| Full name: zinc finger and BTB domain containing 21 | Alias Symbol: KIAA1227 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 49854 | HGNC ID: HGNC:13083 | Ensembl Gene: ENSG00000173276 | OMIM ID: 616485 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB21 | 49854 | 233952_s_at | -0.0741 | 0.9295 | |
| GSE26886 | ZBTB21 | 49854 | 225539_at | -0.3392 | 0.2652 | |
| GSE45670 | ZBTB21 | 49854 | 225539_at | -0.0792 | 0.6787 | |
| GSE53622 | ZBTB21 | 49854 | 27831 | -0.2109 | 0.0093 | |
| GSE53624 | ZBTB21 | 49854 | 27831 | 0.0378 | 0.6799 | |
| GSE63941 | ZBTB21 | 49854 | 233952_s_at | -0.4383 | 0.4877 | |
| GSE77861 | ZBTB21 | 49854 | 233952_s_at | 0.3886 | 0.4343 | |
| SRP007169 | ZBTB21 | 49854 | RNAseq | 0.7305 | 0.0494 | |
| SRP008496 | ZBTB21 | 49854 | RNAseq | 0.6014 | 0.0171 | |
| SRP064894 | ZBTB21 | 49854 | RNAseq | -0.0676 | 0.8008 | |
| SRP133303 | ZBTB21 | 49854 | RNAseq | 0.0636 | 0.7393 | |
| SRP159526 | ZBTB21 | 49854 | RNAseq | -0.1687 | 0.6736 | |
| SRP193095 | ZBTB21 | 49854 | RNAseq | 0.1688 | 0.1492 | |
| SRP219564 | ZBTB21 | 49854 | RNAseq | -0.1621 | 0.6211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB21 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ZBTB21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB21 | 49854 | 2 | 8 | 20 | |
| GSE20123 | ZBTB21 | 49854 | 2 | 8 | 20 | |
| GSE43470 | ZBTB21 | 49854 | 0 | 13 | 30 | |
| GSE46452 | ZBTB21 | 49854 | 1 | 21 | 37 | |
| GSE47630 | ZBTB21 | 49854 | 6 | 17 | 17 | |
| GSE54993 | ZBTB21 | 49854 | 8 | 1 | 61 | |
| GSE54994 | ZBTB21 | 49854 | 3 | 8 | 42 | |
| GSE60625 | ZBTB21 | 49854 | 0 | 0 | 11 | |
| GSE74703 | ZBTB21 | 49854 | 0 | 10 | 26 | |
| GSE74704 | ZBTB21 | 49854 | 1 | 4 | 15 | |
| TCGA | ZBTB21 | 49854 | 7 | 41 | 48 |
Total number of gains: 30; Total number of losses: 131; Total Number of normals: 327.
Somatic mutations of ZBTB21:
Generating mutation plots.
Highly correlated genes for ZBTB21:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB21 | KIAA0753 | 0.710937 | 3 | 0 | 3 |
| ZBTB21 | RAB11FIP2 | 0.66401 | 4 | 0 | 4 |
| ZBTB21 | KMT2A | 0.612958 | 4 | 0 | 3 |
| ZBTB21 | VAMP4 | 0.592047 | 4 | 0 | 4 |
| ZBTB21 | TAPT1 | 0.558297 | 3 | 0 | 3 |
| ZBTB21 | DCP1A | 0.552022 | 5 | 0 | 3 |
| ZBTB21 | DCUN1D4 | 0.551501 | 4 | 0 | 3 |
| ZBTB21 | FAM76B | 0.546795 | 3 | 0 | 3 |
| ZBTB21 | ARRDC4 | 0.542202 | 4 | 0 | 3 |
| ZBTB21 | RAB33B | 0.535695 | 5 | 0 | 3 |
| ZBTB21 | MTMR9 | 0.535237 | 4 | 0 | 3 |
| ZBTB21 | FBXO30 | 0.534075 | 4 | 0 | 3 |
| ZBTB21 | SLC19A2 | 0.532307 | 5 | 0 | 3 |
| ZBTB21 | TMED5 | 0.5293 | 4 | 0 | 3 |
| ZBTB21 | ZBTB2 | 0.529044 | 3 | 0 | 3 |
| ZBTB21 | ARIH2 | 0.510237 | 5 | 0 | 3 |
For details and further investigation, click here
