| Full name: programmed cell death 11 | Alias Symbol: KIAA0185|ALG-4|RRP5|NFBP | ||
| Type: protein-coding gene | Cytoband: 10q24.33 | ||
| Entrez ID: 22984 | HGNC ID: HGNC:13408 | Ensembl Gene: ENSG00000148843 | OMIM ID: 612333 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PDCD11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCD11 | 22984 | 212422_at | 0.8146 | 0.0633 | |
| GSE20347 | PDCD11 | 22984 | 212422_at | 0.1936 | 0.0433 | |
| GSE23400 | PDCD11 | 22984 | 212424_at | 0.0231 | 0.7218 | |
| GSE26886 | PDCD11 | 22984 | 212424_at | 0.5799 | 0.0017 | |
| GSE29001 | PDCD11 | 22984 | 212424_at | 0.2646 | 0.1477 | |
| GSE38129 | PDCD11 | 22984 | 212424_at | 0.3247 | 0.0073 | |
| GSE45670 | PDCD11 | 22984 | 212424_at | 0.4311 | 0.0004 | |
| GSE53622 | PDCD11 | 22984 | 117814 | 0.3098 | 0.0022 | |
| GSE53624 | PDCD11 | 22984 | 117814 | 0.4547 | 0.0000 | |
| GSE63941 | PDCD11 | 22984 | 212424_at | -0.1442 | 0.6808 | |
| GSE77861 | PDCD11 | 22984 | 212424_at | 0.0735 | 0.6642 | |
| GSE97050 | PDCD11 | 22984 | A_33_P3361182 | 0.2958 | 0.2533 | |
| SRP007169 | PDCD11 | 22984 | RNAseq | 1.0697 | 0.0303 | |
| SRP008496 | PDCD11 | 22984 | RNAseq | 1.0778 | 0.0012 | |
| SRP064894 | PDCD11 | 22984 | RNAseq | 0.1282 | 0.3883 | |
| SRP133303 | PDCD11 | 22984 | RNAseq | 0.2556 | 0.0664 | |
| SRP159526 | PDCD11 | 22984 | RNAseq | 0.1881 | 0.4221 | |
| SRP193095 | PDCD11 | 22984 | RNAseq | 0.4542 | 0.0002 | |
| SRP219564 | PDCD11 | 22984 | RNAseq | 0.3704 | 0.3822 | |
| TCGA | PDCD11 | 22984 | RNAseq | 0.1166 | 0.0197 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PDCD11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCD11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCD11 | 22984 | 2 | 9 | 19 | |
| GSE20123 | PDCD11 | 22984 | 2 | 8 | 20 | |
| GSE43470 | PDCD11 | 22984 | 0 | 8 | 35 | |
| GSE46452 | PDCD11 | 22984 | 0 | 11 | 48 | |
| GSE47630 | PDCD11 | 22984 | 2 | 14 | 24 | |
| GSE54993 | PDCD11 | 22984 | 8 | 0 | 62 | |
| GSE54994 | PDCD11 | 22984 | 1 | 10 | 42 | |
| GSE60625 | PDCD11 | 22984 | 0 | 0 | 11 | |
| GSE74703 | PDCD11 | 22984 | 0 | 5 | 31 | |
| GSE74704 | PDCD11 | 22984 | 1 | 4 | 15 | |
| TCGA | PDCD11 | 22984 | 6 | 28 | 62 |
Total number of gains: 22; Total number of losses: 97; Total Number of normals: 369.
Somatic mutations of PDCD11:
Generating mutation plots.
Highly correlated genes for PDCD11:
Showing top 20/430 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCD11 | PODXL2 | 0.771776 | 3 | 0 | 3 |
| PDCD11 | HRK | 0.767501 | 3 | 0 | 3 |
| PDCD11 | POR | 0.726862 | 3 | 0 | 3 |
| PDCD11 | TRIM11 | 0.724637 | 4 | 0 | 4 |
| PDCD11 | COL27A1 | 0.710802 | 4 | 0 | 4 |
| PDCD11 | BEND3 | 0.709374 | 5 | 0 | 4 |
| PDCD11 | USP49 | 0.708543 | 3 | 0 | 3 |
| PDCD11 | HIVEP2 | 0.706184 | 3 | 0 | 3 |
| PDCD11 | ZC3H8 | 0.692943 | 3 | 0 | 3 |
| PDCD11 | TFAP2C | 0.692869 | 4 | 0 | 4 |
| PDCD11 | POC1A | 0.679057 | 5 | 0 | 5 |
| PDCD11 | ZNF77 | 0.678754 | 5 | 0 | 4 |
| PDCD11 | HOXD10 | 0.676144 | 4 | 0 | 4 |
| PDCD11 | ZBTB17 | 0.672267 | 4 | 0 | 3 |
| PDCD11 | WDR53 | 0.670744 | 5 | 0 | 4 |
| PDCD11 | GTF2IRD2 | 0.670088 | 4 | 0 | 3 |
| PDCD11 | C16orf91 | 0.669666 | 4 | 0 | 3 |
| PDCD11 | HOXC9 | 0.666775 | 4 | 0 | 3 |
| PDCD11 | ANKLE1 | 0.661862 | 3 | 0 | 3 |
| PDCD11 | ELMO3 | 0.661066 | 4 | 0 | 3 |
For details and further investigation, click here
