
TNRC18WDR810.797055303
TNRC18KIF16B0.792706303
TNRC18CDKN1C0.786458303
TNRC18RAD23A0.769915505
TNRC18SLC39A30.763765303
TNRC18PIK3R30.76132303
TNRC18ZNF7030.760563303
TNRC18RILPL10.760242505
TNRC18ALKBH60.756257404
TNRC18TIPRL0.754717303
TNRC18ZDHHC90.753661303
TNRC18RNMT0.74918303
TNRC18LTBR0.748103303
TNRC18TMEM2300.74476303
TNRC18UBB0.743181303
TNRC18TMEM63B0.737975303
TNRC18SLC39A10.736498403
TNRC18PPP1R100.73233303
TNRC18ABL10.726531403

For details and further investigation, click here