| Full name: zinc finger matrin-type 3 | Alias Symbol: WIG1|MGC10613|FLJ12296|WIG-1|PAG608 | ||
| Type: protein-coding gene | Cytoband: 3q26.32 | ||
| Entrez ID: 64393 | HGNC ID: HGNC:29983 | Ensembl Gene: ENSG00000172667 | OMIM ID: 606452 |
| Drug and gene relationship at DGIdb | |||
ZMAT3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04115 | p53 signaling pathway |
Expression of ZMAT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZMAT3 | 64393 | 228315_at | -0.0222 | 0.9779 | |
| GSE20347 | ZMAT3 | 64393 | 219628_at | -0.0209 | 0.9150 | |
| GSE23400 | ZMAT3 | 64393 | 219628_at | -0.0053 | 0.9380 | |
| GSE26886 | ZMAT3 | 64393 | 225725_at | -0.3523 | 0.2047 | |
| GSE29001 | ZMAT3 | 64393 | 219628_at | -0.2099 | 0.4811 | |
| GSE38129 | ZMAT3 | 64393 | 219628_at | -0.0670 | 0.6847 | |
| GSE45670 | ZMAT3 | 64393 | 228315_at | 0.0795 | 0.7392 | |
| GSE63941 | ZMAT3 | 64393 | 225725_at | -3.6854 | 0.0000 | |
| GSE77861 | ZMAT3 | 64393 | 225725_at | -0.0703 | 0.7540 | |
| GSE97050 | ZMAT3 | 64393 | A_23_P113283 | 0.3632 | 0.2501 | |
| SRP007169 | ZMAT3 | 64393 | RNAseq | 1.5617 | 0.0172 | |
| SRP008496 | ZMAT3 | 64393 | RNAseq | 1.5770 | 0.0000 | |
| SRP064894 | ZMAT3 | 64393 | RNAseq | 0.5430 | 0.0037 | |
| SRP133303 | ZMAT3 | 64393 | RNAseq | 0.4662 | 0.0009 | |
| SRP159526 | ZMAT3 | 64393 | RNAseq | 1.0299 | 0.0079 | |
| SRP193095 | ZMAT3 | 64393 | RNAseq | 0.0748 | 0.5132 | |
| SRP219564 | ZMAT3 | 64393 | RNAseq | -0.0485 | 0.9252 | |
| TCGA | ZMAT3 | 64393 | RNAseq | -0.0547 | 0.4896 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ZMAT3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZMAT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZMAT3 | 64393 | 25 | 0 | 5 | |
| GSE20123 | ZMAT3 | 64393 | 25 | 0 | 5 | |
| GSE43470 | ZMAT3 | 64393 | 24 | 0 | 19 | |
| GSE46452 | ZMAT3 | 64393 | 19 | 1 | 39 | |
| GSE47630 | ZMAT3 | 64393 | 27 | 2 | 11 | |
| GSE54993 | ZMAT3 | 64393 | 1 | 18 | 51 | |
| GSE54994 | ZMAT3 | 64393 | 41 | 0 | 12 | |
| GSE60625 | ZMAT3 | 64393 | 0 | 6 | 5 | |
| GSE74703 | ZMAT3 | 64393 | 20 | 0 | 16 | |
| GSE74704 | ZMAT3 | 64393 | 16 | 0 | 4 | |
| TCGA | ZMAT3 | 64393 | 78 | 0 | 18 |
Total number of gains: 276; Total number of losses: 27; Total Number of normals: 185.
Somatic mutations of ZMAT3:
Generating mutation plots.
Highly correlated genes for ZMAT3:
Showing top 20/272 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZMAT3 | ANKRD44 | 0.802712 | 4 | 0 | 4 |
| ZMAT3 | TMOD2 | 0.797025 | 3 | 0 | 3 |
| ZMAT3 | ZNF570 | 0.777751 | 3 | 0 | 3 |
| ZMAT3 | RRM2B | 0.772108 | 3 | 0 | 3 |
| ZMAT3 | KBTBD6 | 0.770144 | 3 | 0 | 3 |
| ZMAT3 | TRIM8 | 0.768475 | 3 | 0 | 3 |
| ZMAT3 | PNPLA8 | 0.767182 | 3 | 0 | 3 |
| ZMAT3 | ZNF25 | 0.765319 | 3 | 0 | 3 |
| ZMAT3 | ZMPSTE24 | 0.762924 | 3 | 0 | 3 |
| ZMAT3 | SNX18 | 0.753257 | 3 | 0 | 3 |
| ZMAT3 | NTAN1 | 0.750027 | 3 | 0 | 3 |
| ZMAT3 | KBTBD7 | 0.7492 | 3 | 0 | 3 |
| ZMAT3 | FKBP7 | 0.743802 | 3 | 0 | 3 |
| ZMAT3 | EZH1 | 0.741678 | 3 | 0 | 3 |
| ZMAT3 | CHUK | 0.741068 | 3 | 0 | 3 |
| ZMAT3 | VPS26B | 0.735912 | 3 | 0 | 3 |
| ZMAT3 | ZNF583 | 0.735054 | 3 | 0 | 3 |
| ZMAT3 | ZNF322 | 0.731764 | 3 | 0 | 3 |
| ZMAT3 | IMPAD1 | 0.730169 | 3 | 0 | 3 |
| ZMAT3 | FBXW2 | 0.728112 | 3 | 0 | 3 |
For details and further investigation, click here
