| Full name: zinc finger CCCH-type containing 8 | Alias Symbol: Fliz1 | ||
| Type: protein-coding gene | Cytoband: 2q14.1 | ||
| Entrez ID: 84524 | HGNC ID: HGNC:30941 | Ensembl Gene: ENSG00000144161 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZC3H8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZC3H8 | 84524 | 223506_at | 0.3539 | 0.5448 | |
| GSE26886 | ZC3H8 | 84524 | 223506_at | -0.0156 | 0.9444 | |
| GSE45670 | ZC3H8 | 84524 | 223506_at | 0.5484 | 0.0021 | |
| GSE63941 | ZC3H8 | 84524 | 223506_at | 2.1088 | 0.0016 | |
| GSE77861 | ZC3H8 | 84524 | 223506_at | 0.0840 | 0.6287 | |
| GSE97050 | ZC3H8 | 84524 | A_24_P345540 | 0.0404 | 0.8548 | |
| SRP007169 | ZC3H8 | 84524 | RNAseq | 0.9010 | 0.0429 | |
| SRP008496 | ZC3H8 | 84524 | RNAseq | 0.9487 | 0.0101 | |
| SRP064894 | ZC3H8 | 84524 | RNAseq | 0.0706 | 0.6770 | |
| SRP133303 | ZC3H8 | 84524 | RNAseq | 0.1521 | 0.2036 | |
| SRP159526 | ZC3H8 | 84524 | RNAseq | 0.2316 | 0.3531 | |
| SRP193095 | ZC3H8 | 84524 | RNAseq | -0.0484 | 0.6822 | |
| SRP219564 | ZC3H8 | 84524 | RNAseq | -0.0603 | 0.8851 | |
| TCGA | ZC3H8 | 84524 | RNAseq | 0.3861 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZC3H8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZC3H8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZC3H8 | 84524 | 6 | 2 | 22 | |
| GSE20123 | ZC3H8 | 84524 | 6 | 2 | 22 | |
| GSE43470 | ZC3H8 | 84524 | 3 | 1 | 39 | |
| GSE46452 | ZC3H8 | 84524 | 1 | 4 | 54 | |
| GSE47630 | ZC3H8 | 84524 | 7 | 0 | 33 | |
| GSE54993 | ZC3H8 | 84524 | 0 | 6 | 64 | |
| GSE54994 | ZC3H8 | 84524 | 10 | 0 | 43 | |
| GSE60625 | ZC3H8 | 84524 | 0 | 3 | 8 | |
| GSE74703 | ZC3H8 | 84524 | 3 | 1 | 32 | |
| GSE74704 | ZC3H8 | 84524 | 3 | 2 | 15 | |
| TCGA | ZC3H8 | 84524 | 31 | 5 | 60 |
Total number of gains: 70; Total number of losses: 26; Total Number of normals: 392.
Somatic mutations of ZC3H8:
Generating mutation plots.
Highly correlated genes for ZC3H8:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZC3H8 | NIFK | 0.708966 | 3 | 0 | 3 |
| ZC3H8 | BAZ2A | 0.702714 | 3 | 0 | 3 |
| ZC3H8 | TYW5 | 0.694975 | 3 | 0 | 3 |
| ZC3H8 | PDCD11 | 0.692943 | 3 | 0 | 3 |
| ZC3H8 | VCPKMT | 0.690271 | 3 | 0 | 3 |
| ZC3H8 | TFAP2C | 0.668432 | 4 | 0 | 3 |
| ZC3H8 | POLR2D | 0.659002 | 5 | 0 | 4 |
| ZC3H8 | RPL31 | 0.648517 | 3 | 0 | 3 |
| ZC3H8 | HCN3 | 0.636176 | 3 | 0 | 3 |
| ZC3H8 | MRPS9 | 0.628555 | 5 | 0 | 4 |
| ZC3H8 | GEN1 | 0.627032 | 3 | 0 | 3 |
| ZC3H8 | TCF24 | 0.620807 | 3 | 0 | 3 |
| ZC3H8 | MARVELD3 | 0.620777 | 4 | 0 | 4 |
| ZC3H8 | PPFIA3 | 0.620068 | 4 | 0 | 3 |
| ZC3H8 | KCNK1 | 0.619617 | 4 | 0 | 3 |
| ZC3H8 | TMEM182 | 0.619384 | 4 | 0 | 3 |
| ZC3H8 | MTERF1 | 0.619007 | 4 | 0 | 4 |
| ZC3H8 | PUS1 | 0.617376 | 4 | 0 | 4 |
| ZC3H8 | URI1 | 0.616932 | 5 | 0 | 4 |
| ZC3H8 | CXADR | 0.613964 | 4 | 0 | 3 |
For details and further investigation, click here
