| Full name: valosin containing protein lysine methyltransferase | Alias Symbol: VCP-KMT | ||
| Type: protein-coding gene | Cytoband: 14q21.3 | ||
| Entrez ID: 79609 | HGNC ID: HGNC:20352 | Ensembl Gene: ENSG00000100483 | OMIM ID: 615260 |
| Drug and gene relationship at DGIdb | |||
Expression of VCPKMT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VCPKMT | 79609 | 218940_at | 0.6868 | 0.4121 | |
| GSE20347 | VCPKMT | 79609 | 218940_at | 0.2089 | 0.2752 | |
| GSE23400 | VCPKMT | 79609 | 218940_at | 0.4220 | 0.0000 | |
| GSE26886 | VCPKMT | 79609 | 218940_at | 0.7552 | 0.0020 | |
| GSE29001 | VCPKMT | 79609 | 218940_at | 0.1474 | 0.7136 | |
| GSE38129 | VCPKMT | 79609 | 218940_at | 0.3325 | 0.0490 | |
| GSE45670 | VCPKMT | 79609 | 218940_at | 0.0213 | 0.9029 | |
| GSE53622 | VCPKMT | 79609 | 46797 | 0.3262 | 0.0001 | |
| GSE53624 | VCPKMT | 79609 | 46797 | 0.1088 | 0.1653 | |
| GSE63941 | VCPKMT | 79609 | 218940_at | 0.7624 | 0.1714 | |
| GSE77861 | VCPKMT | 79609 | 218940_at | 0.4103 | 0.3820 | |
| SRP007169 | VCPKMT | 79609 | RNAseq | -0.2631 | 0.5861 | |
| SRP064894 | VCPKMT | 79609 | RNAseq | 0.0215 | 0.9106 | |
| SRP133303 | VCPKMT | 79609 | RNAseq | 0.1482 | 0.3706 | |
| SRP159526 | VCPKMT | 79609 | RNAseq | -0.1781 | 0.6374 | |
| SRP193095 | VCPKMT | 79609 | RNAseq | -0.1206 | 0.3187 | |
| SRP219564 | VCPKMT | 79609 | RNAseq | 0.1376 | 0.6976 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VCPKMT expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of VCPKMT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VCPKMT | 79609 | 9 | 2 | 19 | |
| GSE20123 | VCPKMT | 79609 | 9 | 3 | 18 | |
| GSE43470 | VCPKMT | 79609 | 8 | 1 | 34 | |
| GSE46452 | VCPKMT | 79609 | 16 | 3 | 40 | |
| GSE47630 | VCPKMT | 79609 | 11 | 10 | 19 | |
| GSE54993 | VCPKMT | 79609 | 3 | 9 | 58 | |
| GSE54994 | VCPKMT | 79609 | 19 | 4 | 30 | |
| GSE60625 | VCPKMT | 79609 | 0 | 2 | 9 | |
| GSE74703 | VCPKMT | 79609 | 7 | 1 | 28 | |
| GSE74704 | VCPKMT | 79609 | 4 | 2 | 14 |
Total number of gains: 86; Total number of losses: 37; Total Number of normals: 269.
Somatic mutations of VCPKMT:
Generating mutation plots.
Highly correlated genes for VCPKMT:
Showing top 20/215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VCPKMT | ZC3H8 | 0.690271 | 3 | 0 | 3 |
| VCPKMT | ING2 | 0.687658 | 3 | 0 | 3 |
| VCPKMT | CTDSPL2 | 0.682061 | 3 | 0 | 3 |
| VCPKMT | CEBPG | 0.669843 | 3 | 0 | 3 |
| VCPKMT | FANCM | 0.649013 | 3 | 0 | 3 |
| VCPKMT | ACTR10 | 0.645203 | 3 | 0 | 3 |
| VCPKMT | KATNA1 | 0.644926 | 3 | 0 | 3 |
| VCPKMT | MTHFD2L | 0.643016 | 3 | 0 | 3 |
| VCPKMT | COCH | 0.640978 | 4 | 0 | 4 |
| VCPKMT | ADAT2 | 0.638388 | 3 | 0 | 3 |
| VCPKMT | ABCD4 | 0.63628 | 4 | 0 | 3 |
| VCPKMT | NOSIP | 0.635654 | 3 | 0 | 3 |
| VCPKMT | PLCG1 | 0.631327 | 3 | 0 | 3 |
| VCPKMT | PTPN4 | 0.629072 | 4 | 0 | 3 |
| VCPKMT | ZMYND19 | 0.625799 | 3 | 0 | 3 |
| VCPKMT | TIMM8A | 0.623272 | 3 | 0 | 3 |
| VCPKMT | ZNF165 | 0.622082 | 4 | 0 | 3 |
| VCPKMT | SUPT3H | 0.615059 | 4 | 0 | 3 |
| VCPKMT | DHX36 | 0.613375 | 3 | 0 | 3 |
| VCPKMT | CHD1 | 0.609549 | 3 | 0 | 3 |
For details and further investigation, click here
