| Full name: zinc finger protein 576 | Alias Symbol: MGC2508 | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 79177 | HGNC ID: HGNC:28357 | Ensembl Gene: ENSG00000124444 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF576:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF576 | 79177 | 219088_s_at | 0.1408 | 0.7870 | |
| GSE20347 | ZNF576 | 79177 | 219089_s_at | 0.1148 | 0.1961 | |
| GSE23400 | ZNF576 | 79177 | 219089_s_at | 0.0111 | 0.7027 | |
| GSE26886 | ZNF576 | 79177 | 219089_s_at | 0.1459 | 0.3439 | |
| GSE29001 | ZNF576 | 79177 | 219089_s_at | 0.1472 | 0.3743 | |
| GSE38129 | ZNF576 | 79177 | 219089_s_at | -0.0566 | 0.3494 | |
| GSE45670 | ZNF576 | 79177 | 219089_s_at | 0.1287 | 0.1543 | |
| GSE53622 | ZNF576 | 79177 | 6639 | 0.0100 | 0.9089 | |
| GSE53624 | ZNF576 | 79177 | 6639 | 0.2419 | 0.0043 | |
| GSE63941 | ZNF576 | 79177 | 219089_s_at | 0.0164 | 0.9481 | |
| GSE77861 | ZNF576 | 79177 | 219089_s_at | -0.0101 | 0.9108 | |
| GSE97050 | ZNF576 | 79177 | A_24_P293120 | -0.3188 | 0.2483 | |
| SRP007169 | ZNF576 | 79177 | RNAseq | -0.3503 | 0.4759 | |
| SRP008496 | ZNF576 | 79177 | RNAseq | -0.0439 | 0.8867 | |
| SRP064894 | ZNF576 | 79177 | RNAseq | 0.3951 | 0.1425 | |
| SRP133303 | ZNF576 | 79177 | RNAseq | 0.1062 | 0.4092 | |
| SRP159526 | ZNF576 | 79177 | RNAseq | 0.4441 | 0.1154 | |
| SRP193095 | ZNF576 | 79177 | RNAseq | -0.0329 | 0.6709 | |
| SRP219564 | ZNF576 | 79177 | RNAseq | 0.0458 | 0.8602 | |
| TCGA | ZNF576 | 79177 | RNAseq | 0.0292 | 0.6870 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF576 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF576:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF576 | 79177 | 6 | 5 | 19 | |
| GSE20123 | ZNF576 | 79177 | 5 | 4 | 21 | |
| GSE43470 | ZNF576 | 79177 | 4 | 11 | 28 | |
| GSE46452 | ZNF576 | 79177 | 45 | 1 | 13 | |
| GSE47630 | ZNF576 | 79177 | 8 | 6 | 26 | |
| GSE54993 | ZNF576 | 79177 | 17 | 4 | 49 | |
| GSE54994 | ZNF576 | 79177 | 6 | 12 | 35 | |
| GSE60625 | ZNF576 | 79177 | 9 | 0 | 2 | |
| GSE74703 | ZNF576 | 79177 | 4 | 7 | 25 | |
| GSE74704 | ZNF576 | 79177 | 4 | 2 | 14 | |
| TCGA | ZNF576 | 79177 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 68; Total Number of normals: 298.
Somatic mutations of ZNF576:
Generating mutation plots.
Highly correlated genes for ZNF576:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF576 | FAM189B | 0.72706 | 3 | 0 | 3 |
| ZNF576 | STK32C | 0.719959 | 3 | 0 | 3 |
| ZNF576 | FUZ | 0.704674 | 4 | 0 | 4 |
| ZNF576 | MAGEL2 | 0.697033 | 4 | 0 | 4 |
| ZNF576 | TNXB | 0.688682 | 3 | 0 | 3 |
| ZNF576 | NEURL2 | 0.68465 | 3 | 0 | 3 |
| ZNF576 | TP53BP1 | 0.68299 | 4 | 0 | 3 |
| ZNF576 | TMEM182 | 0.682858 | 3 | 0 | 3 |
| ZNF576 | WDR45 | 0.68024 | 4 | 0 | 3 |
| ZNF576 | USP27X | 0.672411 | 3 | 0 | 3 |
| ZNF576 | LAT | 0.662421 | 4 | 0 | 3 |
| ZNF576 | MEX3D | 0.656489 | 3 | 0 | 3 |
| ZNF576 | FBXL15 | 0.653953 | 5 | 0 | 4 |
| ZNF576 | PLXNA3 | 0.644284 | 3 | 0 | 3 |
| ZNF576 | PPP2R5D | 0.642917 | 4 | 0 | 3 |
| ZNF576 | SDHAF1 | 0.634033 | 6 | 0 | 4 |
| ZNF576 | C16orf95 | 0.632579 | 3 | 0 | 3 |
| ZNF576 | DGKZ | 0.632437 | 3 | 0 | 3 |
| ZNF576 | POMT2 | 0.630358 | 4 | 0 | 4 |
| ZNF576 | ZNF48 | 0.628443 | 4 | 0 | 3 |
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