| Full name: solute carrier family 12 member 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 9990 | HGNC ID: HGNC:10914 | Ensembl Gene: ENSG00000140199 | OMIM ID: 604878 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC12A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC12A6 | 9990 | 226741_at | -0.4348 | 0.5825 | |
| GSE20347 | SLC12A6 | 9990 | 220740_s_at | -0.6765 | 0.0221 | |
| GSE23400 | SLC12A6 | 9990 | 220740_s_at | -0.6974 | 0.0000 | |
| GSE26886 | SLC12A6 | 9990 | 226741_at | -1.4732 | 0.0000 | |
| GSE29001 | SLC12A6 | 9990 | 220740_s_at | -1.1278 | 0.0012 | |
| GSE38129 | SLC12A6 | 9990 | 220740_s_at | -0.5580 | 0.0383 | |
| GSE45670 | SLC12A6 | 9990 | 226741_at | -0.3504 | 0.1357 | |
| GSE63941 | SLC12A6 | 9990 | 226741_at | 0.0534 | 0.9167 | |
| GSE77861 | SLC12A6 | 9990 | 226741_at | -0.4799 | 0.1302 | |
| GSE97050 | SLC12A6 | 9990 | A_33_P3212112 | -0.3633 | 0.2018 | |
| SRP007169 | SLC12A6 | 9990 | RNAseq | -0.7685 | 0.1750 | |
| SRP008496 | SLC12A6 | 9990 | RNAseq | -1.0906 | 0.0015 | |
| SRP064894 | SLC12A6 | 9990 | RNAseq | -1.6463 | 0.0000 | |
| SRP133303 | SLC12A6 | 9990 | RNAseq | -0.7922 | 0.0000 | |
| SRP159526 | SLC12A6 | 9990 | RNAseq | -0.7168 | 0.2480 | |
| SRP193095 | SLC12A6 | 9990 | RNAseq | -0.7360 | 0.0006 | |
| SRP219564 | SLC12A6 | 9990 | RNAseq | -1.8246 | 0.0054 | |
| TCGA | SLC12A6 | 9990 | RNAseq | 0.1467 | 0.0682 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SLC12A6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SLC12A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC12A6 | 9990 | 3 | 6 | 21 | |
| GSE20123 | SLC12A6 | 9990 | 3 | 6 | 21 | |
| GSE43470 | SLC12A6 | 9990 | 4 | 4 | 35 | |
| GSE46452 | SLC12A6 | 9990 | 3 | 7 | 49 | |
| GSE47630 | SLC12A6 | 9990 | 8 | 11 | 21 | |
| GSE54993 | SLC12A6 | 9990 | 4 | 6 | 60 | |
| GSE54994 | SLC12A6 | 9990 | 5 | 8 | 40 | |
| GSE60625 | SLC12A6 | 9990 | 4 | 0 | 7 | |
| GSE74703 | SLC12A6 | 9990 | 4 | 3 | 29 | |
| GSE74704 | SLC12A6 | 9990 | 2 | 5 | 13 | |
| TCGA | SLC12A6 | 9990 | 13 | 18 | 65 |
Total number of gains: 53; Total number of losses: 74; Total Number of normals: 361.
Somatic mutations of SLC12A6:
Generating mutation plots.
Highly correlated genes for SLC12A6:
Showing top 20/1375 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC12A6 | FAM3B | 0.824692 | 3 | 0 | 3 |
| SLC12A6 | UQCRC2 | 0.8159 | 3 | 0 | 3 |
| SLC12A6 | TP53INP2 | 0.804113 | 3 | 0 | 3 |
| SLC12A6 | RAB10 | 0.798494 | 4 | 0 | 4 |
| SLC12A6 | ZNF506 | 0.79452 | 3 | 0 | 3 |
| SLC12A6 | USP54 | 0.794474 | 4 | 0 | 4 |
| SLC12A6 | DDX3X | 0.790531 | 3 | 0 | 3 |
| SLC12A6 | ZNF175 | 0.788726 | 3 | 0 | 3 |
| SLC12A6 | COMMD8 | 0.784395 | 3 | 0 | 3 |
| SLC12A6 | AKIRIN2 | 0.783117 | 3 | 0 | 3 |
| SLC12A6 | ULK3 | 0.781931 | 5 | 0 | 5 |
| SLC12A6 | CAPN14 | 0.779054 | 4 | 0 | 4 |
| SLC12A6 | MUC15 | 0.77905 | 4 | 0 | 4 |
| SLC12A6 | PITHD1 | 0.774827 | 3 | 0 | 3 |
| SLC12A6 | PCGF3 | 0.774457 | 3 | 0 | 3 |
| SLC12A6 | LYRM7 | 0.771096 | 3 | 0 | 3 |
| SLC12A6 | UBE2A | 0.770462 | 3 | 0 | 3 |
| SLC12A6 | WDR61 | 0.764814 | 3 | 0 | 3 |
| SLC12A6 | COPS4 | 0.762879 | 3 | 0 | 3 |
| SLC12A6 | SNX33 | 0.761047 | 3 | 0 | 3 |
For details and further investigation, click here
