| Full name: microtubule associated serine/threonine kinase 2 | Alias Symbol: MAST205|KIAA0807 | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 23139 | HGNC ID: HGNC:19035 | Ensembl Gene: ENSG00000086015 | OMIM ID: 612257 |
| Drug and gene relationship at DGIdb | |||
Expression of MAST2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAST2 | 23139 | 211593_s_at | 0.1828 | 0.7035 | |
| GSE20347 | MAST2 | 23139 | 215903_s_at | 0.6226 | 0.0003 | |
| GSE23400 | MAST2 | 23139 | 211593_s_at | 0.2222 | 0.0000 | |
| GSE26886 | MAST2 | 23139 | 215903_s_at | 1.4062 | 0.0000 | |
| GSE29001 | MAST2 | 23139 | 215903_s_at | 0.3848 | 0.2212 | |
| GSE38129 | MAST2 | 23139 | 211593_s_at | 0.2080 | 0.1164 | |
| GSE45670 | MAST2 | 23139 | 215903_s_at | 0.0998 | 0.4634 | |
| GSE53622 | MAST2 | 23139 | 47542 | 0.3194 | 0.0002 | |
| GSE53624 | MAST2 | 23139 | 47542 | 0.6701 | 0.0000 | |
| GSE63941 | MAST2 | 23139 | 211593_s_at | 0.1166 | 0.7140 | |
| GSE77861 | MAST2 | 23139 | 215661_at | -0.0847 | 0.6370 | |
| GSE97050 | MAST2 | 23139 | A_23_P126008 | -0.0032 | 0.9925 | |
| SRP007169 | MAST2 | 23139 | RNAseq | 1.7616 | 0.0000 | |
| SRP008496 | MAST2 | 23139 | RNAseq | 1.7725 | 0.0000 | |
| SRP064894 | MAST2 | 23139 | RNAseq | 1.3298 | 0.0000 | |
| SRP133303 | MAST2 | 23139 | RNAseq | 0.6884 | 0.0000 | |
| SRP159526 | MAST2 | 23139 | RNAseq | 0.5343 | 0.1646 | |
| SRP193095 | MAST2 | 23139 | RNAseq | 0.7409 | 0.0000 | |
| SRP219564 | MAST2 | 23139 | RNAseq | 0.4654 | 0.2438 | |
| TCGA | MAST2 | 23139 | RNAseq | 0.0165 | 0.7407 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by MAST2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAST2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAST2 | 23139 | 4 | 3 | 23 | |
| GSE20123 | MAST2 | 23139 | 4 | 2 | 24 | |
| GSE43470 | MAST2 | 23139 | 6 | 2 | 35 | |
| GSE46452 | MAST2 | 23139 | 2 | 1 | 56 | |
| GSE47630 | MAST2 | 23139 | 8 | 4 | 28 | |
| GSE54993 | MAST2 | 23139 | 0 | 1 | 69 | |
| GSE54994 | MAST2 | 23139 | 11 | 2 | 40 | |
| GSE60625 | MAST2 | 23139 | 0 | 0 | 11 | |
| GSE74703 | MAST2 | 23139 | 5 | 1 | 30 | |
| GSE74704 | MAST2 | 23139 | 2 | 0 | 18 | |
| TCGA | MAST2 | 23139 | 11 | 16 | 69 |
Total number of gains: 53; Total number of losses: 32; Total Number of normals: 403.
Somatic mutations of MAST2:
Generating mutation plots.
Highly correlated genes for MAST2:
Showing top 20/1069 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAST2 | SSC5D | 0.806573 | 3 | 0 | 3 |
| MAST2 | MNT | 0.799204 | 3 | 0 | 3 |
| MAST2 | RILPL1 | 0.79205 | 4 | 0 | 4 |
| MAST2 | DHDH | 0.780496 | 3 | 0 | 3 |
| MAST2 | KDM6B | 0.771358 | 3 | 0 | 3 |
| MAST2 | DAPK3 | 0.761469 | 4 | 0 | 4 |
| MAST2 | NR1H2 | 0.759059 | 3 | 0 | 3 |
| MAST2 | SARDH | 0.754333 | 4 | 0 | 4 |
| MAST2 | C16orf58 | 0.751091 | 3 | 0 | 3 |
| MAST2 | C15orf61 | 0.750733 | 3 | 0 | 3 |
| MAST2 | ZNF628 | 0.750391 | 4 | 0 | 4 |
| MAST2 | GTPBP10 | 0.746591 | 3 | 0 | 3 |
| MAST2 | TMEM150A | 0.744163 | 3 | 0 | 3 |
| MAST2 | SNTA1 | 0.739211 | 3 | 0 | 3 |
| MAST2 | FOXP4 | 0.73776 | 3 | 0 | 3 |
| MAST2 | CXCR5 | 0.734511 | 3 | 0 | 3 |
| MAST2 | ZNF584 | 0.734276 | 3 | 0 | 3 |
| MAST2 | SLC39A13 | 0.732417 | 6 | 0 | 6 |
| MAST2 | RPRD2 | 0.730788 | 3 | 0 | 3 |
| MAST2 | GDF11 | 0.729494 | 5 | 0 | 4 |
For details and further investigation, click here
