| Full name: mitochondrial ribosomal protein S9 | Alias Symbol: RPMS9|MRP-S9|S9mt | ||
| Type: protein-coding gene | Cytoband: 2q12.1 | ||
| Entrez ID: 64965 | HGNC ID: HGNC:14501 | Ensembl Gene: ENSG00000135972 | OMIM ID: 611975 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS9 | 64965 | 226749_at | 0.5209 | 0.2254 | |
| GSE26886 | MRPS9 | 64965 | 226749_at | 0.4993 | 0.0351 | |
| GSE45670 | MRPS9 | 64965 | 226749_at | 0.1436 | 0.4236 | |
| GSE53622 | MRPS9 | 64965 | 144418 | -0.0555 | 0.4105 | |
| GSE53624 | MRPS9 | 64965 | 144418 | 0.2248 | 0.0000 | |
| GSE63941 | MRPS9 | 64965 | 226749_at | -0.0483 | 0.9254 | |
| GSE77861 | MRPS9 | 64965 | 226749_at | 0.1538 | 0.5391 | |
| GSE97050 | MRPS9 | 64965 | A_23_P154315 | -0.0707 | 0.8218 | |
| SRP007169 | MRPS9 | 64965 | RNAseq | 0.9400 | 0.0572 | |
| SRP008496 | MRPS9 | 64965 | RNAseq | 1.3342 | 0.0024 | |
| SRP064894 | MRPS9 | 64965 | RNAseq | 0.0282 | 0.8673 | |
| SRP133303 | MRPS9 | 64965 | RNAseq | 0.1815 | 0.1308 | |
| SRP159526 | MRPS9 | 64965 | RNAseq | 0.3403 | 0.3065 | |
| SRP193095 | MRPS9 | 64965 | RNAseq | -0.1120 | 0.4219 | |
| SRP219564 | MRPS9 | 64965 | RNAseq | -0.3388 | 0.2591 | |
| TCGA | MRPS9 | 64965 | RNAseq | 0.0062 | 0.9102 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPS9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS9 | 64965 | 3 | 2 | 25 | |
| GSE20123 | MRPS9 | 64965 | 3 | 2 | 25 | |
| GSE43470 | MRPS9 | 64965 | 3 | 1 | 39 | |
| GSE46452 | MRPS9 | 64965 | 1 | 4 | 54 | |
| GSE47630 | MRPS9 | 64965 | 7 | 0 | 33 | |
| GSE54993 | MRPS9 | 64965 | 0 | 6 | 64 | |
| GSE54994 | MRPS9 | 64965 | 10 | 0 | 43 | |
| GSE60625 | MRPS9 | 64965 | 0 | 3 | 8 | |
| GSE74703 | MRPS9 | 64965 | 3 | 1 | 32 | |
| GSE74704 | MRPS9 | 64965 | 2 | 2 | 16 | |
| TCGA | MRPS9 | 64965 | 35 | 5 | 56 |
Total number of gains: 67; Total number of losses: 26; Total Number of normals: 395.
Somatic mutations of MRPS9:
Generating mutation plots.
Highly correlated genes for MRPS9:
Showing top 20/544 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS9 | RPL7L1 | 0.816673 | 3 | 0 | 3 |
| MRPS9 | DCAF16 | 0.811966 | 3 | 0 | 3 |
| MRPS9 | SETD6 | 0.786386 | 3 | 0 | 3 |
| MRPS9 | POLR1B | 0.762269 | 4 | 0 | 4 |
| MRPS9 | MRPL1 | 0.760799 | 3 | 0 | 3 |
| MRPS9 | SRPK2 | 0.759055 | 3 | 0 | 3 |
| MRPS9 | MMS19 | 0.758862 | 3 | 0 | 3 |
| MRPS9 | CTBP2 | 0.756266 | 3 | 0 | 3 |
| MRPS9 | EHMT2 | 0.753228 | 3 | 0 | 3 |
| MRPS9 | CRCP | 0.750449 | 3 | 0 | 3 |
| MRPS9 | GPATCH1 | 0.749725 | 3 | 0 | 3 |
| MRPS9 | RPL8 | 0.749412 | 3 | 0 | 3 |
| MRPS9 | IGF2R | 0.743746 | 3 | 0 | 3 |
| MRPS9 | PRPF4B | 0.738833 | 3 | 0 | 3 |
| MRPS9 | QSOX2 | 0.734949 | 3 | 0 | 3 |
| MRPS9 | THUMPD2 | 0.729275 | 3 | 0 | 3 |
| MRPS9 | NPHP3 | 0.72899 | 3 | 0 | 3 |
| MRPS9 | RAE1 | 0.722539 | 3 | 0 | 3 |
| MRPS9 | AATF | 0.721882 | 4 | 0 | 3 |
| MRPS9 | LRP5L | 0.720951 | 3 | 0 | 3 |
For details and further investigation, click here
