TMEM178A

 

Full name: transmembrane protein 178A Alias Symbol: MGC33926
Type: protein-coding gene Cytoband: 2p22.1
Entrez ID: 130733 HGNC ID: HGNC:28517 Ensembl Gene: ENSG00000152154 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM178A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM178A 130733 229302_at -1.3373 0.1116
GSE26886 TMEM178A 130733 229302_at -0.1217 0.5995
GSE45670 TMEM178A 130733 229302_at -1.7622 0.0000
GSE53622 TMEM178A 130733 2355 -0.9953 0.0000
GSE53624 TMEM178A 130733 2355 -1.7077 0.0000
GSE63941 TMEM178A 130733 229302_at -4.7824 0.0000
GSE77861 TMEM178A 130733 229302_at 0.2511 0.4559
SRP064894 TMEM178A 130733 RNAseq -1.2132 0.0016
SRP133303 TMEM178A 130733 RNAseq -1.1697 0.0359
SRP159526 TMEM178A 130733 RNAseq -0.5293 0.4550
SRP219564 TMEM178A 130733 RNAseq -0.5644 0.4809

Upregulated datasets: 0; Downregulated datasets: 5.  


 

Survival by TMEM178A expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of TMEM178A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM178A 130733 10 1 19
GSE20123 TMEM178A 130733 9 1 20
GSE43470 TMEM178A 130733 3 0 40
GSE46452 TMEM178A 130733 1 4 54
GSE47630 TMEM178A 130733 7 0 33
GSE54993 TMEM178A 130733 0 5 65
GSE54994 TMEM178A 130733 10 0 43
GSE60625 TMEM178A 130733 0 3 8
GSE74703 TMEM178A 130733 3 0 33
GSE74704 TMEM178A 130733 9 1 10
TCGA TMEM178A 130733 36 2 58

Total number of gains: 88; Total number of losses: 17; Total Number of normals: 383.  


 

Somatic mutations of TMEM178A:

 

Generating mutation plots.

 

Highly correlated genes for TMEM178A:

 

Showing top 20/586 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM178ABMP40.849061303
TMEM178APEG30.839263303
TMEM178AFAT40.816224303
TMEM178ASLIT30.796237303
TMEM178ACYP4V20.792875303
TMEM178AINMT0.790752505
TMEM178ACNN10.790582303
TMEM178APDE5A0.775099505
TMEM178ALINC012790.772273303
TMEM178AZFPM20.770514404
TMEM178AABCB40.769402303
TMEM178AIL17D0.76912303
TMEM178ASYNPO20.763315505
TMEM178AABCA90.760001303
TMEM178ADTNA0.759917303
TMEM178AFAM13C0.758807403
TMEM178ASLC16A40.755689504
TMEM178AMRVI10.754506505
TMEM178AAPOD0.752728404
TMEM178AGFRA10.751709505

For details and further investigation, click here