| Full name: EBF transcription factor 1 | Alias Symbol: OLF1|COE1 | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 1879 | HGNC ID: HGNC:3126 | Ensembl Gene: ENSG00000164330 | OMIM ID: 164343 |
| Drug and gene relationship at DGIdb | |||
Expression of EBF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EBF1 | 1879 | 227646_at | -0.9854 | 0.1762 | |
| GSE26886 | EBF1 | 1879 | 227646_at | 0.9486 | 0.0337 | |
| GSE45670 | EBF1 | 1879 | 227646_at | -2.3477 | 0.0000 | |
| GSE53622 | EBF1 | 1879 | 144218 | -1.3362 | 0.0000 | |
| GSE53624 | EBF1 | 1879 | 144218 | -1.0669 | 0.0000 | |
| GSE63941 | EBF1 | 1879 | 227646_at | -3.3897 | 0.0002 | |
| GSE77861 | EBF1 | 1879 | 229487_at | 0.0768 | 0.4562 | |
| GSE97050 | EBF1 | 1879 | A_33_P3241521 | -0.2566 | 0.4039 | |
| SRP007169 | EBF1 | 1879 | RNAseq | 1.3478 | 0.1225 | |
| SRP064894 | EBF1 | 1879 | RNAseq | -0.0875 | 0.8168 | |
| SRP133303 | EBF1 | 1879 | RNAseq | -1.0485 | 0.0000 | |
| SRP159526 | EBF1 | 1879 | RNAseq | -1.2807 | 0.0002 | |
| SRP193095 | EBF1 | 1879 | RNAseq | 0.7850 | 0.0003 | |
| SRP219564 | EBF1 | 1879 | RNAseq | 0.1933 | 0.7681 | |
| TCGA | EBF1 | 1879 | RNAseq | -0.4248 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by EBF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EBF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EBF1 | 1879 | 0 | 11 | 19 | |
| GSE20123 | EBF1 | 1879 | 0 | 11 | 19 | |
| GSE43470 | EBF1 | 1879 | 2 | 10 | 31 | |
| GSE46452 | EBF1 | 1879 | 0 | 27 | 32 | |
| GSE47630 | EBF1 | 1879 | 0 | 20 | 20 | |
| GSE54993 | EBF1 | 1879 | 9 | 1 | 60 | |
| GSE54994 | EBF1 | 1879 | 1 | 16 | 36 | |
| GSE60625 | EBF1 | 1879 | 0 | 0 | 11 | |
| GSE74703 | EBF1 | 1879 | 2 | 8 | 26 | |
| GSE74704 | EBF1 | 1879 | 0 | 6 | 14 | |
| TCGA | EBF1 | 1879 | 5 | 36 | 55 |
Total number of gains: 19; Total number of losses: 146; Total Number of normals: 323.
Somatic mutations of EBF1:
Generating mutation plots.
Highly correlated genes for EBF1:
Showing top 20/1145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EBF1 | PREX2 | 0.852257 | 4 | 0 | 4 |
| EBF1 | COL14A1 | 0.847081 | 6 | 0 | 6 |
| EBF1 | FHL5 | 0.843318 | 5 | 0 | 5 |
| EBF1 | DIXDC1 | 0.83023 | 6 | 0 | 6 |
| EBF1 | MYCT1 | 0.828862 | 6 | 0 | 6 |
| EBF1 | CLEC3B | 0.823682 | 3 | 0 | 3 |
| EBF1 | TEK | 0.811463 | 5 | 0 | 5 |
| EBF1 | BHLHE22 | 0.810124 | 5 | 0 | 5 |
| EBF1 | SYNE1 | 0.809832 | 7 | 0 | 7 |
| EBF1 | MEOX2 | 0.808091 | 5 | 0 | 5 |
| EBF1 | SMPD1 | 0.805709 | 3 | 0 | 3 |
| EBF1 | JAM2 | 0.799631 | 7 | 0 | 7 |
| EBF1 | GIMAP5 | 0.798514 | 3 | 0 | 3 |
| EBF1 | C11orf96 | 0.788326 | 5 | 0 | 5 |
| EBF1 | ABCA8 | 0.787798 | 6 | 0 | 6 |
| EBF1 | IL3RA | 0.784435 | 3 | 0 | 3 |
| EBF1 | NPY1R | 0.781364 | 3 | 0 | 3 |
| EBF1 | SEMA3G | 0.78022 | 4 | 0 | 4 |
| EBF1 | ADH1B | 0.780218 | 6 | 0 | 6 |
| EBF1 | SLC16A4 | 0.776799 | 7 | 0 | 7 |
For details and further investigation, click here
