| Full name: V-set pre-B cell surrogate light chain 1 | Alias Symbol: VpreB|CD179A | ||
| Type: protein-coding gene | Cytoband: 22q11.22 | ||
| Entrez ID: 7441 | HGNC ID: HGNC:12709 | Ensembl Gene: ENSG00000169575 | OMIM ID: 605141 |
| Drug and gene relationship at DGIdb | |||
Expression of VPREB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPREB1 | 7441 | 221349_at | -0.0159 | 0.9510 | |
| GSE20347 | VPREB1 | 7441 | 221349_at | 0.0027 | 0.9696 | |
| GSE23400 | VPREB1 | 7441 | 221349_at | -0.0081 | 0.6226 | |
| GSE26886 | VPREB1 | 7441 | 221349_at | 0.2694 | 0.0035 | |
| GSE29001 | VPREB1 | 7441 | 221349_at | 0.0823 | 0.3376 | |
| GSE38129 | VPREB1 | 7441 | 221349_at | 0.0094 | 0.8768 | |
| GSE45670 | VPREB1 | 7441 | 221349_at | 0.0942 | 0.2491 | |
| GSE53622 | VPREB1 | 7441 | 155623 | -0.0279 | 0.8380 | |
| GSE53624 | VPREB1 | 7441 | 40209 | -0.4968 | 0.0000 | |
| GSE63941 | VPREB1 | 7441 | 221349_at | -0.0952 | 0.5429 | |
| GSE77861 | VPREB1 | 7441 | 221349_at | 0.0136 | 0.8985 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPREB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPREB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPREB1 | 7441 | 5 | 7 | 18 | |
| GSE20123 | VPREB1 | 7441 | 5 | 6 | 19 | |
| GSE43470 | VPREB1 | 7441 | 3 | 7 | 33 | |
| GSE46452 | VPREB1 | 7441 | 33 | 1 | 25 | |
| GSE47630 | VPREB1 | 7441 | 8 | 5 | 27 | |
| GSE54993 | VPREB1 | 7441 | 3 | 6 | 61 | |
| GSE54994 | VPREB1 | 7441 | 11 | 7 | 35 | |
| GSE60625 | VPREB1 | 7441 | 5 | 0 | 6 | |
| GSE74703 | VPREB1 | 7441 | 3 | 6 | 27 | |
| GSE74704 | VPREB1 | 7441 | 2 | 3 | 15 | |
| TCGA | VPREB1 | 7441 | 27 | 16 | 53 |
Total number of gains: 105; Total number of losses: 64; Total Number of normals: 319.
Somatic mutations of VPREB1:
Generating mutation plots.
Highly correlated genes for VPREB1:
Showing all 19 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPREB1 | PNMA2 | 0.637906 | 3 | 0 | 3 |
| VPREB1 | DPPA4 | 0.622209 | 3 | 0 | 3 |
| VPREB1 | TPO | 0.621033 | 3 | 0 | 3 |
| VPREB1 | PICK1 | 0.61531 | 3 | 0 | 3 |
| VPREB1 | PATE1 | 0.59423 | 3 | 0 | 3 |
| VPREB1 | JSRP1 | 0.585808 | 3 | 0 | 3 |
| VPREB1 | HCN2 | 0.571419 | 3 | 0 | 3 |
| VPREB1 | C19orf81 | 0.570004 | 4 | 0 | 3 |
| VPREB1 | LINC01364 | 0.568423 | 4 | 0 | 3 |
| VPREB1 | GLTPD2 | 0.567996 | 3 | 0 | 3 |
| VPREB1 | ADRA2C | 0.562507 | 3 | 0 | 3 |
| VPREB1 | MAST2 | 0.552495 | 4 | 0 | 3 |
| VPREB1 | ZNF839 | 0.546979 | 3 | 0 | 3 |
| VPREB1 | SUN3 | 0.537837 | 3 | 0 | 3 |
| VPREB1 | DDX24 | 0.526712 | 4 | 0 | 3 |
| VPREB1 | ADCY8 | 0.523841 | 5 | 0 | 3 |
| VPREB1 | BANP | 0.514876 | 4 | 0 | 3 |
| VPREB1 | TUT1 | 0.508395 | 5 | 0 | 3 |
| VPREB1 | COL20A1 | 0.507984 | 4 | 0 | 3 |
For details and further investigation, click here
