| Full name: F-box protein 30 | Alias Symbol: MGC21674|Fbx30 | ||
| Type: protein-coding gene | Cytoband: 6q24.3 | ||
| Entrez ID: 84085 | HGNC ID: HGNC:15600 | Ensembl Gene: ENSG00000118496 | OMIM ID: 609101 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO30 | 84085 | 226541_at | -0.5717 | 0.5389 | |
| GSE26886 | FBXO30 | 84085 | 226541_at | -0.1952 | 0.4839 | |
| GSE45670 | FBXO30 | 84085 | 226541_at | -0.6176 | 0.0033 | |
| GSE53622 | FBXO30 | 84085 | 45134 | -0.6070 | 0.0000 | |
| GSE53624 | FBXO30 | 84085 | 45134 | -0.3162 | 0.0001 | |
| GSE63941 | FBXO30 | 84085 | 226541_at | -1.1919 | 0.0103 | |
| GSE77861 | FBXO30 | 84085 | 226541_at | 0.5703 | 0.0529 | |
| GSE97050 | FBXO30 | 84085 | A_23_P256231 | -0.9539 | 0.1351 | |
| SRP007169 | FBXO30 | 84085 | RNAseq | 0.6005 | 0.1742 | |
| SRP008496 | FBXO30 | 84085 | RNAseq | 1.2095 | 0.0004 | |
| SRP064894 | FBXO30 | 84085 | RNAseq | -0.3932 | 0.1501 | |
| SRP133303 | FBXO30 | 84085 | RNAseq | 0.0055 | 0.9855 | |
| SRP159526 | FBXO30 | 84085 | RNAseq | -0.1230 | 0.6609 | |
| SRP193095 | FBXO30 | 84085 | RNAseq | 0.0494 | 0.6991 | |
| SRP219564 | FBXO30 | 84085 | RNAseq | -0.7219 | 0.1665 | |
| TCGA | FBXO30 | 84085 | RNAseq | -0.1024 | 0.0915 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by FBXO30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO30 | 84085 | 2 | 4 | 24 | |
| GSE20123 | FBXO30 | 84085 | 2 | 3 | 25 | |
| GSE43470 | FBXO30 | 84085 | 5 | 0 | 38 | |
| GSE46452 | FBXO30 | 84085 | 3 | 11 | 45 | |
| GSE47630 | FBXO30 | 84085 | 9 | 4 | 27 | |
| GSE54993 | FBXO30 | 84085 | 3 | 2 | 65 | |
| GSE54994 | FBXO30 | 84085 | 8 | 8 | 37 | |
| GSE60625 | FBXO30 | 84085 | 0 | 1 | 10 | |
| GSE74703 | FBXO30 | 84085 | 4 | 0 | 32 | |
| GSE74704 | FBXO30 | 84085 | 0 | 1 | 19 | |
| TCGA | FBXO30 | 84085 | 12 | 19 | 65 |
Total number of gains: 48; Total number of losses: 53; Total Number of normals: 387.
Somatic mutations of FBXO30:
Generating mutation plots.
Highly correlated genes for FBXO30:
Showing top 20/688 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO30 | FGF12 | 0.847081 | 3 | 0 | 3 |
| FBXO30 | FNDC5 | 0.841658 | 3 | 0 | 3 |
| FBXO30 | MYL6 | 0.824874 | 3 | 0 | 3 |
| FBXO30 | ZER1 | 0.802346 | 3 | 0 | 3 |
| FBXO30 | DTNA | 0.780297 | 4 | 0 | 4 |
| FBXO30 | LUC7L | 0.779663 | 3 | 0 | 3 |
| FBXO30 | TTLL7 | 0.75922 | 4 | 0 | 4 |
| FBXO30 | CD34 | 0.755368 | 3 | 0 | 3 |
| FBXO30 | WWTR1 | 0.749708 | 4 | 0 | 4 |
| FBXO30 | LMO3 | 0.749155 | 4 | 0 | 4 |
| FBXO30 | RABGAP1 | 0.747564 | 3 | 0 | 3 |
| FBXO30 | FASTKD2 | 0.746312 | 3 | 0 | 3 |
| FBXO30 | DOCK3 | 0.743329 | 3 | 0 | 3 |
| FBXO30 | SLC25A4 | 0.742207 | 4 | 0 | 4 |
| FBXO30 | RASSF3 | 0.734661 | 4 | 0 | 3 |
| FBXO30 | RXRG | 0.732762 | 3 | 0 | 3 |
| FBXO30 | PYGM | 0.731999 | 5 | 0 | 4 |
| FBXO30 | PITPNM2 | 0.731652 | 3 | 0 | 3 |
| FBXO30 | GBA2 | 0.731551 | 3 | 0 | 3 |
| FBXO30 | EIF3G | 0.730755 | 3 | 0 | 3 |
For details and further investigation, click here
