| Full name: PTTG1 interacting protein | Alias Symbol: PBF | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 754 | HGNC ID: HGNC:13524 | Ensembl Gene: ENSG00000183255 | OMIM ID: 603784 |
| Drug and gene relationship at DGIdb | |||
Expression of PTTG1IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTTG1IP | 754 | 200677_at | -0.0193 | 0.9789 | |
| GSE20347 | PTTG1IP | 754 | 200677_at | 0.1119 | 0.3627 | |
| GSE23400 | PTTG1IP | 754 | 200677_at | 0.1712 | 0.0249 | |
| GSE26886 | PTTG1IP | 754 | 200677_at | -0.0874 | 0.7188 | |
| GSE29001 | PTTG1IP | 754 | 200677_at | 0.2425 | 0.3802 | |
| GSE38129 | PTTG1IP | 754 | 200677_at | 0.0366 | 0.7794 | |
| GSE45670 | PTTG1IP | 754 | 200677_at | -0.1606 | 0.3773 | |
| GSE53622 | PTTG1IP | 754 | 94788 | -0.1604 | 0.0240 | |
| GSE53624 | PTTG1IP | 754 | 52589 | 0.1352 | 0.0355 | |
| GSE63941 | PTTG1IP | 754 | 200677_at | -1.5779 | 0.0067 | |
| GSE77861 | PTTG1IP | 754 | 200677_at | -0.2054 | 0.3350 | |
| GSE97050 | PTTG1IP | 754 | A_24_P391260 | 0.2160 | 0.2942 | |
| SRP007169 | PTTG1IP | 754 | RNAseq | -0.3395 | 0.4240 | |
| SRP008496 | PTTG1IP | 754 | RNAseq | -0.0113 | 0.9630 | |
| SRP064894 | PTTG1IP | 754 | RNAseq | 0.3795 | 0.0418 | |
| SRP133303 | PTTG1IP | 754 | RNAseq | 0.2212 | 0.1897 | |
| SRP159526 | PTTG1IP | 754 | RNAseq | 0.1339 | 0.4593 | |
| SRP193095 | PTTG1IP | 754 | RNAseq | -0.3933 | 0.0333 | |
| SRP219564 | PTTG1IP | 754 | RNAseq | -0.1379 | 0.6920 | |
| TCGA | PTTG1IP | 754 | RNAseq | -0.2375 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PTTG1IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTTG1IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTTG1IP | 754 | 2 | 9 | 19 | |
| GSE20123 | PTTG1IP | 754 | 2 | 9 | 19 | |
| GSE43470 | PTTG1IP | 754 | 0 | 13 | 30 | |
| GSE46452 | PTTG1IP | 754 | 1 | 21 | 37 | |
| GSE47630 | PTTG1IP | 754 | 6 | 17 | 17 | |
| GSE54993 | PTTG1IP | 754 | 8 | 1 | 61 | |
| GSE54994 | PTTG1IP | 754 | 4 | 8 | 41 | |
| GSE60625 | PTTG1IP | 754 | 0 | 0 | 11 | |
| GSE74703 | PTTG1IP | 754 | 0 | 10 | 26 | |
| GSE74704 | PTTG1IP | 754 | 1 | 5 | 14 | |
| TCGA | PTTG1IP | 754 | 9 | 38 | 49 |
Total number of gains: 33; Total number of losses: 131; Total Number of normals: 324.
Somatic mutations of PTTG1IP:
Generating mutation plots.
Highly correlated genes for PTTG1IP:
Showing top 20/532 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTTG1IP | KIAA2013 | 0.756402 | 3 | 0 | 3 |
| PTTG1IP | ZNF578 | 0.747922 | 3 | 0 | 3 |
| PTTG1IP | UBB | 0.74764 | 3 | 0 | 3 |
| PTTG1IP | HERC4 | 0.746553 | 3 | 0 | 3 |
| PTTG1IP | VPS18 | 0.740884 | 3 | 0 | 3 |
| PTTG1IP | PMPCB | 0.739772 | 3 | 0 | 3 |
| PTTG1IP | STAM | 0.716786 | 3 | 0 | 3 |
| PTTG1IP | ANKS3 | 0.71595 | 3 | 0 | 3 |
| PTTG1IP | PDE8A | 0.715808 | 3 | 0 | 3 |
| PTTG1IP | STOML1 | 0.715349 | 3 | 0 | 3 |
| PTTG1IP | SPATA9 | 0.707659 | 3 | 0 | 3 |
| PTTG1IP | ACSS3 | 0.693932 | 5 | 0 | 4 |
| PTTG1IP | NUB1 | 0.69174 | 4 | 0 | 4 |
| PTTG1IP | NAIF1 | 0.688097 | 3 | 0 | 3 |
| PTTG1IP | C12orf4 | 0.684256 | 3 | 0 | 3 |
| PTTG1IP | RUNDC1 | 0.683889 | 3 | 0 | 3 |
| PTTG1IP | GALM | 0.681086 | 3 | 0 | 3 |
| PTTG1IP | SCAI | 0.679186 | 3 | 0 | 3 |
| PTTG1IP | ZNF10 | 0.67141 | 4 | 0 | 4 |
| PTTG1IP | TEX264 | 0.670964 | 3 | 0 | 3 |
For details and further investigation, click here
