POLR2D

 

Full name: RNA polymerase II subunit D Alias Symbol: RBP4
Type: protein-coding gene Cytoband: 2q14.3
Entrez ID: 5433 HGNC ID: HGNC:9191 Ensembl Gene: ENSG00000144231 OMIM ID: 606017
Drug and gene relationship at DGIdb

 

Expression of POLR2D:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POLR2D 5433 203664_s_at 0.9757 0.0189
GSE20347 POLR2D 5433 203664_s_at 0.7891 0.0002
GSE23400 POLR2D 5433 203664_s_at 0.4781 0.0000
GSE26886 POLR2D 5433 203664_s_at -0.0009 0.9965
GSE29001 POLR2D 5433 203664_s_at 0.7632 0.0169
GSE38129 POLR2D 5433 214144_at 0.7461 0.0000
GSE45670 POLR2D 5433 203664_s_at 0.7186 0.0005
GSE53622 POLR2D 5433 31186 0.6720 0.0000
GSE53624 POLR2D 5433 31186 0.7901 0.0000
GSE63941 POLR2D 5433 203664_s_at 1.3614 0.0010
GSE77861 POLR2D 5433 203664_s_at 0.5158 0.0102
GSE97050 POLR2D 5433 A_23_P209778 0.4273 0.2252
SRP007169 POLR2D 5433 RNAseq 1.3548 0.0005
SRP008496 POLR2D 5433 RNAseq 1.2335 0.0000
SRP064894 POLR2D 5433 RNAseq 0.6015 0.0000
SRP133303 POLR2D 5433 RNAseq 0.5359 0.0000
SRP159526 POLR2D 5433 RNAseq 0.9263 0.0004
SRP193095 POLR2D 5433 RNAseq 0.3324 0.0001
SRP219564 POLR2D 5433 RNAseq 0.1435 0.5154
TCGA POLR2D 5433 RNAseq 0.2018 0.0003

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by POLR2D expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of POLR2D:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POLR2D 5433 6 3 21
GSE20123 POLR2D 5433 6 3 21
GSE43470 POLR2D 5433 2 1 40
GSE46452 POLR2D 5433 1 3 55
GSE47630 POLR2D 5433 6 0 34
GSE54993 POLR2D 5433 0 6 64
GSE54994 POLR2D 5433 11 0 42
GSE60625 POLR2D 5433 0 3 8
GSE74703 POLR2D 5433 2 1 33
GSE74704 POLR2D 5433 3 1 16
TCGA POLR2D 5433 22 8 66

Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.  

 

Somatic mutations of POLR2D:

 

Generating mutation plots.

 

Highly correlated genes for POLR2D:

 

Showing top 20/1716 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POLR2DCKAP2L0.772706707
POLR2DSNAP470.76803303
POLR2DFEN10.764777606
POLR2DCENPBD10.758815303
POLR2DTTL0.757958606
POLR2DRUVBL10.7518912011
POLR2DNIFK0.751537606
POLR2DPNO10.751102707
POLR2DKNSTRN0.744851606
POLR2DSIX40.741332606
POLR2DERCC30.73847412012
POLR2DIMP40.7383612011
POLR2DPYCR20.734745303
POLR2DUBE2T0.730566807
POLR2DAURKB0.72571511011
POLR2DCAD0.72529411011
POLR2DRFC40.72272612011
POLR2DPFDN20.72243111011
POLR2DRNASEH2A0.72155611011
POLR2DNUF20.721236707

For details and further investigation, click here