| Full name: protein interacting with PRKCA 1 | Alias Symbol: dJ1039K5|MGC15204 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 9463 | HGNC ID: HGNC:9394 | Ensembl Gene: ENSG00000100151 | OMIM ID: 605926 |
| Drug and gene relationship at DGIdb | |||
Expression of PICK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PICK1 | 9463 | 204746_s_at | -0.0475 | 0.8842 | |
| GSE20347 | PICK1 | 9463 | 204746_s_at | 0.0280 | 0.7206 | |
| GSE23400 | PICK1 | 9463 | 204746_s_at | -0.1399 | 0.0004 | |
| GSE26886 | PICK1 | 9463 | 204746_s_at | 0.3760 | 0.0035 | |
| GSE29001 | PICK1 | 9463 | 204746_s_at | -0.0832 | 0.6616 | |
| GSE38129 | PICK1 | 9463 | 204746_s_at | -0.0326 | 0.6646 | |
| GSE45670 | PICK1 | 9463 | 204746_s_at | 0.0772 | 0.2201 | |
| GSE53622 | PICK1 | 9463 | 26805 | -0.0448 | 0.2287 | |
| GSE53624 | PICK1 | 9463 | 26805 | 0.0268 | 0.6415 | |
| GSE63941 | PICK1 | 9463 | 204746_s_at | 0.1926 | 0.3539 | |
| GSE77861 | PICK1 | 9463 | 204746_s_at | -0.0021 | 0.9914 | |
| GSE97050 | PICK1 | 9463 | A_33_P3398697 | -0.0546 | 0.7810 | |
| SRP007169 | PICK1 | 9463 | RNAseq | -0.2064 | 0.5610 | |
| SRP008496 | PICK1 | 9463 | RNAseq | -0.5794 | 0.0247 | |
| SRP064894 | PICK1 | 9463 | RNAseq | 0.3351 | 0.1055 | |
| SRP133303 | PICK1 | 9463 | RNAseq | -0.2758 | 0.0476 | |
| SRP159526 | PICK1 | 9463 | RNAseq | 0.2203 | 0.4535 | |
| SRP193095 | PICK1 | 9463 | RNAseq | 0.1073 | 0.4225 | |
| SRP219564 | PICK1 | 9463 | RNAseq | 0.2488 | 0.4701 | |
| TCGA | PICK1 | 9463 | RNAseq | -0.1328 | 0.0165 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PICK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PICK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PICK1 | 9463 | 6 | 5 | 19 | |
| GSE20123 | PICK1 | 9463 | 6 | 4 | 20 | |
| GSE43470 | PICK1 | 9463 | 6 | 6 | 31 | |
| GSE46452 | PICK1 | 9463 | 32 | 2 | 25 | |
| GSE47630 | PICK1 | 9463 | 9 | 4 | 27 | |
| GSE54993 | PICK1 | 9463 | 3 | 6 | 61 | |
| GSE54994 | PICK1 | 9463 | 9 | 7 | 37 | |
| GSE60625 | PICK1 | 9463 | 5 | 0 | 6 | |
| GSE74703 | PICK1 | 9463 | 5 | 4 | 27 | |
| GSE74704 | PICK1 | 9463 | 3 | 2 | 15 | |
| TCGA | PICK1 | 9463 | 27 | 15 | 54 |
Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.
Somatic mutations of PICK1:
Generating mutation plots.
Highly correlated genes for PICK1:
Showing top 20/424 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PICK1 | CPAMD8 | 0.788531 | 3 | 0 | 3 |
| PICK1 | LINC00598 | 0.770982 | 3 | 0 | 3 |
| PICK1 | LY6H | 0.770641 | 3 | 0 | 3 |
| PICK1 | TTLL9 | 0.760498 | 3 | 0 | 3 |
| PICK1 | TNNC2 | 0.753399 | 4 | 0 | 4 |
| PICK1 | MGAT5B | 0.750183 | 4 | 0 | 4 |
| PICK1 | OLIG3 | 0.748515 | 3 | 0 | 3 |
| PICK1 | RASL10B | 0.74498 | 5 | 0 | 4 |
| PICK1 | GPC2 | 0.744114 | 3 | 0 | 3 |
| PICK1 | DNAJB8 | 0.742392 | 3 | 0 | 3 |
| PICK1 | CDC42EP2 | 0.725689 | 3 | 0 | 3 |
| PICK1 | ZNF182 | 0.721969 | 4 | 0 | 3 |
| PICK1 | C19orf44 | 0.718844 | 4 | 0 | 3 |
| PICK1 | ARID3A | 0.714421 | 3 | 0 | 3 |
| PICK1 | ARHGAP30 | 0.703761 | 4 | 0 | 3 |
| PICK1 | PNMA6A | 0.702293 | 3 | 0 | 3 |
| PICK1 | RPP25 | 0.696307 | 4 | 0 | 3 |
| PICK1 | SP6 | 0.693721 | 3 | 0 | 3 |
| PICK1 | LTB4R | 0.69298 | 3 | 0 | 3 |
| PICK1 | LIF | 0.689453 | 3 | 0 | 3 |
For details and further investigation, click here
