| Full name: G protein signaling modulator 3 | Alias Symbol: NG1|G18|G18.1a|G18.1b|G18.2|AGS4 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 63940 | HGNC ID: HGNC:13945 | Ensembl Gene: ENSG00000213654 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GPSM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPSM3 | 63940 | 204265_s_at | 0.3368 | 0.6172 | |
| GSE20347 | GPSM3 | 63940 | 204265_s_at | 0.0637 | 0.6243 | |
| GSE23400 | GPSM3 | 63940 | 204265_s_at | -0.0785 | 0.0981 | |
| GSE26886 | GPSM3 | 63940 | 204265_s_at | -0.1126 | 0.4629 | |
| GSE29001 | GPSM3 | 63940 | 214847_s_at | -0.1524 | 0.3904 | |
| GSE38129 | GPSM3 | 63940 | 204265_s_at | -0.0699 | 0.6646 | |
| GSE45670 | GPSM3 | 63940 | 204265_s_at | 0.0539 | 0.6890 | |
| GSE53622 | GPSM3 | 63940 | 8733 | -0.1413 | 0.1136 | |
| GSE53624 | GPSM3 | 63940 | 8733 | -0.3379 | 0.0000 | |
| GSE63941 | GPSM3 | 63940 | 204265_s_at | 0.4869 | 0.0799 | |
| GSE77861 | GPSM3 | 63940 | 204265_s_at | -0.1079 | 0.3592 | |
| GSE97050 | GPSM3 | 63940 | A_23_P219060 | 0.2616 | 0.2680 | |
| SRP007169 | GPSM3 | 63940 | RNAseq | 1.2683 | 0.0687 | |
| SRP008496 | GPSM3 | 63940 | RNAseq | 0.5130 | 0.2483 | |
| SRP064894 | GPSM3 | 63940 | RNAseq | 0.6492 | 0.0215 | |
| SRP133303 | GPSM3 | 63940 | RNAseq | -0.0468 | 0.8158 | |
| SRP159526 | GPSM3 | 63940 | RNAseq | -0.5805 | 0.3854 | |
| SRP193095 | GPSM3 | 63940 | RNAseq | 0.4320 | 0.0818 | |
| SRP219564 | GPSM3 | 63940 | RNAseq | 0.7558 | 0.0876 | |
| TCGA | GPSM3 | 63940 | RNAseq | 0.0978 | 0.4122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPSM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPSM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPSM3 | 63940 | 5 | 1 | 24 | |
| GSE20123 | GPSM3 | 63940 | 5 | 1 | 24 | |
| GSE43470 | GPSM3 | 63940 | 5 | 1 | 37 | |
| GSE46452 | GPSM3 | 63940 | 1 | 10 | 48 | |
| GSE47630 | GPSM3 | 63940 | 7 | 4 | 29 | |
| GSE54993 | GPSM3 | 63940 | 2 | 1 | 67 | |
| GSE54994 | GPSM3 | 63940 | 11 | 4 | 38 | |
| GSE60625 | GPSM3 | 63940 | 0 | 1 | 10 | |
| GSE74703 | GPSM3 | 63940 | 5 | 0 | 31 | |
| GSE74704 | GPSM3 | 63940 | 2 | 0 | 18 | |
| TCGA | GPSM3 | 63940 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of GPSM3:
Generating mutation plots.
Highly correlated genes for GPSM3:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPSM3 | LIMD1 | 0.823352 | 3 | 0 | 3 |
| GPSM3 | LYPLA2 | 0.775961 | 3 | 0 | 3 |
| GPSM3 | ABCA4 | 0.763394 | 5 | 0 | 5 |
| GPSM3 | ADAP1 | 0.75513 | 3 | 0 | 3 |
| GPSM3 | LRFN4 | 0.741454 | 3 | 0 | 3 |
| GPSM3 | CSN3 | 0.73391 | 3 | 0 | 3 |
| GPSM3 | ADAMTS13 | 0.733708 | 3 | 0 | 3 |
| GPSM3 | KLK2 | 0.732351 | 3 | 0 | 3 |
| GPSM3 | CD27 | 0.724204 | 8 | 0 | 7 |
| GPSM3 | PTPRCAP | 0.720908 | 9 | 0 | 7 |
| GPSM3 | AGRP | 0.715787 | 3 | 0 | 3 |
| GPSM3 | C6orf15 | 0.715627 | 3 | 0 | 3 |
| GPSM3 | NFIA-AS2 | 0.712033 | 3 | 0 | 3 |
| GPSM3 | FOXB1 | 0.711038 | 3 | 0 | 3 |
| GPSM3 | PRKAR1B | 0.710143 | 4 | 0 | 4 |
| GPSM3 | POM121L12 | 0.703654 | 4 | 0 | 4 |
| GPSM3 | RNF167 | 0.702868 | 4 | 0 | 4 |
| GPSM3 | ZG16 | 0.700184 | 3 | 0 | 3 |
| GPSM3 | RCOR2 | 0.698364 | 3 | 0 | 3 |
| GPSM3 | FNDC9 | 0.69782 | 3 | 0 | 3 |
For details and further investigation, click here
