| Full name: zinc finger protein 254 | Alias Symbol: HD-ZNF1|BMZF-5 | ||
| Type: protein-coding gene | Cytoband: 19p13 | ||
| Entrez ID: 9534 | HGNC ID: HGNC:13047 | Ensembl Gene: ENSG00000213096 | OMIM ID: 604768 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF254:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF254 | 9534 | 242602_x_at | -0.1646 | 0.6163 | |
| GSE20347 | ZNF254 | 9534 | 206862_at | -0.4432 | 0.0017 | |
| GSE23400 | ZNF254 | 9534 | 206862_at | -0.1079 | 0.0000 | |
| GSE26886 | ZNF254 | 9534 | 242602_x_at | -0.2553 | 0.0468 | |
| GSE29001 | ZNF254 | 9534 | 206862_at | -0.6528 | 0.0497 | |
| GSE38129 | ZNF254 | 9534 | 206862_at | -0.4354 | 0.0004 | |
| GSE45670 | ZNF254 | 9534 | 1559449_a_at | -0.1067 | 0.8250 | |
| GSE53622 | ZNF254 | 9534 | 103952 | -0.0721 | 0.4598 | |
| GSE53624 | ZNF254 | 9534 | 103952 | -0.1445 | 0.0535 | |
| GSE63941 | ZNF254 | 9534 | 242602_x_at | 0.0906 | 0.8446 | |
| GSE77861 | ZNF254 | 9534 | 242602_x_at | -0.1061 | 0.6254 | |
| GSE97050 | ZNF254 | 9534 | A_32_P144908 | -0.0349 | 0.9440 | |
| SRP007169 | ZNF254 | 9534 | RNAseq | -2.8286 | 0.0000 | |
| SRP008496 | ZNF254 | 9534 | RNAseq | -1.7243 | 0.0002 | |
| SRP064894 | ZNF254 | 9534 | RNAseq | -0.6099 | 0.0283 | |
| SRP133303 | ZNF254 | 9534 | RNAseq | -0.3191 | 0.2377 | |
| SRP159526 | ZNF254 | 9534 | RNAseq | -0.5091 | 0.0718 | |
| SRP193095 | ZNF254 | 9534 | RNAseq | -1.0737 | 0.0000 | |
| SRP219564 | ZNF254 | 9534 | RNAseq | -0.8973 | 0.1403 | |
| TCGA | ZNF254 | 9534 | RNAseq | -0.4553 | 0.0072 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ZNF254 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF254:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF254 | 9534 | 6 | 4 | 20 | |
| GSE20123 | ZNF254 | 9534 | 6 | 3 | 21 | |
| GSE43470 | ZNF254 | 9534 | 6 | 6 | 31 | |
| GSE46452 | ZNF254 | 9534 | 47 | 1 | 11 | |
| GSE47630 | ZNF254 | 9534 | 8 | 6 | 26 | |
| GSE54993 | ZNF254 | 9534 | 17 | 3 | 50 | |
| GSE54994 | ZNF254 | 9534 | 7 | 12 | 34 | |
| GSE60625 | ZNF254 | 9534 | 9 | 0 | 2 | |
| GSE74703 | ZNF254 | 9534 | 6 | 4 | 26 | |
| GSE74704 | ZNF254 | 9534 | 3 | 3 | 14 | |
| TCGA | ZNF254 | 9534 | 18 | 16 | 62 |
Total number of gains: 133; Total number of losses: 58; Total Number of normals: 297.
Somatic mutations of ZNF254:
Generating mutation plots.
Highly correlated genes for ZNF254:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF254 | ZNF727 | 0.76822 | 3 | 0 | 3 |
| ZNF254 | ZNF728 | 0.76017 | 3 | 0 | 3 |
| ZNF254 | ZNF729 | 0.712529 | 3 | 0 | 3 |
| ZNF254 | ZNF675 | 0.676972 | 10 | 0 | 9 |
| ZNF254 | PIK3C3 | 0.675067 | 3 | 0 | 3 |
| ZNF254 | SVIP | 0.667966 | 3 | 0 | 3 |
| ZNF254 | PLAA | 0.621214 | 6 | 0 | 5 |
| ZNF254 | FAM221A | 0.619776 | 4 | 0 | 3 |
| ZNF254 | ZNF43 | 0.61831 | 9 | 0 | 8 |
| ZNF254 | ZNF253 | 0.617916 | 10 | 0 | 8 |
| ZNF254 | BBIP1 | 0.613651 | 4 | 0 | 4 |
| ZNF254 | YAP1 | 0.609919 | 3 | 0 | 3 |
| ZNF254 | ZNF93 | 0.609841 | 10 | 0 | 8 |
| ZNF254 | ZNF430 | 0.609547 | 11 | 0 | 8 |
| ZNF254 | ZNF273 | 0.60927 | 11 | 0 | 10 |
| ZNF254 | SDHD | 0.608927 | 5 | 0 | 4 |
| ZNF254 | ZNF85 | 0.608811 | 13 | 0 | 9 |
| ZNF254 | SYNPO2L | 0.607951 | 4 | 0 | 4 |
| ZNF254 | ZNF91 | 0.601544 | 12 | 0 | 8 |
| ZNF254 | MYB | 0.598673 | 4 | 0 | 3 |
For details and further investigation, click here
