| Full name: STE20 related adaptor alpha | Alias Symbol: NY-BR-96|LYK5|Stlk|STRAD | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 92335 | HGNC ID: HGNC:30172 | Ensembl Gene: ENSG00000266173 | OMIM ID: 608626 |
| Drug and gene relationship at DGIdb | |||
STRADA involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway | |
| hsa04152 | AMPK signaling pathway |
Expression of STRADA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRADA | 92335 | 52169_at | 0.1992 | 0.4052 | |
| GSE20347 | STRADA | 92335 | 52169_at | 0.2000 | 0.0468 | |
| GSE23400 | STRADA | 92335 | 52169_at | 0.0635 | 0.0216 | |
| GSE26886 | STRADA | 92335 | 52169_at | 0.5175 | 0.0007 | |
| GSE29001 | STRADA | 92335 | 52169_at | -0.0401 | 0.8821 | |
| GSE38129 | STRADA | 92335 | 52169_at | 0.1486 | 0.0859 | |
| GSE45670 | STRADA | 92335 | 52169_at | 0.2471 | 0.0146 | |
| GSE63941 | STRADA | 92335 | 52169_at | -0.4968 | 0.0666 | |
| GSE77861 | STRADA | 92335 | 52169_at | 0.3441 | 0.0593 | |
| GSE97050 | STRADA | 92335 | A_24_P147407 | 0.1081 | 0.6114 | |
| SRP007169 | STRADA | 92335 | RNAseq | 0.1607 | 0.6975 | |
| SRP008496 | STRADA | 92335 | RNAseq | 0.2583 | 0.4108 | |
| SRP064894 | STRADA | 92335 | RNAseq | 0.2497 | 0.0450 | |
| SRP133303 | STRADA | 92335 | RNAseq | -0.0031 | 0.9819 | |
| SRP159526 | STRADA | 92335 | RNAseq | 0.1566 | 0.4428 | |
| SRP193095 | STRADA | 92335 | RNAseq | 0.0535 | 0.6188 | |
| SRP219564 | STRADA | 92335 | RNAseq | 0.0712 | 0.7430 | |
| TCGA | STRADA | 92335 | RNAseq | -0.0145 | 0.7869 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STRADA expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of STRADA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRADA | 92335 | 3 | 1 | 26 | |
| GSE20123 | STRADA | 92335 | 3 | 1 | 26 | |
| GSE43470 | STRADA | 92335 | 4 | 0 | 39 | |
| GSE46452 | STRADA | 92335 | 31 | 0 | 28 | |
| GSE47630 | STRADA | 92335 | 7 | 1 | 32 | |
| GSE54993 | STRADA | 92335 | 2 | 5 | 63 | |
| GSE54994 | STRADA | 92335 | 9 | 4 | 40 | |
| GSE60625 | STRADA | 92335 | 4 | 0 | 7 | |
| GSE74703 | STRADA | 92335 | 4 | 0 | 32 | |
| GSE74704 | STRADA | 92335 | 3 | 1 | 16 | |
| TCGA | STRADA | 92335 | 31 | 9 | 56 |
Total number of gains: 101; Total number of losses: 22; Total Number of normals: 365.
Somatic mutations of STRADA:
Generating mutation plots.
Highly correlated genes for STRADA:
Showing top 20/877 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRADA | INPP5E | 0.823354 | 3 | 0 | 3 |
| STRADA | TBP | 0.784871 | 3 | 0 | 3 |
| STRADA | ECSIT | 0.775243 | 3 | 0 | 3 |
| STRADA | VPS13C | 0.77451 | 3 | 0 | 3 |
| STRADA | PLEKHA3 | 0.774071 | 3 | 0 | 3 |
| STRADA | ABI2 | 0.768771 | 3 | 0 | 3 |
| STRADA | SPOCK1 | 0.760252 | 4 | 0 | 4 |
| STRADA | TBCB | 0.759879 | 3 | 0 | 3 |
| STRADA | ALKBH6 | 0.758607 | 4 | 0 | 3 |
| STRADA | FAM53B | 0.753392 | 3 | 0 | 3 |
| STRADA | INPP5B | 0.753144 | 3 | 0 | 3 |
| STRADA | TBC1D25 | 0.751204 | 3 | 0 | 3 |
| STRADA | DGKH | 0.750983 | 3 | 0 | 3 |
| STRADA | NARF | 0.747412 | 3 | 0 | 3 |
| STRADA | THAP5 | 0.747374 | 3 | 0 | 3 |
| STRADA | FTO | 0.746045 | 3 | 0 | 3 |
| STRADA | CCDC144A | 0.744583 | 3 | 0 | 3 |
| STRADA | TCF7L1 | 0.740183 | 3 | 0 | 3 |
| STRADA | ZNF518B | 0.739587 | 3 | 0 | 3 |
| STRADA | GNA13 | 0.737511 | 5 | 0 | 5 |
For details and further investigation, click here
