| Full name: transmembrane protein 120B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 144404 | HGNC ID: HGNC:32008 | Ensembl Gene: ENSG00000188735 | OMIM ID: 616551 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM120B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM120B | 144404 | 219154_at | 0.4930 | 0.3526 | |
| GSE20347 | TMEM120B | 144404 | 219154_at | 0.0946 | 0.1750 | |
| GSE23400 | TMEM120B | 144404 | 219154_at | -0.0935 | 0.0420 | |
| GSE26886 | TMEM120B | 144404 | 219154_at | 0.4111 | 0.0558 | |
| GSE29001 | TMEM120B | 144404 | 219154_at | 0.0839 | 0.6121 | |
| GSE38129 | TMEM120B | 144404 | 219154_at | -0.0239 | 0.8363 | |
| GSE45670 | TMEM120B | 144404 | 219154_at | 0.0964 | 0.5998 | |
| GSE53622 | TMEM120B | 144404 | 16674 | 0.4832 | 0.0000 | |
| GSE53624 | TMEM120B | 144404 | 153859 | 0.5322 | 0.0000 | |
| GSE63941 | TMEM120B | 144404 | 219154_at | -0.1873 | 0.6695 | |
| GSE77861 | TMEM120B | 144404 | 219154_at | 0.0864 | 0.4624 | |
| GSE97050 | TMEM120B | 144404 | A_33_P3388482 | 0.1202 | 0.7144 | |
| SRP007169 | TMEM120B | 144404 | RNAseq | -0.3497 | 0.4141 | |
| SRP008496 | TMEM120B | 144404 | RNAseq | -0.5205 | 0.0489 | |
| SRP064894 | TMEM120B | 144404 | RNAseq | 0.3069 | 0.0354 | |
| SRP133303 | TMEM120B | 144404 | RNAseq | 0.1554 | 0.1794 | |
| SRP159526 | TMEM120B | 144404 | RNAseq | 0.4318 | 0.1418 | |
| SRP193095 | TMEM120B | 144404 | RNAseq | 0.2410 | 0.0280 | |
| SRP219564 | TMEM120B | 144404 | RNAseq | 0.3374 | 0.3414 | |
| TCGA | TMEM120B | 144404 | RNAseq | -0.1717 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM120B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM120B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM120B | 144404 | 5 | 4 | 21 | |
| GSE20123 | TMEM120B | 144404 | 5 | 4 | 21 | |
| GSE43470 | TMEM120B | 144404 | 2 | 2 | 39 | |
| GSE46452 | TMEM120B | 144404 | 9 | 1 | 49 | |
| GSE47630 | TMEM120B | 144404 | 9 | 3 | 28 | |
| GSE54993 | TMEM120B | 144404 | 0 | 5 | 65 | |
| GSE54994 | TMEM120B | 144404 | 6 | 7 | 40 | |
| GSE60625 | TMEM120B | 144404 | 0 | 0 | 11 | |
| GSE74703 | TMEM120B | 144404 | 2 | 1 | 33 | |
| GSE74704 | TMEM120B | 144404 | 4 | 2 | 14 | |
| TCGA | TMEM120B | 144404 | 21 | 10 | 65 |
Total number of gains: 63; Total number of losses: 39; Total Number of normals: 386.
Somatic mutations of TMEM120B:
Generating mutation plots.
Highly correlated genes for TMEM120B:
Showing top 20/164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM120B | TAF5L | 0.819568 | 3 | 0 | 3 |
| TMEM120B | FAM24B | 0.784826 | 3 | 0 | 3 |
| TMEM120B | GABRB1 | 0.778627 | 3 | 0 | 3 |
| TMEM120B | GPAT2 | 0.766445 | 3 | 0 | 3 |
| TMEM120B | HRK | 0.734334 | 3 | 0 | 3 |
| TMEM120B | ZNF157 | 0.728833 | 3 | 0 | 3 |
| TMEM120B | DOHH | 0.727634 | 5 | 0 | 5 |
| TMEM120B | C7orf61 | 0.714802 | 3 | 0 | 3 |
| TMEM120B | SMARCB1 | 0.707605 | 3 | 0 | 3 |
| TMEM120B | STK32C | 0.700912 | 4 | 0 | 4 |
| TMEM120B | HOTAIR | 0.697494 | 3 | 0 | 3 |
| TMEM120B | NTNG2 | 0.693935 | 3 | 0 | 3 |
| TMEM120B | PTPRH | 0.69103 | 3 | 0 | 3 |
| TMEM120B | TRIM11 | 0.689086 | 3 | 0 | 3 |
| TMEM120B | DPM3 | 0.688917 | 5 | 0 | 4 |
| TMEM120B | CC2D1B | 0.679684 | 3 | 0 | 3 |
| TMEM120B | NAT14 | 0.674518 | 4 | 0 | 4 |
| TMEM120B | PRPF31 | 0.673975 | 4 | 0 | 3 |
| TMEM120B | WDR83 | 0.673519 | 4 | 0 | 3 |
| TMEM120B | SCN2A | 0.670029 | 3 | 0 | 3 |
For details and further investigation, click here
