| Full name: filamin A interacting protein 1 | Alias Symbol: FILIP|KIAA1275 | ||
| Type: protein-coding gene | Cytoband: 6q14.1 | ||
| Entrez ID: 27145 | HGNC ID: HGNC:21015 | Ensembl Gene: ENSG00000118407 | OMIM ID: 607307 |
| Drug and gene relationship at DGIdb | |||
Expression of FILIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FILIP1 | 27145 | 235183_at | -2.1080 | 0.1154 | |
| GSE26886 | FILIP1 | 27145 | 231945_at | 1.4259 | 0.0098 | |
| GSE45670 | FILIP1 | 27145 | 235183_at | -3.1576 | 0.0000 | |
| GSE53622 | FILIP1 | 27145 | 9366 | -0.8215 | 0.0000 | |
| GSE53624 | FILIP1 | 27145 | 9366 | -0.6195 | 0.0000 | |
| GSE63941 | FILIP1 | 27145 | 231945_at | -0.2312 | 0.7839 | |
| GSE77861 | FILIP1 | 27145 | 231945_at | 0.3011 | 0.0980 | |
| GSE97050 | FILIP1 | 27145 | A_33_P3276435 | -0.5353 | 0.2727 | |
| SRP007169 | FILIP1 | 27145 | RNAseq | 1.9943 | 0.0235 | |
| SRP008496 | FILIP1 | 27145 | RNAseq | 3.1481 | 0.0000 | |
| SRP064894 | FILIP1 | 27145 | RNAseq | -0.1948 | 0.6439 | |
| SRP133303 | FILIP1 | 27145 | RNAseq | -0.3067 | 0.4441 | |
| SRP159526 | FILIP1 | 27145 | RNAseq | -0.2091 | 0.7326 | |
| SRP193095 | FILIP1 | 27145 | RNAseq | 0.6113 | 0.0008 | |
| SRP219564 | FILIP1 | 27145 | RNAseq | -0.6278 | 0.4228 | |
| TCGA | FILIP1 | 27145 | RNAseq | -0.6451 | 0.0004 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by FILIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FILIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FILIP1 | 27145 | 1 | 3 | 26 | |
| GSE20123 | FILIP1 | 27145 | 1 | 2 | 27 | |
| GSE43470 | FILIP1 | 27145 | 3 | 0 | 40 | |
| GSE46452 | FILIP1 | 27145 | 2 | 11 | 46 | |
| GSE47630 | FILIP1 | 27145 | 8 | 4 | 28 | |
| GSE54993 | FILIP1 | 27145 | 3 | 2 | 65 | |
| GSE54994 | FILIP1 | 27145 | 8 | 6 | 39 | |
| GSE60625 | FILIP1 | 27145 | 0 | 1 | 10 | |
| GSE74703 | FILIP1 | 27145 | 3 | 0 | 33 | |
| GSE74704 | FILIP1 | 27145 | 0 | 1 | 19 | |
| TCGA | FILIP1 | 27145 | 9 | 21 | 66 |
Total number of gains: 38; Total number of losses: 51; Total Number of normals: 399.
Somatic mutations of FILIP1:
Generating mutation plots.
Highly correlated genes for FILIP1:
Showing top 20/864 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FILIP1 | CNN1 | 0.936964 | 3 | 0 | 3 |
| FILIP1 | TMOD1 | 0.868066 | 3 | 0 | 3 |
| FILIP1 | CACNA1C | 0.847408 | 4 | 0 | 4 |
| FILIP1 | BHMT2 | 0.842188 | 5 | 0 | 5 |
| FILIP1 | CHRDL1 | 0.841157 | 4 | 0 | 4 |
| FILIP1 | MRVI1 | 0.837423 | 5 | 0 | 5 |
| FILIP1 | MYOCD | 0.835013 | 5 | 0 | 5 |
| FILIP1 | FXYD1 | 0.8275 | 3 | 0 | 3 |
| FILIP1 | RASSF3 | 0.825028 | 4 | 0 | 4 |
| FILIP1 | NEXN | 0.8245 | 5 | 0 | 5 |
| FILIP1 | ANK2 | 0.820934 | 5 | 0 | 5 |
| FILIP1 | CASQ2 | 0.810502 | 5 | 0 | 5 |
| FILIP1 | PEG3 | 0.810367 | 3 | 0 | 3 |
| FILIP1 | HSPB7 | 0.810122 | 5 | 0 | 5 |
| FILIP1 | DIXDC1 | 0.807882 | 5 | 0 | 5 |
| FILIP1 | LZTR1 | 0.80527 | 3 | 0 | 3 |
| FILIP1 | ROCK1 | 0.805262 | 4 | 0 | 4 |
| FILIP1 | JPH2 | 0.80509 | 3 | 0 | 3 |
| FILIP1 | NEGR1 | 0.804556 | 5 | 0 | 5 |
| FILIP1 | RNASE4 | 0.802888 | 4 | 0 | 4 |
For details and further investigation, click here
