WFDC10A

 

Full name: WAP four-disulfide core domain 10A Alias Symbol: dJ688G8.3|WAP10
Type: protein-coding gene Cytoband: 20q13.12
Entrez ID: 140832 HGNC ID: HGNC:16139 Ensembl Gene: ENSG00000180305 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of WFDC10A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WFDC10A 140832 233913_at -0.1461 0.4704
GSE26886 WFDC10A 140832 233913_at 0.0049 0.9714
GSE45670 WFDC10A 140832 233913_at -0.0083 0.9328
GSE53622 WFDC10A 140832 35788 0.1207 0.1325
GSE53624 WFDC10A 140832 35788 0.0386 0.5585
GSE63941 WFDC10A 140832 233913_at 0.0134 0.9338
GSE77861 WFDC10A 140832 233913_at -0.2275 0.1930

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by WFDC10A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of WFDC10A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WFDC10A 140832 14 1 15
GSE20123 WFDC10A 140832 14 1 15
GSE43470 WFDC10A 140832 12 1 30
GSE46452 WFDC10A 140832 29 0 30
GSE47630 WFDC10A 140832 24 1 15
GSE54993 WFDC10A 140832 0 17 53
GSE54994 WFDC10A 140832 25 0 28
GSE60625 WFDC10A 140832 0 0 11
GSE74703 WFDC10A 140832 10 1 25
GSE74704 WFDC10A 140832 10 0 10
TCGA WFDC10A 140832 45 3 48

Total number of gains: 183; Total number of losses: 25; Total Number of normals: 280.  


 

Somatic mutations of WFDC10A:

 

Generating mutation plots.

 

Highly correlated genes for WFDC10A:

 

Showing all 16 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WFDC10ATRIM30.671847303
WFDC10APLXNA40.661864303
WFDC10AC20orf1730.646309403
WFDC10APIWIL20.623335303
WFDC10ACCL240.604892303
WFDC10ADIO3OS0.57434403
WFDC10ATFAP2B0.572412303
WFDC10ALGALS120.560023303
WFDC10ALINC012260.54843404
WFDC10ATAS2R70.542277303
WFDC10AG6PC20.541913403
WFDC10AARHGAP310.535976303
WFDC10ATSSK20.531758403
WFDC10ARTP50.529053403
WFDC10AEDA2R0.519669303
WFDC10ACHRM40.501197503

For details and further investigation, click here