| Full name: tripartite motif containing 3 | Alias Symbol: HAC1|BERP|RNF97 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 10612 | HGNC ID: HGNC:10064 | Ensembl Gene: ENSG00000110171 | OMIM ID: 605493 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM3 | 10612 | 213885_at | -0.1876 | 0.6084 | |
| GSE20347 | TRIM3 | 10612 | 204911_s_at | -0.0138 | 0.8404 | |
| GSE23400 | TRIM3 | 10612 | 213885_at | -0.2909 | 0.0000 | |
| GSE26886 | TRIM3 | 10612 | 213885_at | -0.1816 | 0.1858 | |
| GSE29001 | TRIM3 | 10612 | 213885_at | -0.3052 | 0.2021 | |
| GSE38129 | TRIM3 | 10612 | 213885_at | -0.3232 | 0.0006 | |
| GSE45670 | TRIM3 | 10612 | 213885_at | -0.1608 | 0.0814 | |
| GSE53622 | TRIM3 | 10612 | 1312 | -0.0506 | 0.5734 | |
| GSE53624 | TRIM3 | 10612 | 1312 | 0.1711 | 0.0110 | |
| GSE63941 | TRIM3 | 10612 | 213885_at | -0.3397 | 0.0518 | |
| GSE77861 | TRIM3 | 10612 | 213885_at | -0.2933 | 0.0036 | |
| GSE97050 | TRIM3 | 10612 | A_33_P3357600 | 0.0329 | 0.9133 | |
| SRP007169 | TRIM3 | 10612 | RNAseq | -0.2829 | 0.6386 | |
| SRP064894 | TRIM3 | 10612 | RNAseq | 0.1614 | 0.2590 | |
| SRP133303 | TRIM3 | 10612 | RNAseq | -0.0835 | 0.6723 | |
| SRP159526 | TRIM3 | 10612 | RNAseq | -0.0821 | 0.7316 | |
| SRP193095 | TRIM3 | 10612 | RNAseq | 0.1693 | 0.4147 | |
| SRP219564 | TRIM3 | 10612 | RNAseq | 0.1537 | 0.6520 | |
| TCGA | TRIM3 | 10612 | RNAseq | -0.3904 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM3 | 10612 | 1 | 11 | 18 | |
| GSE20123 | TRIM3 | 10612 | 1 | 11 | 18 | |
| GSE43470 | TRIM3 | 10612 | 1 | 8 | 34 | |
| GSE46452 | TRIM3 | 10612 | 7 | 8 | 44 | |
| GSE47630 | TRIM3 | 10612 | 2 | 12 | 26 | |
| GSE54993 | TRIM3 | 10612 | 3 | 1 | 66 | |
| GSE54994 | TRIM3 | 10612 | 2 | 12 | 39 | |
| GSE60625 | TRIM3 | 10612 | 0 | 0 | 11 | |
| GSE74703 | TRIM3 | 10612 | 1 | 6 | 29 | |
| GSE74704 | TRIM3 | 10612 | 0 | 8 | 12 | |
| TCGA | TRIM3 | 10612 | 8 | 39 | 49 |
Total number of gains: 26; Total number of losses: 116; Total Number of normals: 346.
Somatic mutations of TRIM3:
Generating mutation plots.
Highly correlated genes for TRIM3:
Showing top 20/460 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM3 | PEX14 | 0.781758 | 3 | 0 | 3 |
| TRIM3 | ADH1A | 0.777462 | 3 | 0 | 3 |
| TRIM3 | CLDN2 | 0.755466 | 3 | 0 | 3 |
| TRIM3 | EVC2 | 0.746084 | 3 | 0 | 3 |
| TRIM3 | ALKBH7 | 0.731766 | 3 | 0 | 3 |
| TRIM3 | CHRNE | 0.730604 | 3 | 0 | 3 |
| TRIM3 | ANKRD44 | 0.726306 | 3 | 0 | 3 |
| TRIM3 | ANK2 | 0.719263 | 3 | 0 | 3 |
| TRIM3 | PARD3 | 0.713193 | 3 | 0 | 3 |
| TRIM3 | OR7E24 | 0.711984 | 4 | 0 | 3 |
| TRIM3 | CADM3 | 0.710977 | 5 | 0 | 5 |
| TRIM3 | C5orf24 | 0.709045 | 3 | 0 | 3 |
| TRIM3 | CAPZB | 0.706704 | 4 | 0 | 3 |
| TRIM3 | STBD1 | 0.705821 | 4 | 0 | 3 |
| TRIM3 | KCNG2 | 0.70375 | 4 | 0 | 4 |
| TRIM3 | PTGIS | 0.702793 | 3 | 0 | 3 |
| TRIM3 | CLK4 | 0.701866 | 3 | 0 | 3 |
| TRIM3 | RASGEF1B | 0.699744 | 3 | 0 | 3 |
| TRIM3 | TOB2 | 0.694866 | 3 | 0 | 3 |
| TRIM3 | SLC25A26 | 0.69009 | 3 | 0 | 3 |
For details and further investigation, click here
