| Full name: Sad1 and UNC84 domain containing 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 25777 | HGNC ID: HGNC:14210 | Ensembl Gene: ENSG00000100242 | OMIM ID: 613569 |
| Drug and gene relationship at DGIdb | |||
Expression of SUN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUN2 | 25777 | 212144_at | -0.1813 | 0.6483 | |
| GSE20347 | SUN2 | 25777 | 212144_at | -0.5060 | 0.0000 | |
| GSE23400 | SUN2 | 25777 | 212144_at | -0.2990 | 0.0000 | |
| GSE26886 | SUN2 | 25777 | 212144_at | -0.2461 | 0.2216 | |
| GSE29001 | SUN2 | 25777 | 212144_at | -0.3834 | 0.1506 | |
| GSE38129 | SUN2 | 25777 | 212144_at | -0.5582 | 0.0000 | |
| GSE45670 | SUN2 | 25777 | 212144_at | -0.3925 | 0.0010 | |
| GSE53622 | SUN2 | 25777 | 155200 | -0.2804 | 0.0000 | |
| GSE53624 | SUN2 | 25777 | 155200 | -0.4531 | 0.0000 | |
| GSE63941 | SUN2 | 25777 | 212144_at | 0.0858 | 0.8695 | |
| GSE77861 | SUN2 | 25777 | 212144_at | -0.3424 | 0.0269 | |
| GSE97050 | SUN2 | 25777 | A_32_P194115 | -0.2185 | 0.3727 | |
| SRP007169 | SUN2 | 25777 | RNAseq | -1.6008 | 0.0002 | |
| SRP008496 | SUN2 | 25777 | RNAseq | -1.4093 | 0.0000 | |
| SRP064894 | SUN2 | 25777 | RNAseq | -0.1107 | 0.4821 | |
| SRP133303 | SUN2 | 25777 | RNAseq | -0.5462 | 0.0001 | |
| SRP159526 | SUN2 | 25777 | RNAseq | -0.1234 | 0.6668 | |
| SRP193095 | SUN2 | 25777 | RNAseq | -0.0590 | 0.6286 | |
| SRP219564 | SUN2 | 25777 | RNAseq | -0.4771 | 0.2499 | |
| TCGA | SUN2 | 25777 | RNAseq | -0.0962 | 0.0542 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SUN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUN2 | 25777 | 6 | 5 | 19 | |
| GSE20123 | SUN2 | 25777 | 6 | 4 | 20 | |
| GSE43470 | SUN2 | 25777 | 5 | 5 | 33 | |
| GSE46452 | SUN2 | 25777 | 32 | 2 | 25 | |
| GSE47630 | SUN2 | 25777 | 9 | 4 | 27 | |
| GSE54993 | SUN2 | 25777 | 3 | 6 | 61 | |
| GSE54994 | SUN2 | 25777 | 9 | 7 | 37 | |
| GSE60625 | SUN2 | 25777 | 5 | 0 | 6 | |
| GSE74703 | SUN2 | 25777 | 5 | 4 | 27 | |
| GSE74704 | SUN2 | 25777 | 3 | 2 | 15 | |
| TCGA | SUN2 | 25777 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of SUN2:
Generating mutation plots.
Highly correlated genes for SUN2:
Showing top 20/310 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUN2 | MAGIX | 0.798969 | 3 | 0 | 3 |
| SUN2 | SYNGAP1 | 0.756414 | 3 | 0 | 3 |
| SUN2 | LMAN1L | 0.754835 | 3 | 0 | 3 |
| SUN2 | ISLR2 | 0.744503 | 3 | 0 | 3 |
| SUN2 | TERT | 0.741472 | 4 | 0 | 4 |
| SUN2 | OR10G8 | 0.721244 | 3 | 0 | 3 |
| SUN2 | TMEM217 | 0.71214 | 3 | 0 | 3 |
| SUN2 | TUSC1 | 0.709225 | 3 | 0 | 3 |
| SUN2 | LENG1 | 0.709128 | 3 | 0 | 3 |
| SUN2 | LRRC3 | 0.706476 | 4 | 0 | 3 |
| SUN2 | CLSTN3 | 0.705129 | 3 | 0 | 3 |
| SUN2 | KCNA7 | 0.701976 | 3 | 0 | 3 |
| SUN2 | CHD5 | 0.70165 | 4 | 0 | 3 |
| SUN2 | TSSK3 | 0.700876 | 3 | 0 | 3 |
| SUN2 | ZCCHC18 | 0.69812 | 5 | 0 | 4 |
| SUN2 | ASMTL | 0.691356 | 4 | 0 | 3 |
| SUN2 | COX4I2 | 0.687971 | 3 | 0 | 3 |
| SUN2 | KCNJ13 | 0.682561 | 4 | 0 | 3 |
| SUN2 | ZCWPW1 | 0.68222 | 4 | 0 | 3 |
| SUN2 | TTC39A | 0.679289 | 4 | 0 | 3 |
For details and further investigation, click here
