| Full name: kinesin family member 25 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 3834 | HGNC ID: HGNC:6390 | Ensembl Gene: ENSG00000125337 | OMIM ID: 603815 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF25 | 3834 | 208128_x_at | -0.0942 | 0.5887 | |
| GSE20347 | KIF25 | 3834 | 208128_x_at | -0.0647 | 0.4963 | |
| GSE23400 | KIF25 | 3834 | 208128_x_at | -0.1392 | 0.0017 | |
| GSE26886 | KIF25 | 3834 | 208128_x_at | -0.3092 | 0.0903 | |
| GSE29001 | KIF25 | 3834 | 208128_x_at | -0.1608 | 0.3088 | |
| GSE38129 | KIF25 | 3834 | 208128_x_at | -0.0662 | 0.5101 | |
| GSE45670 | KIF25 | 3834 | 208128_x_at | 0.0660 | 0.4520 | |
| GSE53622 | KIF25 | 3834 | 19932 | 0.4269 | 0.0027 | |
| GSE53624 | KIF25 | 3834 | 19932 | 0.1267 | 0.2197 | |
| GSE63941 | KIF25 | 3834 | 208128_x_at | -0.1302 | 0.3553 | |
| GSE77861 | KIF25 | 3834 | 208128_x_at | -0.1321 | 0.3004 | |
| TCGA | KIF25 | 3834 | RNAseq | 0.1599 | 0.8927 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIF25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF25 | 3834 | 3 | 6 | 21 | |
| GSE20123 | KIF25 | 3834 | 2 | 6 | 22 | |
| GSE43470 | KIF25 | 3834 | 3 | 0 | 40 | |
| GSE46452 | KIF25 | 3834 | 3 | 10 | 46 | |
| GSE47630 | KIF25 | 3834 | 7 | 7 | 26 | |
| GSE54993 | KIF25 | 3834 | 4 | 3 | 63 | |
| GSE54994 | KIF25 | 3834 | 10 | 8 | 35 | |
| GSE60625 | KIF25 | 3834 | 1 | 1 | 9 | |
| GSE74703 | KIF25 | 3834 | 3 | 0 | 33 | |
| GSE74704 | KIF25 | 3834 | 1 | 3 | 16 | |
| TCGA | KIF25 | 3834 | 14 | 20 | 62 |
Total number of gains: 51; Total number of losses: 64; Total Number of normals: 373.
Somatic mutations of KIF25:
Generating mutation plots.
Highly correlated genes for KIF25:
Showing top 20/647 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF25 | ZG16 | 0.719784 | 3 | 0 | 3 |
| KIF25 | STH | 0.688074 | 3 | 0 | 3 |
| KIF25 | SLC12A1 | 0.681815 | 3 | 0 | 3 |
| KIF25 | APOL5 | 0.665639 | 4 | 0 | 3 |
| KIF25 | MUSK | 0.665383 | 3 | 0 | 3 |
| KIF25 | HBQ1 | 0.6581 | 5 | 0 | 5 |
| KIF25 | CD4 | 0.656451 | 3 | 0 | 3 |
| KIF25 | MCHR2 | 0.655912 | 3 | 0 | 3 |
| KIF25 | ZNF135 | 0.655811 | 3 | 0 | 3 |
| KIF25 | KRTAP5-8 | 0.654877 | 7 | 0 | 7 |
| KIF25 | CAMK2B | 0.652906 | 7 | 0 | 6 |
| KIF25 | C1orf167 | 0.645531 | 4 | 0 | 3 |
| KIF25 | MYH8 | 0.643009 | 3 | 0 | 3 |
| KIF25 | OR1C1 | 0.639971 | 3 | 0 | 3 |
| KIF25 | PIK3R5 | 0.639763 | 5 | 0 | 5 |
| KIF25 | CLVS1 | 0.63868 | 4 | 0 | 3 |
| KIF25 | ACSBG1 | 0.63589 | 4 | 0 | 4 |
| KIF25 | SH2D1A | 0.635733 | 7 | 0 | 6 |
| KIF25 | LGR5 | 0.634681 | 4 | 0 | 4 |
| KIF25 | ABI3 | 0.633435 | 3 | 0 | 3 |
For details and further investigation, click here
