| Full name: G protein-coupled receptor 17 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 2840 | HGNC ID: HGNC:4471 | Ensembl Gene: ENSG00000144230 | OMIM ID: 603071 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR17 | 2840 | 215225_s_at | 0.0275 | 0.9367 | |
| GSE20347 | GPR17 | 2840 | 215225_s_at | -0.0568 | 0.3990 | |
| GSE23400 | GPR17 | 2840 | 215225_s_at | -0.1197 | 0.0004 | |
| GSE26886 | GPR17 | 2840 | 215225_s_at | 0.1359 | 0.2020 | |
| GSE29001 | GPR17 | 2840 | 215225_s_at | -0.1853 | 0.0582 | |
| GSE38129 | GPR17 | 2840 | 215225_s_at | -0.1649 | 0.0075 | |
| GSE45670 | GPR17 | 2840 | 215225_s_at | -0.0055 | 0.9614 | |
| GSE53622 | GPR17 | 2840 | 20309 | -0.1285 | 0.1810 | |
| GSE53624 | GPR17 | 2840 | 20309 | -0.0334 | 0.5960 | |
| GSE63941 | GPR17 | 2840 | 215225_s_at | 0.1916 | 0.2123 | |
| GSE77861 | GPR17 | 2840 | 215225_s_at | -0.1912 | 0.1526 | |
| GSE97050 | GPR17 | 2840 | A_33_P3365034 | -0.2516 | 0.4731 | |
| SRP133303 | GPR17 | 2840 | RNAseq | -0.9953 | 0.0765 | |
| SRP159526 | GPR17 | 2840 | RNAseq | -1.1471 | 0.0904 | |
| SRP219564 | GPR17 | 2840 | RNAseq | -0.1994 | 0.8213 | |
| TCGA | GPR17 | 2840 | RNAseq | -1.8886 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GPR17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR17 | 2840 | 6 | 3 | 21 | |
| GSE20123 | GPR17 | 2840 | 6 | 3 | 21 | |
| GSE43470 | GPR17 | 2840 | 2 | 1 | 40 | |
| GSE46452 | GPR17 | 2840 | 1 | 3 | 55 | |
| GSE47630 | GPR17 | 2840 | 6 | 0 | 34 | |
| GSE54993 | GPR17 | 2840 | 0 | 6 | 64 | |
| GSE54994 | GPR17 | 2840 | 11 | 0 | 42 | |
| GSE60625 | GPR17 | 2840 | 0 | 3 | 8 | |
| GSE74703 | GPR17 | 2840 | 2 | 1 | 33 | |
| GSE74704 | GPR17 | 2840 | 3 | 1 | 16 | |
| TCGA | GPR17 | 2840 | 22 | 8 | 66 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of GPR17:
Generating mutation plots.
Highly correlated genes for GPR17:
Showing top 20/849 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR17 | WDR45 | 0.764018 | 3 | 0 | 3 |
| GPR17 | UMODL1 | 0.745549 | 3 | 0 | 3 |
| GPR17 | CELF4 | 0.733454 | 3 | 0 | 3 |
| GPR17 | SLC2A2 | 0.732863 | 3 | 0 | 3 |
| GPR17 | DKK4 | 0.727438 | 3 | 0 | 3 |
| GPR17 | AZU1 | 0.701015 | 4 | 0 | 4 |
| GPR17 | PPM1J | 0.695937 | 4 | 0 | 4 |
| GPR17 | TGM6 | 0.694999 | 4 | 0 | 3 |
| GPR17 | CRHR2 | 0.694728 | 4 | 0 | 4 |
| GPR17 | ACTR8 | 0.68872 | 4 | 0 | 4 |
| GPR17 | MECR | 0.688092 | 4 | 0 | 4 |
| GPR17 | BMP8B | 0.687407 | 3 | 0 | 3 |
| GPR17 | TSGA10 | 0.686882 | 3 | 0 | 3 |
| GPR17 | PHF7 | 0.685758 | 6 | 0 | 6 |
| GPR17 | MYO1A | 0.682476 | 5 | 0 | 5 |
| GPR17 | KCNMB2 | 0.681115 | 4 | 0 | 3 |
| GPR17 | A4GNT | 0.681038 | 3 | 0 | 3 |
| GPR17 | LMAN1L | 0.679796 | 6 | 0 | 6 |
| GPR17 | KRTAP5-9 | 0.679533 | 5 | 0 | 5 |
| GPR17 | DNMT3L | 0.675171 | 5 | 0 | 5 |
For details and further investigation, click here
