TFAP2C

 

Full name: transcription factor AP-2 gamma Alias Symbol: AP2-GAMMA|ERF1|TFAP2G|hAP-2g
Type: protein-coding gene Cytoband: 20q13.31
Entrez ID: 7022 HGNC ID: HGNC:11744 Ensembl Gene: ENSG00000087510 OMIM ID: 601602
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TFAP2C:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TFAP2C 7022 205286_at 0.6425 0.3937
GSE20347 TFAP2C 7022 205286_at -0.1590 0.5861
GSE23400 TFAP2C 7022 205286_at 0.3306 0.0022
GSE26886 TFAP2C 7022 205286_at -0.4401 0.0562
GSE29001 TFAP2C 7022 205286_at 0.2181 0.2877
GSE38129 TFAP2C 7022 205286_at 0.6026 0.1664
GSE45670 TFAP2C 7022 205286_at 0.3509 0.0642
GSE53622 TFAP2C 7022 89614 0.3601 0.0501
GSE53624 TFAP2C 7022 89614 -0.0272 0.7629
GSE63941 TFAP2C 7022 205286_at 4.7881 0.0000
GSE77861 TFAP2C 7022 205286_at 0.0908 0.7133
GSE97050 TFAP2C 7022 A_23_P120472 0.4234 0.2622
SRP007169 TFAP2C 7022 RNAseq -1.3663 0.0018
SRP008496 TFAP2C 7022 RNAseq -1.1634 0.0000
SRP064894 TFAP2C 7022 RNAseq 0.0130 0.9720
SRP133303 TFAP2C 7022 RNAseq -0.0721 0.7577
SRP159526 TFAP2C 7022 RNAseq 0.6583 0.3245
SRP219564 TFAP2C 7022 RNAseq 0.0730 0.9425
TCGA TFAP2C 7022 RNAseq 1.2805 0.0000

Upregulated datasets: 2; Downregulated datasets: 2.  

 

Survival by TFAP2C expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TFAP2C:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TFAP2C 7022 14 2 14
GSE20123 TFAP2C 7022 14 2 14
GSE43470 TFAP2C 7022 14 0 29
GSE46452 TFAP2C 7022 29 0 30
GSE47630 TFAP2C 7022 24 1 15
GSE54993 TFAP2C 7022 0 17 53
GSE54994 TFAP2C 7022 27 0 26
GSE60625 TFAP2C 7022 0 0 11
GSE74703 TFAP2C 7022 12 0 24
GSE74704 TFAP2C 7022 11 0 9
TCGA TFAP2C 7022 43 4 49

Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.  

 

Somatic mutations of TFAP2C:

 

Generating mutation plots.

 

Highly correlated genes for TFAP2C:

 

Showing top 20/261 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TFAP2CEML20.752008303
TFAP2CBMP8B0.749723303
TFAP2CRIPK40.733316404
TFAP2CWRAP730.712068303
TFAP2CMETTL180.703516303
TFAP2CTFAP2E0.699654303
TFAP2CHOXC90.699151303
TFAP2CZNF2830.699023303
TFAP2CDLK20.698435303
TFAP2CHECTD10.697493303
TFAP2CARFGEF10.695807403
TFAP2CPDCD110.692869404
TFAP2CCNOT30.687686303
TFAP2CPPP1R13L0.686099303
TFAP2CTACSTD20.684878505
TFAP2CIRX30.683372403
TFAP2CSULT2B10.682953303
TFAP2CCLDN40.682645403
TFAP2CPRKCZ0.682073403
TFAP2CHAUS50.672894303

For details and further investigation, click here