| Full name: decapping mRNA 1A | Alias Symbol: HSA275986|SMIF|SMAD4IP1 | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 55802 | HGNC ID: HGNC:18714 | Ensembl Gene: ENSG00000272886 | OMIM ID: 607010 |
| Drug and gene relationship at DGIdb | |||
Expression of DCP1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCP1A | 55802 | 218508_at | 0.0789 | 0.7908 | |
| GSE20347 | DCP1A | 55802 | 218508_at | -0.3469 | 0.0041 | |
| GSE23400 | DCP1A | 55802 | 218508_at | -0.2006 | 0.0000 | |
| GSE26886 | DCP1A | 55802 | 225443_at | 0.1643 | 0.4338 | |
| GSE29001 | DCP1A | 55802 | 218508_at | -0.4074 | 0.0241 | |
| GSE38129 | DCP1A | 55802 | 218508_at | -0.5496 | 0.0000 | |
| GSE45670 | DCP1A | 55802 | 225443_at | -0.2592 | 0.0096 | |
| GSE53622 | DCP1A | 55802 | 20211 | -0.7380 | 0.0000 | |
| GSE53624 | DCP1A | 55802 | 15980 | -0.3649 | 0.0000 | |
| GSE63941 | DCP1A | 55802 | 225443_at | -0.1142 | 0.7608 | |
| GSE77861 | DCP1A | 55802 | 218508_at | -0.1891 | 0.2144 | |
| GSE97050 | DCP1A | 55802 | A_24_P576174 | -0.5435 | 0.2066 | |
| SRP007169 | DCP1A | 55802 | RNAseq | -0.2281 | 0.5351 | |
| SRP008496 | DCP1A | 55802 | RNAseq | -0.0868 | 0.7065 | |
| SRP064894 | DCP1A | 55802 | RNAseq | -0.3069 | 0.0130 | |
| SRP133303 | DCP1A | 55802 | RNAseq | -0.3521 | 0.0002 | |
| SRP159526 | DCP1A | 55802 | RNAseq | -0.4845 | 0.0048 | |
| SRP193095 | DCP1A | 55802 | RNAseq | -0.3398 | 0.0000 | |
| SRP219564 | DCP1A | 55802 | RNAseq | -0.6953 | 0.0034 | |
| TCGA | DCP1A | 55802 | RNAseq | -0.1570 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCP1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCP1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCP1A | 55802 | 0 | 19 | 11 | |
| GSE20123 | DCP1A | 55802 | 0 | 20 | 10 | |
| GSE43470 | DCP1A | 55802 | 0 | 18 | 25 | |
| GSE46452 | DCP1A | 55802 | 2 | 17 | 40 | |
| GSE47630 | DCP1A | 55802 | 1 | 24 | 15 | |
| GSE54993 | DCP1A | 55802 | 6 | 2 | 62 | |
| GSE54994 | DCP1A | 55802 | 0 | 32 | 21 | |
| GSE60625 | DCP1A | 55802 | 5 | 0 | 6 | |
| GSE74703 | DCP1A | 55802 | 0 | 14 | 22 | |
| GSE74704 | DCP1A | 55802 | 0 | 13 | 7 | |
| TCGA | DCP1A | 55802 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of DCP1A:
Generating mutation plots.
Highly correlated genes for DCP1A:
Showing top 20/538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCP1A | PPM1B | 0.791188 | 3 | 0 | 3 |
| DCP1A | GGA3 | 0.784566 | 3 | 0 | 3 |
| DCP1A | PDK2 | 0.740594 | 3 | 0 | 3 |
| DCP1A | PRMT2 | 0.729606 | 4 | 0 | 4 |
| DCP1A | NDUFS1 | 0.728509 | 3 | 0 | 3 |
| DCP1A | UBE2R2 | 0.712865 | 3 | 0 | 3 |
| DCP1A | ANAPC16 | 0.708115 | 3 | 0 | 3 |
| DCP1A | HDAC11 | 0.705733 | 4 | 0 | 3 |
| DCP1A | IP6K1 | 0.7038 | 4 | 0 | 3 |
| DCP1A | ZBTB22 | 0.70028 | 3 | 0 | 3 |
| DCP1A | ZNF662 | 0.698443 | 3 | 0 | 3 |
| DCP1A | RWDD2B | 0.694912 | 4 | 0 | 4 |
| DCP1A | C17orf80 | 0.682349 | 3 | 0 | 3 |
| DCP1A | ST6GALNAC6 | 0.678188 | 4 | 0 | 4 |
| DCP1A | SETD2 | 0.676088 | 9 | 0 | 9 |
| DCP1A | SAP18 | 0.672167 | 4 | 0 | 3 |
| DCP1A | KPNA3 | 0.671058 | 3 | 0 | 3 |
| DCP1A | BTRC | 0.670612 | 3 | 0 | 3 |
| DCP1A | TSC22D3 | 0.667852 | 5 | 0 | 4 |
| DCP1A | UTP14C | 0.667779 | 3 | 0 | 3 |
For details and further investigation, click here
