| Full name: agrin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 375790 | HGNC ID: HGNC:329 | Ensembl Gene: ENSG00000188157 | OMIM ID: 103320 |
| Drug and gene relationship at DGIdb | |||
Expression of AGRN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGRN | 375790 | 212285_s_at | 1.5269 | 0.0130 | |
| GSE20347 | AGRN | 375790 | 212285_s_at | 1.3053 | 0.0000 | |
| GSE23400 | AGRN | 375790 | 217419_x_at | 1.0983 | 0.0000 | |
| GSE26886 | AGRN | 375790 | 212285_s_at | 1.0995 | 0.0000 | |
| GSE29001 | AGRN | 375790 | 212285_s_at | 0.7392 | 0.0126 | |
| GSE38129 | AGRN | 375790 | 212285_s_at | 1.3084 | 0.0000 | |
| GSE45670 | AGRN | 375790 | 212285_s_at | 1.0221 | 0.0000 | |
| GSE53622 | AGRN | 375790 | 174386 | 1.4163 | 0.0000 | |
| GSE53624 | AGRN | 375790 | 174386 | 1.6230 | 0.0000 | |
| GSE63941 | AGRN | 375790 | 212285_s_at | 1.2306 | 0.0129 | |
| GSE77861 | AGRN | 375790 | 212285_s_at | 0.7594 | 0.0081 | |
| GSE97050 | AGRN | 375790 | A_23_P343411 | 1.0371 | 0.0737 | |
| SRP007169 | AGRN | 375790 | RNAseq | 1.9541 | 0.0017 | |
| SRP008496 | AGRN | 375790 | RNAseq | 1.7736 | 0.0000 | |
| SRP064894 | AGRN | 375790 | RNAseq | 1.8864 | 0.0000 | |
| SRP133303 | AGRN | 375790 | RNAseq | 1.6787 | 0.0000 | |
| SRP159526 | AGRN | 375790 | RNAseq | 1.4534 | 0.0012 | |
| SRP193095 | AGRN | 375790 | RNAseq | 1.5341 | 0.0000 | |
| SRP219564 | AGRN | 375790 | RNAseq | 1.2221 | 0.0034 | |
| TCGA | AGRN | 375790 | RNAseq | 0.3225 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by AGRN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGRN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGRN | 375790 | 3 | 7 | 20 | |
| GSE20123 | AGRN | 375790 | 3 | 6 | 21 | |
| GSE43470 | AGRN | 375790 | 1 | 5 | 37 | |
| GSE46452 | AGRN | 375790 | 7 | 1 | 51 | |
| GSE47630 | AGRN | 375790 | 8 | 4 | 28 | |
| GSE54993 | AGRN | 375790 | 2 | 2 | 66 | |
| GSE54994 | AGRN | 375790 | 15 | 2 | 36 | |
| GSE60625 | AGRN | 375790 | 0 | 0 | 11 | |
| GSE74703 | AGRN | 375790 | 1 | 3 | 32 | |
| GSE74704 | AGRN | 375790 | 3 | 0 | 17 | |
| TCGA | AGRN | 375790 | 14 | 20 | 62 |
Total number of gains: 57; Total number of losses: 50; Total Number of normals: 381.
Somatic mutations of AGRN:
Generating mutation plots.
Highly correlated genes for AGRN:
Showing top 20/2182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGRN | RTKN | 0.805095 | 7 | 0 | 7 |
| AGRN | PLAU | 0.787923 | 11 | 0 | 11 |
| AGRN | B3GALT6 | 0.784365 | 6 | 0 | 6 |
| AGRN | SPON2 | 0.781534 | 3 | 0 | 3 |
| AGRN | ITGB4 | 0.781391 | 13 | 0 | 13 |
| AGRN | SLC39A3 | 0.78089 | 4 | 0 | 4 |
| AGRN | PTK7 | 0.780543 | 11 | 0 | 11 |
| AGRN | UBB | 0.776815 | 3 | 0 | 3 |
| AGRN | KRTCAP2 | 0.77532 | 5 | 0 | 5 |
| AGRN | TP53I13 | 0.774508 | 6 | 0 | 6 |
| AGRN | FBLIM1 | 0.773791 | 7 | 0 | 7 |
| AGRN | CCM2 | 0.770067 | 8 | 0 | 7 |
| AGRN | BRAT1 | 0.768679 | 7 | 0 | 7 |
| AGRN | FAM126A | 0.765863 | 3 | 0 | 3 |
| AGRN | COLGALT1 | 0.763845 | 10 | 0 | 10 |
| AGRN | RILPL2 | 0.763351 | 3 | 0 | 3 |
| AGRN | CNTROB | 0.761059 | 6 | 0 | 6 |
| AGRN | LPCAT1 | 0.757325 | 11 | 0 | 11 |
| AGRN | DTX3L | 0.75094 | 6 | 0 | 6 |
| AGRN | COL7A1 | 0.750851 | 11 | 0 | 11 |
For details and further investigation, click here
