| Full name: WD repeat domain 60 | Alias Symbol: FLJ10300|FAP163 | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 55112 | HGNC ID: HGNC:21862 | Ensembl Gene: ENSG00000126870 | OMIM ID: 615462 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR60:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR60 | 55112 | 219251_s_at | -0.6811 | 0.1057 | |
| GSE20347 | WDR60 | 55112 | 219251_s_at | -0.0390 | 0.7836 | |
| GSE23400 | WDR60 | 55112 | 219251_s_at | -0.1377 | 0.0024 | |
| GSE26886 | WDR60 | 55112 | 219251_s_at | 0.0349 | 0.8838 | |
| GSE29001 | WDR60 | 55112 | 219251_s_at | -0.0712 | 0.7979 | |
| GSE38129 | WDR60 | 55112 | 219251_s_at | -0.1871 | 0.0709 | |
| GSE45670 | WDR60 | 55112 | 219251_s_at | -0.4170 | 0.0006 | |
| GSE53622 | WDR60 | 55112 | 53960 | -0.2901 | 0.0004 | |
| GSE53624 | WDR60 | 55112 | 53960 | -0.1641 | 0.0193 | |
| GSE63941 | WDR60 | 55112 | 219251_s_at | -1.1007 | 0.0014 | |
| GSE77861 | WDR60 | 55112 | 219251_s_at | -0.0670 | 0.8021 | |
| GSE97050 | WDR60 | 55112 | A_33_P3349927 | 0.0983 | 0.6238 | |
| SRP007169 | WDR60 | 55112 | RNAseq | 1.0569 | 0.1172 | |
| SRP064894 | WDR60 | 55112 | RNAseq | -0.2793 | 0.0999 | |
| SRP133303 | WDR60 | 55112 | RNAseq | -0.2928 | 0.0266 | |
| SRP159526 | WDR60 | 55112 | RNAseq | -0.6668 | 0.0532 | |
| SRP193095 | WDR60 | 55112 | RNAseq | 0.2132 | 0.1715 | |
| SRP219564 | WDR60 | 55112 | RNAseq | -0.3944 | 0.3542 | |
| TCGA | WDR60 | 55112 | RNAseq | -0.3061 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WDR60 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR60:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR60 | 55112 | 3 | 3 | 24 | |
| GSE20123 | WDR60 | 55112 | 2 | 3 | 25 | |
| GSE43470 | WDR60 | 55112 | 2 | 5 | 36 | |
| GSE46452 | WDR60 | 55112 | 7 | 2 | 50 | |
| GSE47630 | WDR60 | 55112 | 6 | 9 | 25 | |
| GSE54993 | WDR60 | 55112 | 3 | 3 | 64 | |
| GSE54994 | WDR60 | 55112 | 8 | 9 | 36 | |
| GSE60625 | WDR60 | 55112 | 0 | 0 | 11 | |
| GSE74703 | WDR60 | 55112 | 2 | 4 | 30 | |
| GSE74704 | WDR60 | 55112 | 1 | 3 | 16 | |
| TCGA | WDR60 | 55112 | 28 | 26 | 42 |
Total number of gains: 62; Total number of losses: 67; Total Number of normals: 359.
Somatic mutations of WDR60:
Generating mutation plots.
Highly correlated genes for WDR60:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR60 | KLK2 | 0.792787 | 3 | 0 | 3 |
| WDR60 | NRF1 | 0.753969 | 3 | 0 | 3 |
| WDR60 | TRIM17 | 0.75025 | 3 | 0 | 3 |
| WDR60 | TMEM101 | 0.74106 | 3 | 0 | 3 |
| WDR60 | CDHR2 | 0.728318 | 3 | 0 | 3 |
| WDR60 | IRGQ | 0.716946 | 3 | 0 | 3 |
| WDR60 | LAMTOR2 | 0.715114 | 3 | 0 | 3 |
| WDR60 | ZMYND10 | 0.711051 | 3 | 0 | 3 |
| WDR60 | CCDC89 | 0.708235 | 3 | 0 | 3 |
| WDR60 | KRT35 | 0.707912 | 3 | 0 | 3 |
| WDR60 | CYB561D1 | 0.702979 | 3 | 0 | 3 |
| WDR60 | CNTN4 | 0.69583 | 4 | 0 | 4 |
| WDR60 | CDC34 | 0.692808 | 3 | 0 | 3 |
| WDR60 | SCARA5 | 0.690712 | 3 | 0 | 3 |
| WDR60 | NCR3 | 0.690589 | 3 | 0 | 3 |
| WDR60 | LMAN1L | 0.690491 | 3 | 0 | 3 |
| WDR60 | DRD4 | 0.687413 | 3 | 0 | 3 |
| WDR60 | FAM219B | 0.682872 | 3 | 0 | 3 |
| WDR60 | GPR146 | 0.682117 | 3 | 0 | 3 |
| WDR60 | TBX4 | 0.680978 | 3 | 0 | 3 |
For details and further investigation, click here
