| Full name: vacuolar protein sorting 13 homolog C | Alias Symbol: FLJ20136|FLJ10381|KIAA1421 | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 54832 | HGNC ID: HGNC:23594 | Ensembl Gene: ENSG00000129003 | OMIM ID: 608879 |
| Drug and gene relationship at DGIdb | |||
Expression of VPS13C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS13C | 54832 | 218396_at | -0.0983 | 0.8846 | |
| GSE20347 | VPS13C | 54832 | 218396_at | 0.9675 | 0.0004 | |
| GSE23400 | VPS13C | 54832 | 218396_at | 0.4352 | 0.0027 | |
| GSE26886 | VPS13C | 54832 | 218396_at | 2.4394 | 0.0000 | |
| GSE29001 | VPS13C | 54832 | 218396_at | 1.0491 | 0.0024 | |
| GSE38129 | VPS13C | 54832 | 218396_at | 0.4869 | 0.0900 | |
| GSE45670 | VPS13C | 54832 | 218396_at | -0.2435 | 0.4375 | |
| GSE53622 | VPS13C | 54832 | 163464 | 0.1517 | 0.2546 | |
| GSE53624 | VPS13C | 54832 | 163464 | 0.1741 | 0.1640 | |
| GSE63941 | VPS13C | 54832 | 218396_at | -1.6013 | 0.0077 | |
| GSE77861 | VPS13C | 54832 | 218396_at | 1.7679 | 0.0006 | |
| GSE97050 | VPS13C | 54832 | A_33_P3333537 | -0.1302 | 0.6613 | |
| SRP007169 | VPS13C | 54832 | RNAseq | 2.2944 | 0.0001 | |
| SRP008496 | VPS13C | 54832 | RNAseq | 2.4216 | 0.0000 | |
| SRP064894 | VPS13C | 54832 | RNAseq | 0.3860 | 0.2180 | |
| SRP133303 | VPS13C | 54832 | RNAseq | 0.4216 | 0.0019 | |
| SRP159526 | VPS13C | 54832 | RNAseq | -0.2638 | 0.5693 | |
| SRP193095 | VPS13C | 54832 | RNAseq | 0.3024 | 0.2912 | |
| SRP219564 | VPS13C | 54832 | RNAseq | 0.4115 | 0.2425 | |
| TCGA | VPS13C | 54832 | RNAseq | -0.2853 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by VPS13C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS13C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS13C | 54832 | 7 | 3 | 20 | |
| GSE20123 | VPS13C | 54832 | 7 | 2 | 21 | |
| GSE43470 | VPS13C | 54832 | 4 | 6 | 33 | |
| GSE46452 | VPS13C | 54832 | 3 | 7 | 49 | |
| GSE47630 | VPS13C | 54832 | 8 | 10 | 22 | |
| GSE54993 | VPS13C | 54832 | 5 | 6 | 59 | |
| GSE54994 | VPS13C | 54832 | 6 | 8 | 39 | |
| GSE60625 | VPS13C | 54832 | 4 | 0 | 7 | |
| GSE74703 | VPS13C | 54832 | 4 | 3 | 29 | |
| GSE74704 | VPS13C | 54832 | 3 | 3 | 14 | |
| TCGA | VPS13C | 54832 | 10 | 17 | 69 |
Total number of gains: 61; Total number of losses: 65; Total Number of normals: 362.
Somatic mutations of VPS13C:
Generating mutation plots.
Highly correlated genes for VPS13C:
Showing top 20/1276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS13C | ZBED1 | 0.819251 | 3 | 0 | 3 |
| VPS13C | ZNF518B | 0.799967 | 3 | 0 | 3 |
| VPS13C | TP53I13 | 0.799769 | 3 | 0 | 3 |
| VPS13C | BRD9 | 0.784491 | 3 | 0 | 3 |
| VPS13C | WDR54 | 0.777611 | 3 | 0 | 3 |
| VPS13C | BRAT1 | 0.775233 | 3 | 0 | 3 |
| VPS13C | STRADA | 0.77451 | 3 | 0 | 3 |
| VPS13C | PET117 | 0.769421 | 3 | 0 | 3 |
| VPS13C | XPR1 | 0.766419 | 3 | 0 | 3 |
| VPS13C | TTL | 0.764537 | 3 | 0 | 3 |
| VPS13C | PLBD2 | 0.764471 | 3 | 0 | 3 |
| VPS13C | NEDD1 | 0.762882 | 4 | 0 | 3 |
| VPS13C | BUD31 | 0.760625 | 3 | 0 | 3 |
| VPS13C | HPS3 | 0.754945 | 3 | 0 | 3 |
| VPS13C | MRPS26 | 0.74759 | 3 | 0 | 3 |
| VPS13C | PREX1 | 0.740379 | 3 | 0 | 3 |
| VPS13C | KRTCAP2 | 0.738786 | 3 | 0 | 3 |
| VPS13C | PLIN4 | 0.736833 | 3 | 0 | 3 |
| VPS13C | COPRS | 0.73681 | 3 | 0 | 3 |
| VPS13C | WDR81 | 0.734296 | 4 | 0 | 3 |
For details and further investigation, click here
