| Full name: ST6 beta-galactoside alpha-2,6-sialyltransferase 2 | Alias Symbol: KIAA1877|St6gal2|St6GalII | ||
| Type: protein-coding gene | Cytoband: 2q12.3 | ||
| Entrez ID: 84620 | HGNC ID: HGNC:10861 | Ensembl Gene: ENSG00000144057 | OMIM ID: 608472 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GAL2 | 84620 | 228821_at | -1.6726 | 0.1587 | |
| GSE26886 | ST6GAL2 | 84620 | 228821_at | -0.8237 | 0.0684 | |
| GSE45670 | ST6GAL2 | 84620 | 228821_at | -1.9376 | 0.0002 | |
| GSE53622 | ST6GAL2 | 84620 | 105761 | -1.2281 | 0.0000 | |
| GSE53624 | ST6GAL2 | 84620 | 105761 | -1.1604 | 0.0000 | |
| GSE63941 | ST6GAL2 | 84620 | 228821_at | 0.1116 | 0.7241 | |
| GSE77861 | ST6GAL2 | 84620 | 228821_at | -0.4539 | 0.0164 | |
| GSE97050 | ST6GAL2 | 84620 | A_23_P429425 | -1.5959 | 0.1860 | |
| SRP007169 | ST6GAL2 | 84620 | RNAseq | -0.7350 | 0.1506 | |
| SRP064894 | ST6GAL2 | 84620 | RNAseq | -1.1730 | 0.0007 | |
| SRP133303 | ST6GAL2 | 84620 | RNAseq | -0.2221 | 0.4354 | |
| SRP159526 | ST6GAL2 | 84620 | RNAseq | -1.2503 | 0.0841 | |
| SRP193095 | ST6GAL2 | 84620 | RNAseq | -1.4374 | 0.0000 | |
| SRP219564 | ST6GAL2 | 84620 | RNAseq | -0.2361 | 0.5823 | |
| TCGA | ST6GAL2 | 84620 | RNAseq | -0.2014 | 0.5419 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ST6GAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GAL2 | 84620 | 3 | 2 | 25 | |
| GSE20123 | ST6GAL2 | 84620 | 3 | 2 | 25 | |
| GSE43470 | ST6GAL2 | 84620 | 3 | 1 | 39 | |
| GSE46452 | ST6GAL2 | 84620 | 1 | 4 | 54 | |
| GSE47630 | ST6GAL2 | 84620 | 7 | 0 | 33 | |
| GSE54993 | ST6GAL2 | 84620 | 0 | 6 | 64 | |
| GSE54994 | ST6GAL2 | 84620 | 10 | 0 | 43 | |
| GSE60625 | ST6GAL2 | 84620 | 0 | 3 | 8 | |
| GSE74703 | ST6GAL2 | 84620 | 3 | 1 | 32 | |
| GSE74704 | ST6GAL2 | 84620 | 2 | 2 | 16 | |
| TCGA | ST6GAL2 | 84620 | 31 | 6 | 59 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of ST6GAL2:
Generating mutation plots.
Highly correlated genes for ST6GAL2:
Showing top 20/541 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GAL2 | FXYD1 | 0.814794 | 3 | 0 | 3 |
| ST6GAL2 | CCDC136 | 0.807383 | 3 | 0 | 3 |
| ST6GAL2 | DMPK | 0.787538 | 3 | 0 | 3 |
| ST6GAL2 | STARD9 | 0.773746 | 4 | 0 | 4 |
| ST6GAL2 | CNN1 | 0.761304 | 3 | 0 | 3 |
| ST6GAL2 | PEG3 | 0.75628 | 3 | 0 | 3 |
| ST6GAL2 | LMO3 | 0.744954 | 3 | 0 | 3 |
| ST6GAL2 | ZBTB20 | 0.742981 | 3 | 0 | 3 |
| ST6GAL2 | RNASE4 | 0.729047 | 3 | 0 | 3 |
| ST6GAL2 | KIAA0408 | 0.727694 | 4 | 0 | 3 |
| ST6GAL2 | CITED2 | 0.720387 | 4 | 0 | 3 |
| ST6GAL2 | NKX6-1 | 0.720041 | 4 | 0 | 4 |
| ST6GAL2 | PLEKHA5 | 0.714793 | 3 | 0 | 3 |
| ST6GAL2 | FIBIN | 0.714221 | 4 | 0 | 4 |
| ST6GAL2 | OCRL | 0.713237 | 3 | 0 | 3 |
| ST6GAL2 | BNC2 | 0.712065 | 5 | 0 | 5 |
| ST6GAL2 | WWTR1 | 0.71025 | 4 | 0 | 4 |
| ST6GAL2 | CCDC174 | 0.709671 | 3 | 0 | 3 |
| ST6GAL2 | DET1 | 0.706827 | 3 | 0 | 3 |
| ST6GAL2 | SLIT3 | 0.705824 | 3 | 0 | 3 |
For details and further investigation, click here
