| Full name: CXADR Ig-like cell adhesion molecule | Alias Symbol: CAR | ||
| Type: protein-coding gene | Cytoband: 21q21.1 | ||
| Entrez ID: 1525 | HGNC ID: HGNC:2559 | Ensembl Gene: ENSG00000154639 | OMIM ID: 602621 |
| Drug and gene relationship at DGIdb | |||
Expression of CXADR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CXADR | 1525 | 203917_at | 0.4398 | 0.6264 | |
| GSE20347 | CXADR | 1525 | 203917_at | -0.1995 | 0.4247 | |
| GSE23400 | CXADR | 1525 | 203917_at | 0.2840 | 0.0361 | |
| GSE26886 | CXADR | 1525 | 203917_at | -0.0110 | 0.9754 | |
| GSE29001 | CXADR | 1525 | 203917_at | -0.0115 | 0.9813 | |
| GSE38129 | CXADR | 1525 | 203917_at | 0.5851 | 0.1782 | |
| GSE45670 | CXADR | 1525 | 203917_at | 0.5405 | 0.0454 | |
| GSE53622 | CXADR | 1525 | 21531 | 0.3087 | 0.0782 | |
| GSE53624 | CXADR | 1525 | 124802 | -0.2878 | 0.0148 | |
| GSE63941 | CXADR | 1525 | 203917_at | 5.4210 | 0.0000 | |
| GSE77861 | CXADR | 1525 | 203917_at | 0.1035 | 0.7768 | |
| GSE97050 | CXADR | 1525 | A_24_P374943 | 0.8824 | 0.3051 | |
| SRP007169 | CXADR | 1525 | RNAseq | -1.0286 | 0.0152 | |
| SRP008496 | CXADR | 1525 | RNAseq | -0.5906 | 0.0932 | |
| SRP064894 | CXADR | 1525 | RNAseq | 0.1535 | 0.6387 | |
| SRP133303 | CXADR | 1525 | RNAseq | -0.1889 | 0.6687 | |
| SRP159526 | CXADR | 1525 | RNAseq | -0.1150 | 0.7660 | |
| SRP193095 | CXADR | 1525 | RNAseq | -0.7250 | 0.0000 | |
| SRP219564 | CXADR | 1525 | RNAseq | -1.0580 | 0.1598 | |
| TCGA | CXADR | 1525 | RNAseq | -0.0339 | 0.7676 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by CXADR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CXADR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CXADR | 1525 | 1 | 9 | 20 | |
| GSE20123 | CXADR | 1525 | 1 | 9 | 20 | |
| GSE43470 | CXADR | 1525 | 1 | 11 | 31 | |
| GSE46452 | CXADR | 1525 | 1 | 22 | 36 | |
| GSE47630 | CXADR | 1525 | 6 | 17 | 17 | |
| GSE54993 | CXADR | 1525 | 9 | 2 | 59 | |
| GSE54994 | CXADR | 1525 | 3 | 10 | 40 | |
| GSE60625 | CXADR | 1525 | 0 | 0 | 11 | |
| GSE74703 | CXADR | 1525 | 1 | 8 | 27 | |
| GSE74704 | CXADR | 1525 | 1 | 6 | 13 | |
| TCGA | CXADR | 1525 | 10 | 42 | 44 |
Total number of gains: 34; Total number of losses: 136; Total Number of normals: 318.
Somatic mutations of CXADR:
Generating mutation plots.
Highly correlated genes for CXADR:
Showing top 20/343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CXADR | SPINT1 | 0.798033 | 3 | 0 | 3 |
| CXADR | FAM83H | 0.757381 | 4 | 0 | 4 |
| CXADR | RNF149 | 0.739512 | 4 | 0 | 3 |
| CXADR | E2F2 | 0.730001 | 3 | 0 | 3 |
| CXADR | STAP2 | 0.729231 | 4 | 0 | 4 |
| CXADR | FAM160A1 | 0.721864 | 3 | 0 | 3 |
| CXADR | CDS1 | 0.717883 | 5 | 0 | 5 |
| CXADR | ESRP1 | 0.708954 | 7 | 0 | 5 |
| CXADR | LAD1 | 0.708577 | 6 | 0 | 6 |
| CXADR | C1orf210 | 0.701879 | 3 | 0 | 3 |
| CXADR | PTPN3 | 0.690721 | 4 | 0 | 4 |
| CXADR | CAMSAP3 | 0.689597 | 3 | 0 | 3 |
| CXADR | SYTL1 | 0.686632 | 4 | 0 | 3 |
| CXADR | BUB3 | 0.685933 | 4 | 0 | 3 |
| CXADR | BAIAP2L1 | 0.683562 | 5 | 0 | 4 |
| CXADR | TTK | 0.683513 | 5 | 0 | 5 |
| CXADR | PTBP3 | 0.680638 | 6 | 0 | 5 |
| CXADR | MARVELD2 | 0.680478 | 6 | 0 | 5 |
| CXADR | EPCAM | 0.67723 | 4 | 0 | 3 |
| CXADR | MAP7 | 0.675863 | 8 | 0 | 6 |
For details and further investigation, click here
