| Full name: zinc finger and BTB domain containing 2 | Alias Symbol: KIAA1483|ZNF437|bA351K16.2 | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 57621 | HGNC ID: HGNC:20868 | Ensembl Gene: ENSG00000181472 | OMIM ID: 616595 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZBTB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB2 | 57621 | 226284_at | 0.4284 | 0.2892 | |
| GSE26886 | ZBTB2 | 57621 | 226284_at | 0.5127 | 0.0050 | |
| GSE45670 | ZBTB2 | 57621 | 226284_at | 0.0428 | 0.8431 | |
| GSE53622 | ZBTB2 | 57621 | 66715 | 0.4315 | 0.0000 | |
| GSE53624 | ZBTB2 | 57621 | 66715 | 0.6790 | 0.0000 | |
| GSE63941 | ZBTB2 | 57621 | 226284_at | -1.1362 | 0.0084 | |
| GSE77861 | ZBTB2 | 57621 | 226284_at | 0.5537 | 0.0130 | |
| GSE97050 | ZBTB2 | 57621 | A_23_P82108 | 0.2578 | 0.4085 | |
| SRP007169 | ZBTB2 | 57621 | RNAseq | 1.3721 | 0.0024 | |
| SRP008496 | ZBTB2 | 57621 | RNAseq | 1.4644 | 0.0001 | |
| SRP064894 | ZBTB2 | 57621 | RNAseq | 0.3662 | 0.0407 | |
| SRP133303 | ZBTB2 | 57621 | RNAseq | 0.4602 | 0.0026 | |
| SRP159526 | ZBTB2 | 57621 | RNAseq | 0.2623 | 0.1987 | |
| SRP193095 | ZBTB2 | 57621 | RNAseq | 0.2954 | 0.0018 | |
| SRP219564 | ZBTB2 | 57621 | RNAseq | 0.4039 | 0.1605 | |
| TCGA | ZBTB2 | 57621 | RNAseq | 0.1379 | 0.0127 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ZBTB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB2 | 57621 | 1 | 4 | 25 | |
| GSE20123 | ZBTB2 | 57621 | 1 | 3 | 26 | |
| GSE43470 | ZBTB2 | 57621 | 4 | 0 | 39 | |
| GSE46452 | ZBTB2 | 57621 | 3 | 10 | 46 | |
| GSE47630 | ZBTB2 | 57621 | 9 | 4 | 27 | |
| GSE54993 | ZBTB2 | 57621 | 3 | 2 | 65 | |
| GSE54994 | ZBTB2 | 57621 | 8 | 8 | 37 | |
| GSE60625 | ZBTB2 | 57621 | 0 | 1 | 10 | |
| GSE74703 | ZBTB2 | 57621 | 4 | 0 | 32 | |
| GSE74704 | ZBTB2 | 57621 | 0 | 1 | 19 | |
| TCGA | ZBTB2 | 57621 | 12 | 20 | 64 |
Total number of gains: 45; Total number of losses: 53; Total Number of normals: 390.
Somatic mutations of ZBTB2:
Generating mutation plots.
Highly correlated genes for ZBTB2:
Showing top 20/1183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB2 | SRSF6 | 0.881033 | 3 | 0 | 3 |
| ZBTB2 | CCNT1 | 0.851427 | 3 | 0 | 3 |
| ZBTB2 | NACC1 | 0.817097 | 3 | 0 | 3 |
| ZBTB2 | SCAF8 | 0.799296 | 3 | 0 | 3 |
| ZBTB2 | ZBED6 | 0.783789 | 3 | 0 | 3 |
| ZBTB2 | GOLGA3 | 0.782418 | 3 | 0 | 3 |
| ZBTB2 | ZNF578 | 0.780409 | 3 | 0 | 3 |
| ZBTB2 | ZNF124 | 0.763328 | 3 | 0 | 3 |
| ZBTB2 | SFSWAP | 0.758175 | 3 | 0 | 3 |
| ZBTB2 | RNF138 | 0.754907 | 3 | 0 | 3 |
| ZBTB2 | FCGR3A | 0.751869 | 3 | 0 | 3 |
| ZBTB2 | UBAP2L | 0.7467 | 3 | 0 | 3 |
| ZBTB2 | GEMIN5 | 0.741287 | 3 | 0 | 3 |
| ZBTB2 | KDSR | 0.740828 | 3 | 0 | 3 |
| ZBTB2 | ZNF71 | 0.738582 | 3 | 0 | 3 |
| ZBTB2 | POMZP3 | 0.737276 | 3 | 0 | 3 |
| ZBTB2 | SRSF10 | 0.735667 | 4 | 0 | 4 |
| ZBTB2 | ZNF202 | 0.735464 | 4 | 0 | 3 |
| ZBTB2 | PAIP1 | 0.734819 | 4 | 0 | 4 |
| ZBTB2 | ZSCAN29 | 0.733384 | 3 | 0 | 3 |
For details and further investigation, click here
