| Full name: family with sequence similarity 76 member B | Alias Symbol: MGC33371 | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 143684 | HGNC ID: HGNC:28492 | Ensembl Gene: ENSG00000077458 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM76B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM76B | 143684 | 226753_at | -0.1895 | 0.7944 | |
| GSE26886 | FAM76B | 143684 | 226753_at | 0.1686 | 0.6362 | |
| GSE45670 | FAM76B | 143684 | 226753_at | -0.1082 | 0.5792 | |
| GSE53622 | FAM76B | 143684 | 95781 | 0.3385 | 0.0000 | |
| GSE53624 | FAM76B | 143684 | 95781 | 0.2326 | 0.0194 | |
| GSE63941 | FAM76B | 143684 | 1553749_at | 1.0105 | 0.0179 | |
| GSE77861 | FAM76B | 143684 | 226753_at | 0.7275 | 0.1568 | |
| GSE97050 | FAM76B | 143684 | A_32_P19752 | 0.0806 | 0.7628 | |
| SRP007169 | FAM76B | 143684 | RNAseq | 0.8027 | 0.0965 | |
| SRP008496 | FAM76B | 143684 | RNAseq | 1.0279 | 0.0024 | |
| SRP064894 | FAM76B | 143684 | RNAseq | 0.0296 | 0.9268 | |
| SRP133303 | FAM76B | 143684 | RNAseq | 0.1419 | 0.3544 | |
| SRP159526 | FAM76B | 143684 | RNAseq | -0.1878 | 0.5430 | |
| SRP193095 | FAM76B | 143684 | RNAseq | -0.1893 | 0.0463 | |
| SRP219564 | FAM76B | 143684 | RNAseq | -0.0709 | 0.8268 | |
| TCGA | FAM76B | 143684 | RNAseq | 0.0723 | 0.2380 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FAM76B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM76B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM76B | 143684 | 3 | 9 | 18 | |
| GSE20123 | FAM76B | 143684 | 3 | 9 | 18 | |
| GSE43470 | FAM76B | 143684 | 2 | 6 | 35 | |
| GSE46452 | FAM76B | 143684 | 5 | 24 | 30 | |
| GSE47630 | FAM76B | 143684 | 2 | 19 | 19 | |
| GSE54993 | FAM76B | 143684 | 9 | 2 | 59 | |
| GSE54994 | FAM76B | 143684 | 6 | 18 | 29 | |
| GSE60625 | FAM76B | 143684 | 0 | 3 | 8 | |
| GSE74703 | FAM76B | 143684 | 1 | 5 | 30 | |
| GSE74704 | FAM76B | 143684 | 3 | 5 | 12 | |
| TCGA | FAM76B | 143684 | 11 | 42 | 43 |
Total number of gains: 45; Total number of losses: 142; Total Number of normals: 301.
Somatic mutations of FAM76B:
Generating mutation plots.
Highly correlated genes for FAM76B:
Showing top 20/429 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM76B | AGAP1 | 0.824881 | 3 | 0 | 3 |
| FAM76B | RBM18 | 0.807426 | 3 | 0 | 3 |
| FAM76B | MKLN1 | 0.796622 | 3 | 0 | 3 |
| FAM76B | EMB | 0.788059 | 3 | 0 | 3 |
| FAM76B | ERP27 | 0.786833 | 3 | 0 | 3 |
| FAM76B | RBMX2 | 0.783236 | 3 | 0 | 3 |
| FAM76B | KLHL7 | 0.781585 | 3 | 0 | 3 |
| FAM76B | TNRC6B | 0.768323 | 3 | 0 | 3 |
| FAM76B | RSBN1 | 0.763379 | 3 | 0 | 3 |
| FAM76B | DHPS | 0.762882 | 3 | 0 | 3 |
| FAM76B | FAM199X | 0.761946 | 3 | 0 | 3 |
| FAM76B | WEE1 | 0.758063 | 3 | 0 | 3 |
| FAM76B | B3GALNT2 | 0.757399 | 3 | 0 | 3 |
| FAM76B | PKIG | 0.752562 | 3 | 0 | 3 |
| FAM76B | TM2D3 | 0.751854 | 3 | 0 | 3 |
| FAM76B | WWC3 | 0.745307 | 3 | 0 | 3 |
| FAM76B | GHR | 0.742711 | 3 | 0 | 3 |
| FAM76B | UBE3A | 0.741719 | 3 | 0 | 3 |
| FAM76B | ATIC | 0.732907 | 3 | 0 | 3 |
| FAM76B | FAM13A | 0.732465 | 4 | 0 | 4 |
For details and further investigation, click here
