| Full name: nucleolar protein interacting with the FHA domain of MKI67 | Alias Symbol: Nopp34|hNIFK | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 84365 | HGNC ID: HGNC:17838 | Ensembl Gene: ENSG00000155438 | OMIM ID: 611970 |
| Drug and gene relationship at DGIdb | |||
Expression of NIFK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NIFK | 84365 | 224714_at | 0.8991 | 0.0560 | |
| GSE26886 | NIFK | 84365 | 224714_at | 1.1043 | 0.0000 | |
| GSE45670 | NIFK | 84365 | 224714_at | 0.7277 | 0.0002 | |
| GSE53622 | NIFK | 84365 | 50037 | 0.7164 | 0.0000 | |
| GSE53624 | NIFK | 84365 | 50037 | 0.8570 | 0.0000 | |
| GSE63941 | NIFK | 84365 | 224714_at | 0.7355 | 0.1169 | |
| GSE77861 | NIFK | 84365 | 224714_at | 0.7619 | 0.0150 | |
| SRP007169 | NIFK | 84365 | RNAseq | 0.9747 | 0.0365 | |
| SRP008496 | NIFK | 84365 | RNAseq | 0.9869 | 0.0032 | |
| SRP064894 | NIFK | 84365 | RNAseq | 0.2743 | 0.0975 | |
| SRP133303 | NIFK | 84365 | RNAseq | 0.7372 | 0.0000 | |
| SRP159526 | NIFK | 84365 | RNAseq | 0.1852 | 0.5228 | |
| SRP193095 | NIFK | 84365 | RNAseq | 0.1784 | 0.2923 | |
| SRP219564 | NIFK | 84365 | RNAseq | 0.0690 | 0.8275 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NIFK expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NIFK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NIFK | 84365 | 6 | 2 | 22 | |
| GSE20123 | NIFK | 84365 | 6 | 2 | 22 | |
| GSE43470 | NIFK | 84365 | 3 | 1 | 39 | |
| GSE46452 | NIFK | 84365 | 1 | 3 | 55 | |
| GSE47630 | NIFK | 84365 | 6 | 0 | 34 | |
| GSE54993 | NIFK | 84365 | 0 | 6 | 64 | |
| GSE54994 | NIFK | 84365 | 12 | 0 | 41 | |
| GSE60625 | NIFK | 84365 | 0 | 3 | 8 | |
| GSE74703 | NIFK | 84365 | 3 | 1 | 32 | |
| GSE74704 | NIFK | 84365 | 3 | 1 | 16 |
Total number of gains: 40; Total number of losses: 19; Total Number of normals: 333.
Somatic mutations of NIFK:
Generating mutation plots.
Highly correlated genes for NIFK:
Showing top 20/1454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NIFK | PTRH2 | 0.798239 | 7 | 0 | 7 |
| NIFK | WDHD1 | 0.784218 | 6 | 0 | 6 |
| NIFK | U2SURP | 0.782797 | 4 | 0 | 4 |
| NIFK | BMS1 | 0.765398 | 4 | 0 | 4 |
| NIFK | DNAJC2 | 0.76323 | 6 | 0 | 6 |
| NIFK | CDKN3 | 0.757327 | 6 | 0 | 6 |
| NIFK | POLR2D | 0.751537 | 6 | 0 | 6 |
| NIFK | PSME4 | 0.745864 | 6 | 0 | 6 |
| NIFK | IMP4 | 0.741438 | 7 | 0 | 7 |
| NIFK | UGGT1 | 0.737511 | 4 | 0 | 4 |
| NIFK | KPNA2 | 0.737137 | 4 | 0 | 4 |
| NIFK | CENPI | 0.736295 | 6 | 0 | 6 |
| NIFK | PRPF40A | 0.735245 | 6 | 0 | 6 |
| NIFK | HJURP | 0.733327 | 5 | 0 | 5 |
| NIFK | RACGAP1 | 0.732665 | 4 | 0 | 4 |
| NIFK | BUB1 | 0.730322 | 6 | 0 | 6 |
| NIFK | SCYL1 | 0.728846 | 4 | 0 | 4 |
| NIFK | CMSS1 | 0.723334 | 7 | 0 | 7 |
| NIFK | RFWD3 | 0.723074 | 5 | 0 | 5 |
| NIFK | ECT2 | 0.722338 | 6 | 0 | 6 |
For details and further investigation, click here
