| Full name: sperm acrosome associated 4 | Alias Symbol: SAMP14 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 171169 | HGNC ID: HGNC:16441 | Ensembl Gene: ENSG00000177202 | OMIM ID: 609932 |
| Drug and gene relationship at DGIdb | |||
Expression of SPACA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPACA4 | 171169 | 231054_at | -0.1105 | 0.6135 | |
| GSE26886 | SPACA4 | 171169 | 231054_at | -0.0961 | 0.5110 | |
| GSE45670 | SPACA4 | 171169 | 231054_at | 0.0009 | 0.9948 | |
| GSE53622 | SPACA4 | 171169 | 89913 | -1.7967 | 0.0000 | |
| GSE53624 | SPACA4 | 171169 | 89913 | -2.3212 | 0.0000 | |
| GSE63941 | SPACA4 | 171169 | 231054_at | 0.1194 | 0.4234 | |
| GSE77861 | SPACA4 | 171169 | 231054_at | -0.1186 | 0.4726 | |
| TCGA | SPACA4 | 171169 | RNAseq | -1.2094 | 0.0029 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SPACA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPACA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPACA4 | 171169 | 4 | 4 | 22 | |
| GSE20123 | SPACA4 | 171169 | 4 | 3 | 23 | |
| GSE43470 | SPACA4 | 171169 | 4 | 10 | 29 | |
| GSE46452 | SPACA4 | 171169 | 45 | 1 | 13 | |
| GSE47630 | SPACA4 | 171169 | 8 | 7 | 25 | |
| GSE54993 | SPACA4 | 171169 | 17 | 4 | 49 | |
| GSE54994 | SPACA4 | 171169 | 4 | 14 | 35 | |
| GSE60625 | SPACA4 | 171169 | 9 | 0 | 2 | |
| GSE74703 | SPACA4 | 171169 | 4 | 7 | 25 | |
| GSE74704 | SPACA4 | 171169 | 4 | 1 | 15 | |
| TCGA | SPACA4 | 171169 | 14 | 18 | 64 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of SPACA4:
Generating mutation plots.
Highly correlated genes for SPACA4:
Showing top 20/669 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPACA4 | PRSS27 | 0.731724 | 3 | 0 | 3 |
| SPACA4 | TMEM40 | 0.72863 | 3 | 0 | 3 |
| SPACA4 | SCEL | 0.725947 | 3 | 0 | 3 |
| SPACA4 | A2ML1 | 0.723347 | 3 | 0 | 3 |
| SPACA4 | PPL | 0.719587 | 3 | 0 | 3 |
| SPACA4 | CYP2C9 | 0.71328 | 3 | 0 | 3 |
| SPACA4 | RAPGEFL1 | 0.713179 | 3 | 0 | 3 |
| SPACA4 | ATP13A4 | 0.71216 | 3 | 0 | 3 |
| SPACA4 | ZG16 | 0.711916 | 3 | 0 | 3 |
| SPACA4 | RNF208 | 0.705217 | 4 | 0 | 4 |
| SPACA4 | SPINK7 | 0.701006 | 3 | 0 | 3 |
| SPACA4 | TWF1 | 0.699719 | 3 | 0 | 3 |
| SPACA4 | OTOF | 0.697122 | 3 | 0 | 3 |
| SPACA4 | MPZL3 | 0.693781 | 4 | 0 | 4 |
| SPACA4 | CYP2C18 | 0.692448 | 3 | 0 | 3 |
| SPACA4 | ABHD5 | 0.688465 | 3 | 0 | 3 |
| SPACA4 | NANOS2 | 0.687573 | 5 | 0 | 5 |
| SPACA4 | IL18 | 0.686731 | 3 | 0 | 3 |
| SPACA4 | YOD1 | 0.68369 | 4 | 0 | 3 |
| SPACA4 | RXFP3 | 0.682836 | 3 | 0 | 3 |
For details and further investigation, click here
