| Full name: anoctamin 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 57719 | HGNC ID: HGNC:29329 | Ensembl Gene: ENSG00000074855 | OMIM ID: 610216 |
| Drug and gene relationship at DGIdb | |||
Expression of ANO8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO8 | 57719 | 1563549_a_at | -0.1970 | 0.6832 | |
| GSE26886 | ANO8 | 57719 | 1563549_a_at | -0.5439 | 0.0007 | |
| GSE45670 | ANO8 | 57719 | 1563549_a_at | -0.2360 | 0.1262 | |
| GSE63941 | ANO8 | 57719 | 1563549_a_at | 0.3420 | 0.2219 | |
| GSE77861 | ANO8 | 57719 | 1563549_a_at | -0.4213 | 0.1012 | |
| GSE97050 | ANO8 | 57719 | A_32_P73452 | -0.4387 | 0.1189 | |
| SRP007169 | ANO8 | 57719 | RNAseq | -2.5627 | 0.0000 | |
| SRP008496 | ANO8 | 57719 | RNAseq | -2.7249 | 0.0000 | |
| SRP064894 | ANO8 | 57719 | RNAseq | -1.1069 | 0.0001 | |
| SRP133303 | ANO8 | 57719 | RNAseq | -1.2941 | 0.0000 | |
| SRP159526 | ANO8 | 57719 | RNAseq | -0.9938 | 0.0130 | |
| SRP193095 | ANO8 | 57719 | RNAseq | -0.6788 | 0.0043 | |
| SRP219564 | ANO8 | 57719 | RNAseq | -0.6522 | 0.2380 | |
| TCGA | ANO8 | 57719 | RNAseq | -0.2533 | 0.0038 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ANO8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ANO8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO8 | 57719 | 4 | 4 | 22 | |
| GSE20123 | ANO8 | 57719 | 3 | 2 | 25 | |
| GSE43470 | ANO8 | 57719 | 2 | 6 | 35 | |
| GSE46452 | ANO8 | 57719 | 47 | 1 | 11 | |
| GSE47630 | ANO8 | 57719 | 4 | 8 | 28 | |
| GSE54993 | ANO8 | 57719 | 15 | 4 | 51 | |
| GSE54994 | ANO8 | 57719 | 6 | 14 | 33 | |
| GSE60625 | ANO8 | 57719 | 9 | 0 | 2 | |
| GSE74703 | ANO8 | 57719 | 2 | 4 | 30 | |
| GSE74704 | ANO8 | 57719 | 0 | 2 | 18 | |
| TCGA | ANO8 | 57719 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of ANO8:
Generating mutation plots.
Highly correlated genes for ANO8:
Showing top 20/677 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO8 | PLEKHG6 | 0.786873 | 4 | 0 | 4 |
| ANO8 | RNLS | 0.772232 | 3 | 0 | 3 |
| ANO8 | AHCYL2 | 0.767097 | 3 | 0 | 3 |
| ANO8 | KCNK17 | 0.758983 | 3 | 0 | 3 |
| ANO8 | DHX32 | 0.756254 | 4 | 0 | 4 |
| ANO8 | ZNF717 | 0.752407 | 3 | 0 | 3 |
| ANO8 | MXI1 | 0.740904 | 3 | 0 | 3 |
| ANO8 | SLC12A6 | 0.740731 | 4 | 0 | 4 |
| ANO8 | WASF2 | 0.740201 | 3 | 0 | 3 |
| ANO8 | APEH | 0.737632 | 3 | 0 | 3 |
| ANO8 | MOCS2 | 0.737206 | 3 | 0 | 3 |
| ANO8 | NCOA1 | 0.734715 | 4 | 0 | 4 |
| ANO8 | ZNF681 | 0.733418 | 3 | 0 | 3 |
| ANO8 | CAPN7 | 0.72859 | 3 | 0 | 3 |
| ANO8 | ZFYVE1 | 0.726373 | 3 | 0 | 3 |
| ANO8 | ANKRD37 | 0.724972 | 3 | 0 | 3 |
| ANO8 | CCDC120 | 0.724759 | 4 | 0 | 4 |
| ANO8 | ENOSF1 | 0.723871 | 3 | 0 | 3 |
| ANO8 | ESR2 | 0.723315 | 3 | 0 | 3 |
| ANO8 | ZNF662 | 0.72024 | 4 | 0 | 4 |
For details and further investigation, click here
