| Full name: SATB homeobox 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p24.3 | ||
| Entrez ID: 6304 | HGNC ID: HGNC:10541 | Ensembl Gene: ENSG00000182568 | OMIM ID: 602075 |
| Drug and gene relationship at DGIdb | |||
Expression of SATB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SATB1 | 6304 | 203408_s_at | -0.9429 | 0.0797 | |
| GSE20347 | SATB1 | 6304 | 203408_s_at | -0.9490 | 0.0006 | |
| GSE23400 | SATB1 | 6304 | 203408_s_at | -0.4598 | 0.0000 | |
| GSE26886 | SATB1 | 6304 | 203408_s_at | -0.5657 | 0.0520 | |
| GSE29001 | SATB1 | 6304 | 203408_s_at | -0.7460 | 0.0322 | |
| GSE38129 | SATB1 | 6304 | 203408_s_at | -1.0894 | 0.0000 | |
| GSE45670 | SATB1 | 6304 | 203408_s_at | -0.7782 | 0.0142 | |
| GSE53622 | SATB1 | 6304 | 123076 | -0.7808 | 0.0000 | |
| GSE53624 | SATB1 | 6304 | 123076 | -0.7331 | 0.0000 | |
| GSE63941 | SATB1 | 6304 | 203408_s_at | -0.9595 | 0.5115 | |
| GSE77861 | SATB1 | 6304 | 203408_s_at | -0.3537 | 0.3724 | |
| GSE97050 | SATB1 | 6304 | A_23_P259741 | -0.7451 | 0.0631 | |
| SRP007169 | SATB1 | 6304 | RNAseq | -0.7985 | 0.1213 | |
| SRP008496 | SATB1 | 6304 | RNAseq | -0.4620 | 0.1703 | |
| SRP064894 | SATB1 | 6304 | RNAseq | -0.4686 | 0.1126 | |
| SRP133303 | SATB1 | 6304 | RNAseq | -0.4125 | 0.0742 | |
| SRP159526 | SATB1 | 6304 | RNAseq | -0.9392 | 0.0027 | |
| SRP193095 | SATB1 | 6304 | RNAseq | -0.2527 | 0.1223 | |
| SRP219564 | SATB1 | 6304 | RNAseq | -1.3961 | 0.0002 | |
| TCGA | SATB1 | 6304 | RNAseq | -0.5454 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SATB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SATB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SATB1 | 6304 | 1 | 19 | 10 | |
| GSE20123 | SATB1 | 6304 | 1 | 19 | 10 | |
| GSE43470 | SATB1 | 6304 | 0 | 20 | 23 | |
| GSE46452 | SATB1 | 6304 | 2 | 17 | 40 | |
| GSE47630 | SATB1 | 6304 | 1 | 24 | 15 | |
| GSE54993 | SATB1 | 6304 | 6 | 1 | 63 | |
| GSE54994 | SATB1 | 6304 | 1 | 32 | 20 | |
| GSE60625 | SATB1 | 6304 | 5 | 0 | 6 | |
| GSE74703 | SATB1 | 6304 | 0 | 17 | 19 | |
| GSE74704 | SATB1 | 6304 | 0 | 13 | 7 | |
| TCGA | SATB1 | 6304 | 1 | 68 | 27 |
Total number of gains: 18; Total number of losses: 230; Total Number of normals: 240.
Somatic mutations of SATB1:
Generating mutation plots.
Highly correlated genes for SATB1:
Showing top 20/1150 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SATB1 | MSRB3 | 0.838257 | 3 | 0 | 3 |
| SATB1 | MIER1 | 0.785241 | 3 | 0 | 3 |
| SATB1 | CCDC80 | 0.779796 | 3 | 0 | 3 |
| SATB1 | CYP4V2 | 0.769357 | 3 | 0 | 3 |
| SATB1 | NKAPL | 0.76822 | 3 | 0 | 3 |
| SATB1 | DCHS1 | 0.739228 | 3 | 0 | 3 |
| SATB1 | EIF4E3 | 0.738648 | 6 | 0 | 6 |
| SATB1 | ZBTB20 | 0.728045 | 6 | 0 | 6 |
| SATB1 | YME1L1 | 0.726625 | 3 | 0 | 3 |
| SATB1 | CRBN | 0.725572 | 8 | 0 | 8 |
| SATB1 | C9orf72 | 0.724923 | 3 | 0 | 3 |
| SATB1 | BVES | 0.722459 | 3 | 0 | 3 |
| SATB1 | MFAP4 | 0.718804 | 6 | 0 | 5 |
| SATB1 | PREX2 | 0.713312 | 4 | 0 | 3 |
| SATB1 | UBXN10 | 0.708133 | 3 | 0 | 3 |
| SATB1 | GNG2 | 0.705995 | 3 | 0 | 3 |
| SATB1 | TCEAL4 | 0.705528 | 3 | 0 | 3 |
| SATB1 | CPXM2 | 0.705457 | 5 | 0 | 4 |
| SATB1 | CREBRF | 0.703768 | 3 | 0 | 3 |
| SATB1 | MEIS1 | 0.703284 | 10 | 0 | 10 |
For details and further investigation, click here
