| Full name: vestigial like family member 3 | Alias Symbol: VGL-3 | ||
| Type: protein-coding gene | Cytoband: 3p12.1 | ||
| Entrez ID: 389136 | HGNC ID: HGNC:24327 | Ensembl Gene: ENSG00000206538 | OMIM ID: 609980 |
| Drug and gene relationship at DGIdb | |||
Expression of VGLL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VGLL3 | 389136 | 227399_at | -0.5085 | 0.5301 | |
| GSE20347 | VGLL3 | 389136 | 220327_at | -0.0237 | 0.8213 | |
| GSE23400 | VGLL3 | 389136 | 220327_at | -0.0431 | 0.1635 | |
| GSE26886 | VGLL3 | 389136 | 227399_at | 1.3834 | 0.0032 | |
| GSE29001 | VGLL3 | 389136 | 220327_at | -0.1872 | 0.0939 | |
| GSE38129 | VGLL3 | 389136 | 220327_at | -0.4258 | 0.0480 | |
| GSE45670 | VGLL3 | 389136 | 227399_at | -1.2064 | 0.0069 | |
| GSE53622 | VGLL3 | 389136 | 51592 | 0.4237 | 0.0077 | |
| GSE53624 | VGLL3 | 389136 | 51592 | 0.5072 | 0.0000 | |
| GSE63941 | VGLL3 | 389136 | 227399_at | -6.0636 | 0.0010 | |
| GSE77861 | VGLL3 | 389136 | 227399_at | 0.1639 | 0.4381 | |
| GSE97050 | VGLL3 | 389136 | A_24_P67585 | 0.1796 | 0.5508 | |
| SRP007169 | VGLL3 | 389136 | RNAseq | 3.4791 | 0.0000 | |
| SRP008496 | VGLL3 | 389136 | RNAseq | 4.1101 | 0.0000 | |
| SRP064894 | VGLL3 | 389136 | RNAseq | 0.9619 | 0.0436 | |
| SRP133303 | VGLL3 | 389136 | RNAseq | 1.9943 | 0.0005 | |
| SRP159526 | VGLL3 | 389136 | RNAseq | -0.0209 | 0.9500 | |
| SRP193095 | VGLL3 | 389136 | RNAseq | 1.3566 | 0.0000 | |
| SRP219564 | VGLL3 | 389136 | RNAseq | 0.5377 | 0.1551 | |
| TCGA | VGLL3 | 389136 | RNAseq | -0.2394 | 0.1455 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by VGLL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VGLL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VGLL3 | 389136 | 3 | 16 | 11 | |
| GSE20123 | VGLL3 | 389136 | 3 | 16 | 11 | |
| GSE43470 | VGLL3 | 389136 | 3 | 19 | 21 | |
| GSE46452 | VGLL3 | 389136 | 2 | 17 | 40 | |
| GSE47630 | VGLL3 | 389136 | 4 | 18 | 18 | |
| GSE54993 | VGLL3 | 389136 | 4 | 3 | 63 | |
| GSE54994 | VGLL3 | 389136 | 3 | 27 | 23 | |
| GSE60625 | VGLL3 | 389136 | 0 | 6 | 5 | |
| GSE74703 | VGLL3 | 389136 | 3 | 17 | 16 | |
| GSE74704 | VGLL3 | 389136 | 2 | 11 | 7 | |
| TCGA | VGLL3 | 389136 | 4 | 72 | 20 |
Total number of gains: 31; Total number of losses: 222; Total Number of normals: 235.
Somatic mutations of VGLL3:
Generating mutation plots.
Highly correlated genes for VGLL3:
Showing top 20/867 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VGLL3 | C11orf96 | 0.745209 | 5 | 0 | 5 |
| VGLL3 | ZNF583 | 0.740456 | 3 | 0 | 3 |
| VGLL3 | COLEC12 | 0.739041 | 11 | 0 | 11 |
| VGLL3 | JMY | 0.73841 | 3 | 0 | 3 |
| VGLL3 | DLC1 | 0.733652 | 9 | 0 | 8 |
| VGLL3 | C16orf86 | 0.733291 | 3 | 0 | 3 |
| VGLL3 | LAMA4 | 0.728507 | 11 | 0 | 11 |
| VGLL3 | DNM3OS | 0.727618 | 3 | 0 | 3 |
| VGLL3 | OLFML1 | 0.724014 | 11 | 0 | 11 |
| VGLL3 | ZEB2 | 0.721995 | 8 | 0 | 8 |
| VGLL3 | FIBIN | 0.721772 | 5 | 0 | 5 |
| VGLL3 | CLMP | 0.719832 | 7 | 0 | 7 |
| VGLL3 | S1PR1 | 0.71944 | 6 | 0 | 6 |
| VGLL3 | STARD13 | 0.71373 | 10 | 0 | 10 |
| VGLL3 | KCNK2 | 0.713543 | 3 | 0 | 3 |
| VGLL3 | FBN1 | 0.713485 | 10 | 0 | 8 |
| VGLL3 | COL6A1 | 0.711239 | 12 | 0 | 12 |
| VGLL3 | PMP22 | 0.703987 | 11 | 0 | 10 |
| VGLL3 | NKAPL | 0.703914 | 3 | 0 | 3 |
| VGLL3 | EBF1 | 0.703535 | 5 | 0 | 5 |
For details and further investigation, click here
