| Full name: WD repeat domain 45 | Alias Symbol: JM5|WIPI4|NBIA5 | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 11152 | HGNC ID: HGNC:28912 | Ensembl Gene: ENSG00000196998 | OMIM ID: 300526 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR45:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR45 | 11152 | 209216_at | -0.0044 | 0.9955 | |
| GSE20347 | WDR45 | 11152 | 209216_at | -0.2327 | 0.2581 | |
| GSE23400 | WDR45 | 11152 | 209216_at | -0.0322 | 0.6187 | |
| GSE26886 | WDR45 | 11152 | 209216_at | 0.2492 | 0.4184 | |
| GSE29001 | WDR45 | 11152 | 209216_at | -0.3018 | 0.3340 | |
| GSE38129 | WDR45 | 11152 | 209216_at | -0.1473 | 0.4501 | |
| GSE45670 | WDR45 | 11152 | 209216_at | 0.0372 | 0.8717 | |
| GSE53622 | WDR45 | 11152 | 77114 | -0.0936 | 0.2119 | |
| GSE53624 | WDR45 | 11152 | 77114 | -0.1030 | 0.1264 | |
| GSE63941 | WDR45 | 11152 | 209216_at | -1.2803 | 0.0335 | |
| GSE77861 | WDR45 | 11152 | 209217_s_at | -0.2414 | 0.2543 | |
| GSE97050 | WDR45 | 11152 | A_33_P3228591 | -0.2273 | 0.2991 | |
| SRP007169 | WDR45 | 11152 | RNAseq | -1.1888 | 0.0094 | |
| SRP008496 | WDR45 | 11152 | RNAseq | -0.9580 | 0.0003 | |
| SRP064894 | WDR45 | 11152 | RNAseq | 0.1617 | 0.4643 | |
| SRP133303 | WDR45 | 11152 | RNAseq | -0.0681 | 0.7091 | |
| SRP159526 | WDR45 | 11152 | RNAseq | 0.0931 | 0.5864 | |
| SRP193095 | WDR45 | 11152 | RNAseq | -0.0954 | 0.4004 | |
| SRP219564 | WDR45 | 11152 | RNAseq | -0.0481 | 0.8513 | |
| TCGA | WDR45 | 11152 | RNAseq | -0.1208 | 0.0288 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by WDR45 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR45:
No record found for this gene.
Somatic mutations of WDR45:
Generating mutation plots.
Highly correlated genes for WDR45:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR45 | GPR17 | 0.764018 | 3 | 0 | 3 |
| WDR45 | ZBTB45 | 0.735752 | 3 | 0 | 3 |
| WDR45 | UCK1 | 0.707267 | 4 | 0 | 4 |
| WDR45 | C16orf89 | 0.700576 | 3 | 0 | 3 |
| WDR45 | USP27X | 0.697283 | 5 | 0 | 5 |
| WDR45 | GRIPAP1 | 0.687951 | 6 | 0 | 5 |
| WDR45 | SPIN1 | 0.686337 | 3 | 0 | 3 |
| WDR45 | TRIM31 | 0.684269 | 3 | 0 | 3 |
| WDR45 | ZNF576 | 0.68024 | 4 | 0 | 3 |
| WDR45 | WDR60 | 0.678491 | 3 | 0 | 3 |
| WDR45 | BEND7 | 0.674846 | 5 | 0 | 3 |
| WDR45 | DMGDH | 0.671362 | 3 | 0 | 3 |
| WDR45 | SETD1B | 0.671119 | 4 | 0 | 3 |
| WDR45 | ATF7IP2 | 0.639532 | 4 | 0 | 3 |
| WDR45 | CCDC22 | 0.633332 | 10 | 0 | 7 |
| WDR45 | ALKBH2 | 0.632605 | 3 | 0 | 3 |
| WDR45 | ZNF182 | 0.629471 | 5 | 0 | 4 |
| WDR45 | SUN2 | 0.624537 | 4 | 0 | 3 |
| WDR45 | TMEM120B | 0.620846 | 4 | 0 | 3 |
| WDR45 | ZNF48 | 0.604854 | 5 | 0 | 3 |
For details and further investigation, click here
