BRD9

 

Full name: bromodomain containing 9 Alias Symbol: FLJ13441
Type: protein-coding gene Cytoband: 5p15.33
Entrez ID: 65980 HGNC ID: HGNC:25818 Ensembl Gene: ENSG00000028310 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of BRD9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BRD9 65980 220155_s_at 0.6723 0.0519
GSE20347 BRD9 65980 220155_s_at 0.5402 0.0001
GSE23400 BRD9 65980 220155_s_at 0.3461 0.0000
GSE26886 BRD9 65980 220155_s_at 0.7419 0.0000
GSE29001 BRD9 65980 220155_s_at 0.5064 0.1107
GSE38129 BRD9 65980 220155_s_at 0.4452 0.0001
GSE45670 BRD9 65980 220155_s_at 0.3469 0.0174
GSE53622 BRD9 65980 116573 0.3764 0.0000
GSE53624 BRD9 65980 116573 0.5068 0.0000
GSE63941 BRD9 65980 220155_s_at -0.0863 0.8257
GSE77861 BRD9 65980 220155_s_at 0.3152 0.0769
GSE97050 BRD9 65980 A_23_P19004 0.3097 0.2237
SRP007169 BRD9 65980 RNAseq 1.3907 0.0034
SRP008496 BRD9 65980 RNAseq 0.9971 0.0050
SRP064894 BRD9 65980 RNAseq 0.4381 0.0013
SRP133303 BRD9 65980 RNAseq 0.5339 0.0099
SRP159526 BRD9 65980 RNAseq 0.5093 0.1275
SRP193095 BRD9 65980 RNAseq 0.6973 0.0000
SRP219564 BRD9 65980 RNAseq 0.9486 0.0549
TCGA BRD9 65980 RNAseq 0.1055 0.0855

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by BRD9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BRD9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BRD9 65980 13 1 16
GSE20123 BRD9 65980 13 1 16
GSE43470 BRD9 65980 17 1 25
GSE46452 BRD9 65980 6 22 31
GSE47630 BRD9 65980 10 10 20
GSE54993 BRD9 65980 5 6 59
GSE54994 BRD9 65980 29 1 23
GSE60625 BRD9 65980 0 0 11
GSE74703 BRD9 65980 14 0 22
GSE74704 BRD9 65980 11 0 9
TCGA BRD9 65980 60 4 32

Total number of gains: 178; Total number of losses: 46; Total Number of normals: 264.  


 

Somatic mutations of BRD9:

 

Generating mutation plots.

 

Highly correlated genes for BRD9:

 

Showing top 20/1298 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BRD9ACBD60.819314303
BRD9TSEN340.802052303
BRD9LRRC690.801713303
BRD9PDCD2L0.795819303
BRD9VPS13C0.784491303
BRD9ZNF5840.779679303
BRD9SLC36A40.771133303
BRD9SLC39A30.763842403
BRD9CCNK0.760667303
BRD9TCF7L20.759505303
BRD9SPIRE20.759015303
BRD9WDR810.756863404
BRD9SLC25A290.754309303
BRD9ICE10.752576808
BRD9SETD50.744204303
BRD9GBP50.743298303
BRD9SLC37A30.734884303
BRD9SSBP40.734719403
BRD9KCNE30.733127303
BRD9INPP4A0.732959303

For details and further investigation, click here