| Full name: plexin A4 | Alias Symbol: KIAA1550|DKFZp434G0625PRO34003|FAYV2820 | ||
| Type: protein-coding gene | Cytoband: 7q32.3 | ||
| Entrez ID: 91584 | HGNC ID: HGNC:9102 | Ensembl Gene: ENSG00000221866 | OMIM ID: 604280 |
| Drug and gene relationship at DGIdb | |||
Expression of PLXNA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLXNA4 | 91584 | 228104_at | -0.7253 | 0.1699 | |
| GSE26886 | PLXNA4 | 91584 | 228104_at | 0.0841 | 0.6262 | |
| GSE45670 | PLXNA4 | 91584 | 228104_at | -0.6575 | 0.0000 | |
| GSE53622 | PLXNA4 | 91584 | 51692 | 0.6393 | 0.0000 | |
| GSE53624 | PLXNA4 | 91584 | 51692 | 0.6267 | 0.0000 | |
| GSE63941 | PLXNA4 | 91584 | 228104_at | -0.5070 | 0.0334 | |
| GSE77861 | PLXNA4 | 91584 | 232317_at | -0.1865 | 0.1994 | |
| GSE97050 | PLXNA4 | 91584 | A_33_P3321034 | 0.3982 | 0.3052 | |
| SRP007169 | PLXNA4 | 91584 | RNAseq | 3.1102 | 0.0109 | |
| SRP064894 | PLXNA4 | 91584 | RNAseq | -1.1849 | 0.0062 | |
| SRP133303 | PLXNA4 | 91584 | RNAseq | -1.3124 | 0.0022 | |
| SRP159526 | PLXNA4 | 91584 | RNAseq | -1.8635 | 0.0000 | |
| SRP193095 | PLXNA4 | 91584 | RNAseq | 0.6247 | 0.1115 | |
| SRP219564 | PLXNA4 | 91584 | RNAseq | -0.9689 | 0.2758 | |
| TCGA | PLXNA4 | 91584 | RNAseq | -0.8184 | 0.0018 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by PLXNA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLXNA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLXNA4 | 91584 | 6 | 1 | 23 | |
| GSE20123 | PLXNA4 | 91584 | 6 | 1 | 23 | |
| GSE43470 | PLXNA4 | 91584 | 2 | 3 | 38 | |
| GSE46452 | PLXNA4 | 91584 | 7 | 2 | 50 | |
| GSE47630 | PLXNA4 | 91584 | 7 | 4 | 29 | |
| GSE54993 | PLXNA4 | 91584 | 3 | 5 | 62 | |
| GSE54994 | PLXNA4 | 91584 | 6 | 7 | 40 | |
| GSE60625 | PLXNA4 | 91584 | 0 | 0 | 11 | |
| GSE74703 | PLXNA4 | 91584 | 2 | 3 | 31 | |
| GSE74704 | PLXNA4 | 91584 | 3 | 1 | 16 | |
| TCGA | PLXNA4 | 91584 | 27 | 23 | 46 |
Total number of gains: 69; Total number of losses: 50; Total Number of normals: 369.
Somatic mutations of PLXNA4:
Generating mutation plots.
Highly correlated genes for PLXNA4:
Showing top 20/158 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLXNA4 | CACNB1 | 0.754154 | 3 | 0 | 3 |
| PLXNA4 | KIAA0408 | 0.73514 | 3 | 0 | 3 |
| PLXNA4 | ZFP36L2 | 0.714601 | 3 | 0 | 3 |
| PLXNA4 | UBXN10-AS1 | 0.703623 | 3 | 0 | 3 |
| PLXNA4 | ZMAT3 | 0.70001 | 3 | 0 | 3 |
| PLXNA4 | PILRA | 0.69777 | 4 | 0 | 4 |
| PLXNA4 | APOB | 0.685117 | 3 | 0 | 3 |
| PLXNA4 | TNFRSF19 | 0.674922 | 4 | 0 | 4 |
| PLXNA4 | CLK3 | 0.67122 | 3 | 0 | 3 |
| PLXNA4 | FAM133B | 0.669334 | 3 | 0 | 3 |
| PLXNA4 | LINC00327 | 0.665636 | 3 | 0 | 3 |
| PLXNA4 | OR2T33 | 0.66445 | 3 | 0 | 3 |
| PLXNA4 | SMARCA2 | 0.664386 | 3 | 0 | 3 |
| PLXNA4 | WFDC10A | 0.661864 | 3 | 0 | 3 |
| PLXNA4 | C17orf64 | 0.657652 | 3 | 0 | 3 |
| PLXNA4 | FILIP1 | 0.653977 | 3 | 0 | 3 |
| PLXNA4 | TMEM106A | 0.653853 | 4 | 0 | 3 |
| PLXNA4 | CSDC2 | 0.652458 | 5 | 0 | 4 |
| PLXNA4 | EVC2 | 0.651304 | 4 | 0 | 3 |
| PLXNA4 | TAS2R43 | 0.650226 | 4 | 0 | 4 |
For details and further investigation, click here
