| Full name: chromosome 16 open reading frame 89 | Alias Symbol: MGC45438 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 146556 | HGNC ID: HGNC:28687 | Ensembl Gene: ENSG00000153446 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C16orf89:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C16orf89 | 146556 | 229177_at | -0.9830 | 0.0620 | |
| GSE26886 | C16orf89 | 146556 | 229177_at | 0.1594 | 0.2511 | |
| GSE45670 | C16orf89 | 146556 | 229177_at | -1.4554 | 0.0000 | |
| GSE53622 | C16orf89 | 146556 | 5735 | -1.2330 | 0.0000 | |
| GSE53624 | C16orf89 | 146556 | 5735 | -1.2885 | 0.0000 | |
| GSE63941 | C16orf89 | 146556 | 229177_at | -0.6360 | 0.0070 | |
| GSE77861 | C16orf89 | 146556 | 229177_at | -0.1169 | 0.1625 | |
| GSE97050 | C16orf89 | 146556 | A_33_P3296862 | -0.1941 | 0.4466 | |
| SRP064894 | C16orf89 | 146556 | RNAseq | -1.4382 | 0.0173 | |
| SRP133303 | C16orf89 | 146556 | RNAseq | -1.8642 | 0.0000 | |
| SRP159526 | C16orf89 | 146556 | RNAseq | -2.5025 | 0.0000 | |
| SRP219564 | C16orf89 | 146556 | RNAseq | -0.9259 | 0.3221 | |
| TCGA | C16orf89 | 146556 | RNAseq | -4.1639 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by C16orf89 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C16orf89:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C16orf89 | 146556 | 5 | 4 | 21 | |
| GSE20123 | C16orf89 | 146556 | 6 | 3 | 21 | |
| GSE43470 | C16orf89 | 146556 | 4 | 4 | 35 | |
| GSE46452 | C16orf89 | 146556 | 38 | 1 | 20 | |
| GSE47630 | C16orf89 | 146556 | 13 | 6 | 21 | |
| GSE54993 | C16orf89 | 146556 | 3 | 5 | 62 | |
| GSE54994 | C16orf89 | 146556 | 5 | 9 | 39 | |
| GSE60625 | C16orf89 | 146556 | 4 | 0 | 7 | |
| GSE74703 | C16orf89 | 146556 | 4 | 4 | 28 | |
| GSE74704 | C16orf89 | 146556 | 3 | 2 | 15 | |
| TCGA | C16orf89 | 146556 | 19 | 13 | 64 |
Total number of gains: 104; Total number of losses: 51; Total Number of normals: 333.
Somatic mutations of C16orf89:
Generating mutation plots.
Highly correlated genes for C16orf89:
Showing top 20/330 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C16orf89 | GPR146 | 0.818453 | 3 | 0 | 3 |
| C16orf89 | MAGEE2 | 0.780317 | 3 | 0 | 3 |
| C16orf89 | IL17D | 0.776915 | 3 | 0 | 3 |
| C16orf89 | SCN3A | 0.776516 | 3 | 0 | 3 |
| C16orf89 | TPO | 0.769846 | 3 | 0 | 3 |
| C16orf89 | LRRC2 | 0.767819 | 4 | 0 | 4 |
| C16orf89 | TAS2R14 | 0.763674 | 3 | 0 | 3 |
| C16orf89 | MYL4 | 0.763537 | 3 | 0 | 3 |
| C16orf89 | GALNT9 | 0.762808 | 3 | 0 | 3 |
| C16orf89 | TM6SF1 | 0.762346 | 3 | 0 | 3 |
| C16orf89 | LTC4S | 0.75599 | 3 | 0 | 3 |
| C16orf89 | HMGB4 | 0.752419 | 3 | 0 | 3 |
| C16orf89 | ADRA2A | 0.747668 | 3 | 0 | 3 |
| C16orf89 | MAGI2-AS3 | 0.746712 | 4 | 0 | 4 |
| C16orf89 | ZC3H6 | 0.745659 | 4 | 0 | 3 |
| C16orf89 | ZFPM2 | 0.744284 | 3 | 0 | 3 |
| C16orf89 | OR2Z1 | 0.744205 | 3 | 0 | 3 |
| C16orf89 | ZBTB47 | 0.744002 | 3 | 0 | 3 |
| C16orf89 | FBLN7 | 0.743489 | 3 | 0 | 3 |
| C16orf89 | FAM163B | 0.736788 | 3 | 0 | 3 |
For details and further investigation, click here
