| Full name: DEAD-box helicase 24 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 57062 | HGNC ID: HGNC:13266 | Ensembl Gene: ENSG00000089737 | OMIM ID: 606181 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDX24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX24 | 57062 | 200694_s_at | 0.0976 | 0.8114 | |
| GSE20347 | DDX24 | 57062 | 200694_s_at | 0.4503 | 0.0001 | |
| GSE23400 | DDX24 | 57062 | 200694_s_at | 0.3695 | 0.0000 | |
| GSE26886 | DDX24 | 57062 | 200694_s_at | 0.9682 | 0.0000 | |
| GSE29001 | DDX24 | 57062 | 200694_s_at | 0.4954 | 0.0015 | |
| GSE38129 | DDX24 | 57062 | 200694_s_at | 0.2225 | 0.0912 | |
| GSE45670 | DDX24 | 57062 | 200694_s_at | 0.1113 | 0.5316 | |
| GSE53622 | DDX24 | 57062 | 99546 | 0.3037 | 0.0000 | |
| GSE53624 | DDX24 | 57062 | 99546 | 0.4209 | 0.0000 | |
| GSE63941 | DDX24 | 57062 | 200694_s_at | -0.0999 | 0.8158 | |
| GSE77861 | DDX24 | 57062 | 200694_s_at | 0.3893 | 0.2272 | |
| GSE97050 | DDX24 | 57062 | A_23_P151544 | 0.0245 | 0.9318 | |
| SRP007169 | DDX24 | 57062 | RNAseq | 0.8528 | 0.0218 | |
| SRP008496 | DDX24 | 57062 | RNAseq | 0.9103 | 0.0000 | |
| SRP064894 | DDX24 | 57062 | RNAseq | 0.3019 | 0.0120 | |
| SRP133303 | DDX24 | 57062 | RNAseq | 0.2827 | 0.0586 | |
| SRP159526 | DDX24 | 57062 | RNAseq | 0.1400 | 0.6330 | |
| SRP193095 | DDX24 | 57062 | RNAseq | 0.4415 | 0.0000 | |
| SRP219564 | DDX24 | 57062 | RNAseq | 0.3230 | 0.4286 | |
| TCGA | DDX24 | 57062 | RNAseq | -0.0273 | 0.5157 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX24 | 57062 | 9 | 4 | 17 | |
| GSE20123 | DDX24 | 57062 | 9 | 3 | 18 | |
| GSE43470 | DDX24 | 57062 | 7 | 3 | 33 | |
| GSE46452 | DDX24 | 57062 | 16 | 3 | 40 | |
| GSE47630 | DDX24 | 57062 | 11 | 8 | 21 | |
| GSE54993 | DDX24 | 57062 | 3 | 8 | 59 | |
| GSE54994 | DDX24 | 57062 | 20 | 4 | 29 | |
| GSE60625 | DDX24 | 57062 | 0 | 2 | 9 | |
| GSE74703 | DDX24 | 57062 | 6 | 3 | 27 | |
| GSE74704 | DDX24 | 57062 | 5 | 3 | 12 | |
| TCGA | DDX24 | 57062 | 30 | 20 | 46 |
Total number of gains: 116; Total number of losses: 61; Total Number of normals: 311.
Somatic mutations of DDX24:
Generating mutation plots.
Highly correlated genes for DDX24:
Showing top 20/1162 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX24 | PMP22 | 0.760141 | 3 | 0 | 3 |
| DDX24 | B3GALT6 | 0.751689 | 3 | 0 | 3 |
| DDX24 | IRF2BP2 | 0.734633 | 3 | 0 | 3 |
| DDX24 | TTC7B | 0.734298 | 6 | 0 | 6 |
| DDX24 | ZNF114 | 0.720456 | 3 | 0 | 3 |
| DDX24 | CHIC1 | 0.711738 | 3 | 0 | 3 |
| DDX24 | ZNF23 | 0.701986 | 3 | 0 | 3 |
| DDX24 | FPGS | 0.70157 | 3 | 0 | 3 |
| DDX24 | KANK4 | 0.696628 | 3 | 0 | 3 |
| DDX24 | SP100 | 0.69607 | 6 | 0 | 5 |
| DDX24 | ASB2 | 0.693676 | 5 | 0 | 4 |
| DDX24 | CLASP1 | 0.690047 | 3 | 0 | 3 |
| DDX24 | ZNF787 | 0.688811 | 3 | 0 | 3 |
| DDX24 | KDM6B | 0.681938 | 3 | 0 | 3 |
| DDX24 | MMP15 | 0.680674 | 6 | 0 | 5 |
| DDX24 | LNP1 | 0.679559 | 4 | 0 | 4 |
| DDX24 | SGCE | 0.679445 | 3 | 0 | 3 |
| DDX24 | DYNC1H1 | 0.678388 | 10 | 0 | 9 |
| DDX24 | LSM10 | 0.672525 | 4 | 0 | 3 |
| DDX24 | HABP4 | 0.67085 | 5 | 0 | 4 |
For details and further investigation, click here
