| Full name: WD repeat domain 54 | Alias Symbol: FLJ12953 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 84058 | HGNC ID: HGNC:25770 | Ensembl Gene: ENSG00000005448 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR54 | 84058 | 225898_at | 0.9579 | 0.2506 | |
| GSE26886 | WDR54 | 84058 | 225898_at | 2.9580 | 0.0000 | |
| GSE45670 | WDR54 | 84058 | 225898_at | 1.3673 | 0.0008 | |
| GSE53622 | WDR54 | 84058 | 109654 | 1.8896 | 0.0000 | |
| GSE53624 | WDR54 | 84058 | 109654 | 2.1355 | 0.0000 | |
| GSE63941 | WDR54 | 84058 | 225898_at | 0.6367 | 0.2240 | |
| GSE77861 | WDR54 | 84058 | 225898_at | 1.2024 | 0.0167 | |
| GSE97050 | WDR54 | 84058 | A_23_P68072 | 0.3727 | 0.3332 | |
| SRP007169 | WDR54 | 84058 | RNAseq | 3.9031 | 0.0000 | |
| SRP008496 | WDR54 | 84058 | RNAseq | 3.6969 | 0.0000 | |
| SRP064894 | WDR54 | 84058 | RNAseq | 2.2154 | 0.0000 | |
| SRP133303 | WDR54 | 84058 | RNAseq | 1.5389 | 0.0000 | |
| SRP159526 | WDR54 | 84058 | RNAseq | 2.0915 | 0.0000 | |
| SRP193095 | WDR54 | 84058 | RNAseq | 1.9490 | 0.0000 | |
| SRP219564 | WDR54 | 84058 | RNAseq | 1.1585 | 0.0263 | |
| TCGA | WDR54 | 84058 | RNAseq | 0.6791 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by WDR54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR54 | 84058 | 9 | 2 | 19 | |
| GSE20123 | WDR54 | 84058 | 11 | 1 | 18 | |
| GSE43470 | WDR54 | 84058 | 4 | 0 | 39 | |
| GSE46452 | WDR54 | 84058 | 2 | 3 | 54 | |
| GSE47630 | WDR54 | 84058 | 7 | 0 | 33 | |
| GSE54993 | WDR54 | 84058 | 0 | 6 | 64 | |
| GSE54994 | WDR54 | 84058 | 10 | 0 | 43 | |
| GSE60625 | WDR54 | 84058 | 0 | 3 | 8 | |
| GSE74703 | WDR54 | 84058 | 4 | 0 | 32 | |
| GSE74704 | WDR54 | 84058 | 8 | 0 | 12 | |
| TCGA | WDR54 | 84058 | 37 | 2 | 57 |
Total number of gains: 92; Total number of losses: 17; Total Number of normals: 379.
Somatic mutations of WDR54:
Generating mutation plots.
Highly correlated genes for WDR54:
Showing top 20/2343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR54 | MYH9 | 0.882066 | 4 | 0 | 4 |
| WDR54 | KHSRP | 0.833613 | 4 | 0 | 4 |
| WDR54 | FADS1 | 0.823676 | 3 | 0 | 3 |
| WDR54 | ARPC1B | 0.822839 | 7 | 0 | 7 |
| WDR54 | VOPP1 | 0.818284 | 7 | 0 | 7 |
| WDR54 | LPCAT1 | 0.817129 | 7 | 0 | 7 |
| WDR54 | PXDN | 0.815851 | 7 | 0 | 7 |
| WDR54 | MYO5A | 0.815804 | 7 | 0 | 7 |
| WDR54 | SLC35B2 | 0.814968 | 3 | 0 | 3 |
| WDR54 | SLC39A3 | 0.81462 | 3 | 0 | 3 |
| WDR54 | LGALS8 | 0.811279 | 3 | 0 | 3 |
| WDR54 | LAMC2 | 0.810396 | 6 | 0 | 6 |
| WDR54 | INHBA | 0.808172 | 6 | 0 | 6 |
| WDR54 | TMEM184B | 0.804442 | 7 | 0 | 7 |
| WDR54 | GALNT18 | 0.80374 | 6 | 0 | 6 |
| WDR54 | TRAM2 | 0.803297 | 7 | 0 | 7 |
| WDR54 | ANGPT2 | 0.802192 | 5 | 0 | 5 |
| WDR54 | XAB2 | 0.801424 | 3 | 0 | 3 |
| WDR54 | ZNF281 | 0.801095 | 6 | 0 | 6 |
| WDR54 | LOXL2 | 0.800399 | 7 | 0 | 7 |
For details and further investigation, click here
