| Full name: transmembrane p24 trafficking protein 5 | Alias Symbol: CGI-100|p24g2|p24gamma2 | ||
| Type: protein-coding gene | Cytoband: 1p22.1 | ||
| Entrez ID: 50999 | HGNC ID: HGNC:24251 | Ensembl Gene: ENSG00000117500 | OMIM ID: 616876 |
| Drug and gene relationship at DGIdb | |||
Expression of TMED5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMED5 | 50999 | 202194_at | -0.1384 | 0.7231 | |
| GSE20347 | TMED5 | 50999 | 202194_at | -0.1197 | 0.5954 | |
| GSE23400 | TMED5 | 50999 | 202194_at | 0.2594 | 0.0039 | |
| GSE26886 | TMED5 | 50999 | 202194_at | -0.3305 | 0.1714 | |
| GSE29001 | TMED5 | 50999 | 202194_at | 0.2773 | 0.5834 | |
| GSE38129 | TMED5 | 50999 | 202194_at | -0.0282 | 0.8847 | |
| GSE45670 | TMED5 | 50999 | 202194_at | 0.0458 | 0.8527 | |
| GSE53622 | TMED5 | 50999 | 22490 | 0.2704 | 0.0002 | |
| GSE53624 | TMED5 | 50999 | 31155 | 0.0934 | 0.1584 | |
| GSE63941 | TMED5 | 50999 | 202194_at | -0.8109 | 0.2202 | |
| GSE77861 | TMED5 | 50999 | 202194_at | -0.1648 | 0.5708 | |
| GSE97050 | TMED5 | 50999 | A_23_P86002 | 0.5765 | 0.2569 | |
| SRP007169 | TMED5 | 50999 | RNAseq | 0.0196 | 0.9519 | |
| SRP008496 | TMED5 | 50999 | RNAseq | 0.0227 | 0.8964 | |
| SRP064894 | TMED5 | 50999 | RNAseq | 0.5392 | 0.0070 | |
| SRP133303 | TMED5 | 50999 | RNAseq | 0.6514 | 0.0001 | |
| SRP159526 | TMED5 | 50999 | RNAseq | -0.2845 | 0.4183 | |
| SRP193095 | TMED5 | 50999 | RNAseq | 0.3154 | 0.0923 | |
| SRP219564 | TMED5 | 50999 | RNAseq | 0.1789 | 0.6955 | |
| TCGA | TMED5 | 50999 | RNAseq | -0.1052 | 0.0257 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMED5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMED5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMED5 | 50999 | 0 | 8 | 22 | |
| GSE20123 | TMED5 | 50999 | 0 | 8 | 22 | |
| GSE43470 | TMED5 | 50999 | 2 | 6 | 35 | |
| GSE46452 | TMED5 | 50999 | 1 | 1 | 57 | |
| GSE47630 | TMED5 | 50999 | 8 | 5 | 27 | |
| GSE54993 | TMED5 | 50999 | 0 | 1 | 69 | |
| GSE54994 | TMED5 | 50999 | 6 | 3 | 44 | |
| GSE60625 | TMED5 | 50999 | 0 | 0 | 11 | |
| GSE74703 | TMED5 | 50999 | 1 | 5 | 30 | |
| GSE74704 | TMED5 | 50999 | 0 | 5 | 15 | |
| TCGA | TMED5 | 50999 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of TMED5:
Generating mutation plots.
Highly correlated genes for TMED5:
Showing top 20/448 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMED5 | RPP38 | 0.797084 | 3 | 0 | 3 |
| TMED5 | MAGOHB | 0.708657 | 3 | 0 | 3 |
| TMED5 | FAM122C | 0.691869 | 3 | 0 | 3 |
| TMED5 | GPHN | 0.68562 | 3 | 0 | 3 |
| TMED5 | STAMBP | 0.684481 | 3 | 0 | 3 |
| TMED5 | VPS35 | 0.684096 | 3 | 0 | 3 |
| TMED5 | C1QBP | 0.682894 | 4 | 0 | 3 |
| TMED5 | RWDD2B | 0.682748 | 3 | 0 | 3 |
| TMED5 | MED4 | 0.682391 | 3 | 0 | 3 |
| TMED5 | MAS1L | 0.681509 | 3 | 0 | 3 |
| TMED5 | SLC15A4 | 0.676771 | 4 | 0 | 4 |
| TMED5 | SLC30A7 | 0.672263 | 5 | 0 | 4 |
| TMED5 | CDC123 | 0.672116 | 4 | 0 | 4 |
| TMED5 | CCDC91 | 0.671381 | 5 | 0 | 5 |
| TMED5 | HLA-DRA | 0.670524 | 3 | 0 | 3 |
| TMED5 | BZW2 | 0.670442 | 3 | 0 | 3 |
| TMED5 | SIKE1 | 0.668416 | 4 | 0 | 3 |
| TMED5 | KRT71 | 0.667345 | 3 | 0 | 3 |
| TMED5 | RPE | 0.666837 | 4 | 0 | 3 |
| TMED5 | TMEM106B | 0.666758 | 3 | 0 | 3 |
For details and further investigation, click here
