| Full name: ariadne RBR E3 ubiquitin protein ligase 2 | Alias Symbol: TRIAD1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 10425 | HGNC ID: HGNC:690 | Ensembl Gene: ENSG00000177479 | OMIM ID: 605615 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARIH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARIH2 | 10425 | 227932_at | -0.2891 | 0.5327 | |
| GSE20347 | ARIH2 | 10425 | 201229_s_at | -0.3506 | 0.0193 | |
| GSE23400 | ARIH2 | 10425 | 201230_s_at | -0.1172 | 0.0293 | |
| GSE26886 | ARIH2 | 10425 | 201230_s_at | -0.2913 | 0.1634 | |
| GSE29001 | ARIH2 | 10425 | 201230_s_at | -0.3082 | 0.0778 | |
| GSE38129 | ARIH2 | 10425 | 201229_s_at | -0.3591 | 0.0005 | |
| GSE45670 | ARIH2 | 10425 | 227932_at | -0.2500 | 0.1823 | |
| GSE53622 | ARIH2 | 10425 | 38255 | -0.2402 | 0.0000 | |
| GSE53624 | ARIH2 | 10425 | 38255 | -0.1303 | 0.0032 | |
| GSE63941 | ARIH2 | 10425 | 201229_s_at | 0.5170 | 0.1210 | |
| GSE77861 | ARIH2 | 10425 | 201230_s_at | 0.0851 | 0.5893 | |
| GSE97050 | ARIH2 | 10425 | A_23_P61881 | -0.0519 | 0.8533 | |
| SRP007169 | ARIH2 | 10425 | RNAseq | -0.0842 | 0.8258 | |
| SRP008496 | ARIH2 | 10425 | RNAseq | -0.1948 | 0.3804 | |
| SRP064894 | ARIH2 | 10425 | RNAseq | -0.2697 | 0.0115 | |
| SRP133303 | ARIH2 | 10425 | RNAseq | -0.3005 | 0.0390 | |
| SRP159526 | ARIH2 | 10425 | RNAseq | -0.3117 | 0.1098 | |
| SRP193095 | ARIH2 | 10425 | RNAseq | -0.2994 | 0.0004 | |
| SRP219564 | ARIH2 | 10425 | RNAseq | -0.3075 | 0.4121 | |
| TCGA | ARIH2 | 10425 | RNAseq | -0.2383 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARIH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARIH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARIH2 | 10425 | 0 | 18 | 12 | |
| GSE20123 | ARIH2 | 10425 | 0 | 19 | 11 | |
| GSE43470 | ARIH2 | 10425 | 0 | 19 | 24 | |
| GSE46452 | ARIH2 | 10425 | 2 | 16 | 41 | |
| GSE47630 | ARIH2 | 10425 | 1 | 24 | 15 | |
| GSE54993 | ARIH2 | 10425 | 6 | 2 | 62 | |
| GSE54994 | ARIH2 | 10425 | 0 | 37 | 16 | |
| GSE60625 | ARIH2 | 10425 | 5 | 0 | 6 | |
| GSE74703 | ARIH2 | 10425 | 0 | 15 | 21 | |
| GSE74704 | ARIH2 | 10425 | 0 | 12 | 8 | |
| TCGA | ARIH2 | 10425 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 240; Total Number of normals: 234.
Somatic mutations of ARIH2:
Generating mutation plots.
Highly correlated genes for ARIH2:
Showing top 20/278 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARIH2 | SRSF4 | 0.785335 | 3 | 0 | 3 |
| ARIH2 | RSRC2 | 0.779078 | 3 | 0 | 3 |
| ARIH2 | CREBZF | 0.732123 | 3 | 0 | 3 |
| ARIH2 | ZYG11B | 0.724825 | 3 | 0 | 3 |
| ARIH2 | SOS2 | 0.717196 | 4 | 0 | 3 |
| ARIH2 | KIAA1143 | 0.717119 | 4 | 0 | 4 |
| ARIH2 | HECTD3 | 0.700153 | 3 | 0 | 3 |
| ARIH2 | WWP1 | 0.696281 | 3 | 0 | 3 |
| ARIH2 | DIS3L | 0.695909 | 3 | 0 | 3 |
| ARIH2 | CUL1 | 0.694947 | 3 | 0 | 3 |
| ARIH2 | PPP1R15A | 0.691508 | 3 | 0 | 3 |
| ARIH2 | POLR3GL | 0.690403 | 3 | 0 | 3 |
| ARIH2 | NDUFA8 | 0.689046 | 3 | 0 | 3 |
| ARIH2 | PDCD7 | 0.686048 | 3 | 0 | 3 |
| ARIH2 | CCDC121 | 0.683296 | 3 | 0 | 3 |
| ARIH2 | EPC1 | 0.675284 | 3 | 0 | 3 |
| ARIH2 | TM9SF3 | 0.672271 | 3 | 0 | 3 |
| ARIH2 | WDR35 | 0.671803 | 3 | 0 | 3 |
| ARIH2 | ANGPTL7 | 0.670939 | 4 | 0 | 3 |
| ARIH2 | TMEM126A | 0.66347 | 3 | 0 | 3 |
For details and further investigation, click here
